Abstract
Collagenous colitis (CC) is a variant of microscopic colitis that causes chronic, non-bloody, and watery diarrhea. The natural history of CC is generally benign and serious complications are rare. Perforation, especially spontaneous perforation, is a particularly rare complication. A 90-year-old woman presented with acute abdominal pain. She was diagnosed with peritonitis due to colonic perforation, and partial colectomy was performed. Macroscopic findings showed well-circumscribed longitudinal ulcer, and a pathological examination revealed descending colon perforation with CC. She had no history of examination and the case was considered to be spontaneous. The postoperative course was uneventful and she had no recurrence of CC after changing from the suspected drug (lansoprazole) to an H2-blocker. The characteristics of perforation by CC are characteristic longitudinal ulcer and micro-perforation. If it can be diagnosed accurately, conservative treatment may be an option. In spontaneous cases, the history of medication and the site of perforation may assist in this decision.
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Abbreviations
- CC:
-
Collagenous colitis
- LPZ:
-
Lansoprazole
- CS:
-
Colonoscopy
- PPIs:
-
Proton pump inhibitors
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TS and TU contributed to the study conception and design, data collection, and analysis and interpretation of data. EB contributed to the data collection and interpretation of data. TT and TY were involved in the decision to publish or the preparation of the manuscript. AY contributed to the study supervision. All authors read and approved the final manuscript.
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Sadamitsu, T., Ueda, T., Boku, E. et al. Spontaneous colonic perforation with collagenous colitis in an elderly patient. Clin J Gastroenterol 15, 1083–1087 (2022). https://doi.org/10.1007/s12328-022-01707-4
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DOI: https://doi.org/10.1007/s12328-022-01707-4