Abstract
Gastrointestinal tuberculosis manifesting as isolated duodenal involvement is uncommon. We present a case of 52 years old man with post-prandial abdominal pain, early satiety and weight loss. Upper endoscopy showed circumferential duodenal stricture adjacent to the ampulla with nodularity, erythema, and ulcerations of the overlying mucosa causing gastric outlet obstruction. Biopsy of duodenal stricture revealed chronic duodenitis and the patient was treated with acid suppression therapy. Endoscopic balloon dilation was also performed with no response. Abdominal computer tomography scan showed multiple enlarged abdominal lymph nodes and subsequent duodenal tissue culture was positive for Mycobacterium tuberculosis. His symptoms and duodenal stricture resolved completely after treatment with anti-tuberculous regimen.
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References
Marshall JB. Tuberculosis of the gastrointestinal tract and peritoneum. Am J Gastroenterol. 1993;88:989–99.
Debi U, Ravisankar V, Prasad KK, et al. Abdominal tuberculosis of the gastrointestinal tract: revisited. World J Gastroenterol. 2014;20:14831–40.
Kochhar R, Kochhar S. Endoscopic balloon dilation for benign gastric outlet obstruction in adults. World J Gastrointest Endosc. 2010;2:29–35.
Balikian JP, Yenikomshian SM, Jidejian YD. Tuberculosis of the pyloro-duodenal area: report of four cases. Am J Roentgenol Radium Ther Nucl Med. 1967;101:414–20.
Sharma BC, Prasad H, Bhasin DK, et al. Gastroduodenal tuberculosis presenting with massive hematemesis in a pregnant woman. J Clin Gastroenterol. 2000;30:336.
Rao YG, Pande GK, Sahni P, et al. Gastroduodenal tuberculosis management guidelines, based on a large experience and a review of the literature. Can J Surg. 2004;47:364–8.
Gupta SK, Jain AK, Gupta JP, et al. Duodenal tuberculosis. Clin Radiol. 1988;39:159–61.
Fernandez OU, Canizares LL. Tuberculous mesenteric lymphadenitis presenting as pyloric stenosis. Dig Dis Sci. 1995;40:1909–12.
Berney T, Badaoui E, Totsch M, et al. Duodenal tuberculosis presenting as acute ulcer perforation. Am J Gastroenterol. 1998;93:1989–91.
Miyamoto S, Furuse J, Maru Y, et al. Duodenal tuberculosis with a choledocho-duodenal fistula. J Gastroenterol Hepatol. 2001;16:235–8.
Stanley JH, Yantis PL, Marsh WH. Periportal tuberculous adenitis: a rare cause of obstructive jaundice. Gastrointest Radiol. 1984;9:227–9.
Shah P, Ramakantan R, Deshmukh H. Obstructive jaundice–an unusual complication of duodenal tuberculosis: treatment with transhepatic balloon dilatation. Indian J Gastroenterol. 1991;10:62–3.
Eadie DG, Pollock DJ. A complicated aortoduodenal fistula: a case report. Br J Surg. 1968;55:314–7.
Schwartz DT, Garnes HA, Lattimer JK, et al. Pyeloduodenal fistula due to tuberculosis. J Urol. 1970;104:373–5.
Udgirkar S, Surude R, Zanwar V, et al. Gastroduodenal tuberculosis: a case series and review of literature. Clin Med Insights Gastroenterol. 2018;11:1179552218790566.
Rohwedder JJ. Abdominal tuberculosis: a disease poised for reappearance. N Y State J Med. 1989;89:252–4.
Tandon RK, Pastakia B. Duodenal tuberculosis as seen by duodenoscopy. Am J Gastroenterol. 1976;66:483–6.
Misra D, Rai RR, Nundy S, et al. Duodenal tuberculosis presenting as bleeding peptic ulcer. Am J Gastroenterol. 1988;83:203–4.
Brisson-Noel A, Aznar C, Chureau C, et al. Diagnosis of tuberculosis by DNA amplification in clinical practice evaluation. Lancet. 1991;338:364–6.
Uzunkoy A, Harma M, Harma M. Diagnosis of abdominal tuberculosis: experience from 11 cases and review of the literature. World J Gastroenterol. 2004;10:3647–9.
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Arunchai Chang, Tanyaporn Chantarojanasiri and Nonthalee Pausawasdi declare that they have no conflict of interest.
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Chang, A., Chantarojanasiri, T. & Pausawasdi, N. Duodenal tuberculosis; uncommon cause of gastric outlet obstruction. Clin J Gastroenterol 13, 198–202 (2020). https://doi.org/10.1007/s12328-019-01007-4
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DOI: https://doi.org/10.1007/s12328-019-01007-4