Abstract
Squamous odontogenic tumor (SOT) is a rare benign but locally infiltrative tumor often misdiagnosed as other entities, such as ameloblastoma and squamous cell carcinoma, due to overlap** morphological findings. We document here the clinicopathological and imaging findings of an aggressive intraosseous SOT in the posterior left region of the maxilla in a 25-year-old male patient. On intraoral examination, the tumor extended from the region of the left lateral incisor to the upper left premolar and was covered by reddish mucosa, with discrete areas of ulceration. Imaging exams revealed an osteolytic lesion causing thinning, erosion, and buccal and lingual cortical plate perforation associated with an impacted canine. Microscopically, the tumor showed a proliferation of islands of well-differentiated squamous epithelium in a variably collagenized background. The peripheral cells of the islands were flat or slightly cuboidal and did not exhibit nuclei with peripheral palisade and reverse polarization. The diagnosis of SOT was rendered. The patient underwent surgical resection and has been under clinical follow-up for approximately 12 months with no signs of recurrence. A careful morphological evaluation is essential to avoid misdiagnosis and ensure a satisfactory treatment approach.
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References
Soluk-Tekkesin M, Wright JM (2022) The World Health Organization classification of odontogenic lesions: a summary of the changes of the 2022 (5th) edition. Turk Patoloji Derg 38(2):168–184. https://doi.org/10.5146/tjpath.2022.01573
Upadhyaya JD, Banasser A, Cohen DM, Kashtwari D, Bhattacharyya I, Islam MN (2021) Squamous odontogenic tumor: review of the literature and report of a new case. J Oral Maxillofac Surg 79(1):164–176. https://doi.org/10.1016/j.joms.2020.06.031
Chrcanovic BR, Gomez RS (2018) Squamous odontogenic tumor and squamous odontogenic tumor-like proliferations in odontogenic cysts: an updated analysis of 170 cases reported in the literature. J CranioMaxillofac Surg 46(3):504–510. https://doi.org/10.1016/j.jcms.2017.12.023
Funding
Bruno Augusto Benevenuto de Andrade is a research fellow of Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) E-26/201.289/2022. Bruno Augusto Benevenuto de Andrade and Fabio Ramôa Pires are research fellows of Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq).
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Conceptualization, MSI, BABA and FRP.; methodology, JLSC; formal analysis, MSI and BABA; investigation, JLSC; resources, MSI, BABA. and FRP; data curation, NAF; writing—original draft preparation, JLSC.; writing—review and editing, BABA, ILC, CHF, NAF and SAFA; visualization, MSI, BABA and FRP; supervision, MSI and BABA; project administration, MSI and BABA.; funding acquisition, BABA. All authors have read and agreed to the published version of the manuscript.
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Cunha, J.L.S., de Andrade, B.A.B., Cavalcante, I.L. et al. Squamous Odontogenic Tumor in the Posterior Region of Maxilla. Head and Neck Pathol 17, 1067–1070 (2023). https://doi.org/10.1007/s12105-023-01585-3
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DOI: https://doi.org/10.1007/s12105-023-01585-3