SpringerLink
Log in

What Is the Non-calcifying Langerhans Cell-Rich Variant of Calcifying Epithelial Odontogenic Tumor?

  • Letter to the Editor
  • Published:
Head and Neck Pathology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Santosh N, McNamara KK, Kalmar JR, Iwenofu OH. Non-calcifying Langerhans cell-rich variant of calcifying epithelial odontogenic tumor: a distinct entity with predilection for anterior maxilla. Head Neck Pathol. https://doi.org/10.1007/s12105-018-0958-7.

  2. Chrcanovic BR, Gomez RS. Calcifying epithelial odontogenic tumor: an updated analysis of 339 cases reported in the literature. J Craniomaxillofac Surg. 2017;45:1117–23.

    Article  PubMed  Google Scholar 

  3. Chi AC, Neville BW. Odontogenic cysts and tumors. Surg Pathol. 2011;4:1027–91.

    Article  Google Scholar 

  4. Zhou CX, Li TJ. A clinicopathologic study on central odontogenic fibroma: with special reference to amyloid variant. Oral Surg Oral Med Oral Pathol Oral Radiol. https://doi.org/10.1016/j.oooo.2018.08.019.

  5. Ganatra S, Castro H, Toporowski B, Hohn F, Peters E. Non-calcifying Langerhans cell-associated epithelial odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;116:e506–7.

    Article  Google Scholar 

  6. Lee W, Myung NH, Kim CH. Calcifying epithelial odontogenic tumor: report of three cases with immunohistochemical study. Int J Clin Exp Pathol. 2016;9:5733–9.

    CAS  Google Scholar 

  7. Smith RA, Roman RS, Hansen LS, Lundell WJ, Riley RW. The calcifying epithelial odontogenic tumor. J Oral Surg. 1977;35:160–6.

    CAS  PubMed  Google Scholar 

  8. Hafian H, Mauprivez C, Furon V, Pluot M, Lefevre B. Tumeur de Pindborg: à propos d’une forme peu différenciée et sans calcification. Rev Stomatol Chir Maxillofac. 2004;105:227–30.

    Article  CAS  PubMed  Google Scholar 

  9. Regezi JA, Kerr DA, Courtney RM. Odontogenic tumors: analysis of 706 cases. J Oral Surg. 1978;36:771–8.

    CAS  PubMed  Google Scholar 

  10. Smith RA, Hansen LS, DeDecker D. Atypical calcifying epithelial odontogenic tumor of the maxilla. J Am Dent Assoc. 1980;100:706–9.

    Article  CAS  PubMed  Google Scholar 

  11. Gardner DG. The central odontogenic fibroma: an attempt at clarification. Oral Surg Oral Med Oral Pathol. 1980;50:425–32.

    Article  CAS  PubMed  Google Scholar 

  12. Papageorge MB, Giunta J, Nersasian RR. A case of a central odontogenic fibroma presenting a differential diagnostic problem. J Mass Dent Soc. 1993;42:97–9.

    CAS  PubMed  Google Scholar 

  13. Dunlap CL. Odontogenic fibroma. Semin Diagn Pathol. 1999;16:293–6.

    CAS  PubMed  Google Scholar 

  14. Whitt JC, Barker BF, Dunlap CL. Central odontogenic fibroma, WHO type: report of a series of nine cases. 2009 annual meeting of the American Academy of Oral & Maxillofacial Pathology. Poster program 10. Canada: May 19 2009.

  15. Eversole LR. Odontogenic fibroma, including amyloid and ossifying variants. Head Neck Pathol. 2011;5:335–43.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Mittal N, Hyam D, Jain S, Lui M, Dahlstrom JE. Central odontogenic fibroma of maxilla: significance of coexisting Langerhans cells. Pathology 2014;46:9–10.

    Article  Google Scholar 

  17. Carolina A, Motta F, Filippin MS, et al. Amyloid/dendritic cell associated central odontogenic fibroma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;120:e77.

    Google Scholar 

  18. Dunphy L, Shah S, Halsnad M, Amel-Kashipaz R, Praveen P. Odontogenic myxoma presenting as a spontaneous oro-nasal fistula: a case report. Oral Surg. 2013;6:77–9.

    Article  Google Scholar 

  19. Prætorius F. Odontogenic tumors. In: Barnes L, editor. Surgical pathology of the head and neck. 3rd ed. Vol. 3. New York: Informa Healthcare; 2009. pp. 1230–5, 1276–80.

    Google Scholar 

  20. Philipsen HP, Reichart PA. Calcifying epithelial odontogenic tumour: biological profile based on 181 cases from the literature. Oral Oncol. 2000;36:17–26.

    Article  CAS  PubMed  Google Scholar 

  21. Morgan PR. Odontogenic tumors: a review. Periodontol 2000. 2011;57:160–76.

    Article  PubMed  Google Scholar 

  22. Brannon RB. Central odontogenic fibroma, myxoma (odontogenic myxoma, fibromyxoma), and central odontogenic granular cell tumor. Oral Maxillofac Surg Clin N Am. 2004;16:359–74.

    Article  Google Scholar 

  23. Ide F, Shimoyama T, Horie N. Critique of “odontogenic myxoma presenting as a spontaneous oro-nasal fistula. Oral Surg. 2016;9:142–3.

    Article  Google Scholar 

  24. Handlers JP, Abrams AM, Melrose RJ, Danforth R. Central odontogenic fibroma: clinicopathologic features of 19 cases and review of the literature. J Oral Maxillofac Surg. 1991;49:46–54.

    Article  CAS  PubMed  Google Scholar 

  25. Kaffe I, Buchner A. Radiologic features of central odontogenic fibroma. Oral Surg Oral Med Oral Pathol. 1994;78:811–8.

    Article  CAS  PubMed  Google Scholar 

  26. Neville BW, Damm DD, Allen CM, Chi AC. Oral and maxillofacial pathology. 4th ed. Philadelphia: Saunders; 2016. pp. 666–8, 676–8.

    Google Scholar 

  27. Kaplan I, Buchner A, Calderon S, Kaffe I. Radiological and clinical features of calcifying epithelial odontogenic tumour. Dentomaxillofac Radiol. 2001;30:22–8.

    Article  CAS  PubMed  Google Scholar 

  28. Fowler C, Tomich C, Brannon R, Houston G. Central odontogenic fibroma: clinicopathologic features of 24 cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1993;76:587.

    Article  Google Scholar 

  29. Bilodeau EA, Collins BM. Odontogenic cysts and neoplasms. Surg Pathol. 2017;10:177–222.

    Article  Google Scholar 

  30. Odell EW, Morgan PR. Biopsy pathology of the oral tissues. London: Chapman & Hall; 1998. pp. 388–94.

    Google Scholar 

  31. Aufdermaur M. Pindborg tumor. J Cancer Res Clin Oncol. 1981;101:227–30.

    Article  CAS  PubMed  Google Scholar 

  32. Hotta F, Mizohata M, Takehara S, Kameyama Y. A case of atypical calcifying epithelial odontogenic tumor in the left maxilla. Jpn J Oral Maxillofac Surg. 1984;30:2051.

    Google Scholar 

  33. Kaushal S, Mathur SR, Vilay M, Rustagi A. Calcifying epithelial odontogenic tumor (Pindborg tumor) without calcification: a rare entity. J Oral Maxillofac Pathol. 2012;16:110–2.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Mutalik VS, Nichat P, Carnelio S, Solomon M, Radhakrishnan R. Clear cell variant of calcifying epithelial odontogenic tumor without calcification. J Contemp Dent Pract. 2014;15:119–204.

    Article  PubMed  Google Scholar 

  35. Taneeru S, Guttikonda VR, Korlepara R, Gaddipati R, Kundoor VK. Non caclcifying type of calcifying epithelial odontogenic tumor: an unusual case report with special emphasis on histogenesis of calcifications. J Maxillofac Oral Surg. 2017;16:253–7.

    Article  PubMed  Google Scholar 

  36. Brito CM, Silva LP, Neves RA, Castro LA, Vênico EF. Central non-calcifying odontogenic tumor: a rare case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017;124:e95.

    Article  Google Scholar 

  37. Kramer IRH, Pindborg JJ, Shear M. Histological ty** of odontogenic tumours. 2nd ed. Berlin: Springer; 1992. pp. 15–6.

    Book  Google Scholar 

  38. Poomsawat S, Punyasingh J. Calcifying epithelial odontogenic tumor: an immunohistochemical case study. J Mol Hist. 2007;38:103–9.

    Article  Google Scholar 

  39. Afrogheh A, Schneider J, Mohamed N, Hille J. Calcifying epithelial odontogenic tumor with clear Langerhans cells: a novel variant, report of a case and review of the literature. Head Neck Pathol. 2014;8:214–9.

    Article  PubMed  Google Scholar 

  40. Munteanu C, Pirici D, Stepan AE, Camen A, Margaritescu C. Maxillary calcifying epithelial odontogenic tumor with sinus and buccal vestibule extension: a case report and immunohistochemical study. Diagn Pathol. 2016;11:134.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Wu YC, Wang YP, Chang JYF, Chen HM, Sun A, Chiang CP. Langerhans cells in odontogenic epithelia of odontogenic fibromas. J Formos Med Assoc. 2013;112:756–60.

    Article  CAS  PubMed  Google Scholar 

  42. Mosqueda-Taylor A, Martínez-Meta G, Carlos-Bregni R, et al. Central odontogenic fibroma: new findings and report of a multicentric collaborative study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112:349–58.

    Article  PubMed  Google Scholar 

  43. Kabasawa Y, Nagumo K, Takeda Y, et al. Amelogenin positive cells scattered in the interstitial component of odontogenic fibromas. J Clin Pathol. 2008;61:851–5.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, 1-1 Keyakidai, Sakado, Saitama, 350-0283, Japan

    Fumio Ide, Yuji Miyazaki, Kentaro Kikuchi & Kaoru Kusama

  2. Department of Diagnostic Pathology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan

    Fumio Ide & Naoyuki Matsumoto

Authors
  1. Fumio Ide
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Naoyuki Matsumoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yuji Miyazaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kentaro Kikuchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Kaoru Kusama
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Fumio Ide.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ide, F., Matsumoto, N., Miyazaki, Y. et al. What Is the Non-calcifying Langerhans Cell-Rich Variant of Calcifying Epithelial Odontogenic Tumor?. Head and Neck Pathol 13, 489–491 (2019). https://doi.org/10.1007/s12105-018-0968-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12105-018-0968-5

Search

Navigation