Abstract
Objective
To compare the acquisition time, diagnostic efficacy, and image quality of the newer compressed SENSE 3D MRCP (CS-3D MRCP) with conventional 3D MRCP (C-3D MRCP) in children with pancreatitis.
Methods
A total of 24 children (2–17 y) diagnosed with pancreatitis were included in this study. The children underwent CS-3D MRCP and C-3D MRCP sequences. C-3D MRCP and CS-3D MRCP images were evaluated for the acquisition time duration, visualization of the pancreaticobiliary ducts, background suppression, image quality degradation by artifacts, and overall image quality by the two radiologists independently. Paired sample t-test was used to compare the acquisition time, the McNemar test for the image quality features, and the kappa coefficient was used for interobserver agreement.
Results
A two-fold decrease in the acquisition time of CS-3D MRCP (~148 ± 61 s) was seen, compared to C-3D MRCP (~310 ± 98 s), p < 0.001. The median scores for overall image quality on CS-3D MRCP and C-3D MRCP, respectively, were 2.05 ± 0.52 and 2.21 ± 0.53 (p = 0.18) for both radiologists. No significant difference was seen for the visibility of ducts, background suppression, and artifacts between the two radiologists, with substantial to almost perfect agreement seen for the different findings.
Conclusion
The application of compressed SENSE 3D MRCP in children with pancreatitis results in a two-fold reduction in acquisition time with acceptable image quality. This may help in reducing the need for long sedation in children requiring anesthesia support for the MRCP and potentially help in reducing motion artifacts.
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Acknowledgements
The authors thank Dr Indrajit Saha and Mr. Rohit Mishra, Philips India Ltd. for hel** in optimizing the compressed SENSE sequence for MRCP. The authors also thank Mr. Kamaljeet and Ms. Kiran Gargya, Department of Radiodiagnosis and Imaging, PGIMER, Chandigarh, India for hel** in the acquisition of the cases.
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KSS made substantial contributions to the conception or design of the work; acquisition, analysis, and interpretation of data; drafted the work and revised it critically for important intellectual content; approved the version to be published; agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. MM made substantial contributions to the conception or design of the work; acquisition, analysis, and interpretation of data; drafted the work and revised it critically for important intellectual content; approved the version to be published. AB, SBL and AKS made substantial contributions to the analysis, and interpretation of data; revised the work critically for important intellectual content; approved the version to be published. KSS will act as the guarantor for this paper.
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Informed written consent was obtained from the parents or guardians of all children included in the present study. Assent was also obtained from children aged 7 y and above.
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Kushaljit Singh Sodhi and Muniraju Maralakunte are joint first authors
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Sodhi, K.S., Maralakunte, M., Bhatia, A. et al. Utility of the New Faster Compressed SENSE MRCP at 3 Tesla MRI in Children with Pancreatitis. Indian J Pediatr 90, 1210–1215 (2023). https://doi.org/10.1007/s12098-022-04403-w
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DOI: https://doi.org/10.1007/s12098-022-04403-w