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Pure Tone Audiometry in Anemia Patients

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Aim

Anaemia is a prevalent medical condition that impacts a significant proportion of the worldwide populace. While the cardiovascular and respiratory systems’ influence on anaemia has been extensively researched, its effect on the auditory system remains unclear. The objective of this investigation was to assess the pure tone audiometry of individuals with anaemia and establish a connection between the type of hearing impairment and the level of anaemia, if any.

Materials and Methods

This cross-sectional study comprised 100 patients who were diagnosed with anaemia. All study participants underwent a thorough general examination and hearing assessment, which encompassed tuning fork tests, and pure-tone audiometry. Statistical analysis was utilized to determine the type and severity of hearing loss and its correlation with the degree of anaemia.

Results

Our research findings indicate that 46.8% of moderately anaemic patients and 62.9% of patients with severe anaemia exhibited sensorineural hearing loss. A significant correlation was observed between the degree of anaemia (p < 0.05) and hearing loss. Our research findings indicate that individuals with moderate and severe anaemia exhibit a notably greater incidence of hearing impairment in comparison to those with mild anaemia.

Conclusion

The research findings thus suggest a potential correlation between anaemia and auditory impairment. The timely identification and management of anaemia could potentially play a crucial role in preventing or reducing hearing impairment among individuals with anaemia. Additional research is required to clarify the mechanisms that underlie this association and to investigate possible interventions for mitigating the risk of hearing impairment in individuals with anaemia.

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References

  1. Bagai A, Thavendiranathan P, Detsky AS (2006) Does this patient have hearing impairment? JAMA 295(4):416–428

    Article  CAS  PubMed  Google Scholar 

  2. Lin FR, Niparko JK, Ferrucci L (2011) Hearing loss prevalence in the United States. Arch Intern Med 171(20):1851–1852

    Article  PubMed  PubMed Central  Google Scholar 

  3. Lin BM, Curhan SG, Wang M, Eavey R, Stankovic KM, Curhan GC (2016) Hypertension, diuretic use, and risk of hearing loss. Am J Med 129(4):416–422

    Article  CAS  PubMed  Google Scholar 

  4. Johnson-Wimbley TD, Graham DY (2011) Diagnosis and management of iron Deficiency anaemia in the 21st century. TherapAdvGastroenterol 4(3):177–184

    Google Scholar 

  5. Sun AH, **ao SZ, Li BS, Li ZJ, Wang TY, Zhang YS (1987) Iron Deficiency and hearing loss: experimental study in growing rats. ORL J OtorhinolaryngolRelat Spec 49(3):118–122

    Article  CAS  Google Scholar 

  6. Sun A-H, Wang Z-M, **ao S-Z, Li Z-J, Zheng Z, Li J-Y (1992) Sudden sensorineural hearing loss induced by experimental iron Deficiency in rats. ORL J OtorhinolaryngolRelat Spec 54(5):246–250

    Article  CAS  Google Scholar 

  7. Cappellini MD, Motta I (2015) Anaemia in clinical practice-definition and classification: does Hemoglobin Change with Aging? Semin Hematol 52(4):261–269

    Article  PubMed  Google Scholar 

  8. Sharif N, Das B, Alam A (2023) Prevalence of anaemia among reproductive women in different social group in India: cross-sectional study using nationally representative data. PLoS ONE, 18(2), e0281015

  9. Nakashima T, Naganawa S, Sone M et al (2003) Disorders of cochlear blood flow. Brain Res Brain Res Rev 43(1):17–28

    Article  PubMed  Google Scholar 

  10. Chang Y-L, Hung S-H, Ling W, Lin H-C, Li H-C, Chung S-D (2013) Association between ischemic Stroke and iron-Deficiency anaemia: a population-based study. PLoS ONE 8(12):e82952

    Article  PubMed  PubMed Central  Google Scholar 

  11. Dubyk MD, Card RT, Whiting SJ, Boyle CAJ, Zlotkin SH, Paterson PG (2012) Iron Deficiency anaemia prevalence at first Stroke or transient ischemic Attack. Can J Neurol Sci 39(2):189–195

    Article  PubMed  Google Scholar 

  12. Chung S-D, Chen P-Y, Lin H-C, Hung S-H (2014) Sudden sensorineural hearing loss associated with iron-Deficiency anaemia: a population-based study. JAMA Otolaryngol Head Neck Surg 140(5):417–422

    Article  PubMed  Google Scholar 

  13. Kuku I, Kaya E, Yologlu S, Gokdeniz R, Baydin A (2009) Platelet counts in adults with iron Deficiency anaemia. Platelets 20(6):401–405

    Article  CAS  PubMed  Google Scholar 

  14. Franchini M, Targher G, Montagnana M, Lippi G (2008) Iron and Thrombosis. Ann Hematol 87(3):167–173

    Article  CAS  PubMed  Google Scholar 

  15. Karpatkin S, Garg SK, Freedman ML (1974) Role of iron as a regulator of thrombopoiesis. Am J Med 57(4):521–525

    Article  CAS  PubMed  Google Scholar 

  16. Beguin Y (1999) Erythropoietin and platelet production. Haematologica 84(6):541–547

    CAS  PubMed  Google Scholar 

  17. Todorich B, Pasquini JM, Garcia CI, Paez PM, Connor JR (2009) Oligodendrocytes and myelination: the role of iron. Glia 57(5):467–478

    Article  PubMed  Google Scholar 

  18. Tagoe T, Barker M, Jones A, Allcock N, Hamann M (2014) Auditory nerve perinodal dysmyelination in noise-induced hearing loss. J Neurosci 34(7):2684–2688

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Brown AM, Hamann M (2014) Computational modeling of the effects of auditory nerve dysmyelination. Front Neuroanat 8:73

    Article  PubMed  PubMed Central  Google Scholar 

  20. Vos T, Allen C, Arora M, Barber RM, Brown A, Carter A, Casey DC, Charlson FJ, Chen AZ, Coggeshall M et al (2016) Global, regional, and national incidence, prevalence, and years lived with disability for 310 Diseases and injuries, 1990–2015: a systematic analysis for the global burden of Disease Study 2015. Lancet 388(10053):1545–1602

    Article  Google Scholar 

  21. Schieffer KM, Chuang CH, Connor J, Pawelczyk JA, Sekhar DL (2017) Association of iron Deficiency anaemia with hearing loss in US adults. JAMA Otolaryngol 143(4):350–354

    Google Scholar 

  22. Kahlon N, Gandhi A, Mondal S, Narayan S (2011) Effect of iron Deficiency anaemia on audiovisual reaction time in adolescent girls. Indian J Physiol Pharmacol 55(1):53–59

    CAS  PubMed  Google Scholar 

  23. Schieffer KM, Connor JR, Pawelczyk JA, Sekhar DL (2017) The relationship between iron Deficiency anaemia and sensorineural hearing loss in the pediatric and adolescent population. Am J Audiol 26(2):155–162. https://doi.org/10.1044/2017_AJA-16-0093

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of ENT, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, 603103, Tamil Nadu, India

    Prabakaran S., Adithya V., Namasivaya Navin R.B. & Rajasekaran S.

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  1. Prabakaran S.
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  2. Adithya V.
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  3. Namasivaya Navin R.B.
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  4. Rajasekaran S.
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Correspondence to Namasivaya Navin R.B..

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S., P., V., A., R.B., N.N. et al. Pure Tone Audiometry in Anemia Patients. Indian J Otolaryngol Head Neck Surg 76, 1711–1715 (2024). https://doi.org/10.1007/s12070-023-04388-8

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  • DOI: https://doi.org/10.1007/s12070-023-04388-8

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