Abstract
The study was carried out to correlate the inflammatory markers (NLR, ELR, PLR) before and after endoscopic sinus surgery and their role in the prediction of recurrent nasal polyps. This was a hospital-based observational study carried out the 43 patients, aged between 18-45 years, admitted to the department of ENT with CRSwNP and underwent endoscopic sinus surgery. NLR, ELR & PLR values were compared for each patient and calculated from complete blood counts taken before and after surgery follow-up period at post-op 1st week, 3rd week, 3rd month, and 6th month. In our study, 12 out of 43 patients who underwent ESS showed recurrence. The mean value of ELR was higher in the pre-operative and post-operative 1st week in recurrent nasal polyp patients than in non-recurrent nasal polyps. (p-value < 0.05) but there were no significant changes in ELR values in subsequent follow-ups. There were no significant changes in NLR & PLR in the pre-operative and post-operative periods. Although recurrence was common in CRSwNP after endoscopic sinus surgery. Inflammatory markers could be used to predict the chances of recurrence. In our study, ELR is a better parameter than NLR and PLR in the assessment of the chance of recurrence.
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Acknowledgements
I express my sincere and deepest gratitude to my esteemed teacher, mentor, and Chief Supervisor Prof. (Dr.) Sachin Jain sir, Dr. Shivendra Pratap Singh sir, and Dr. Sankalp Keshari sir have been a constant source of encouragement and enthusiasm, not only during this thesis project but also during my master’s program. His expertise, valuable suggestions, constant encouragement, affectionate gratitude, understanding, patience, and healthy criticism added considerably to my experience. Without his continual inspiration, it would have not been possible to complete my thesis as well as my master’s program. I sincerely express my gratitude from the core of my heart to my patients for their cooperation and trust, without whose cooperation the work would not have materialized.
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Singh, S.P., Jain, S., Keshari, S. et al. Comparison of Inflammatory Markers for Prediction of Recurrence of Nasal Polyp after Functional Endoscopy Sinus Surgery. Indian J Otolaryngol Head Neck Surg 75, 3596–3601 (2023). https://doi.org/10.1007/s12070-023-04062-z
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DOI: https://doi.org/10.1007/s12070-023-04062-z