Abstract
Spindle cell neoplasm of the tonsil are rare (Minami et al. in Am J Otolaryngol 29(2):123–125, 2008) and can be difficult to diagnose due to their non-specific clinical presentation and histological characteristics (Su et al. in J Chin Med Assoc 69(10):478–483, 2006). Differential diagnoses include lymphoma and squamous cell carcinoma (Hyams in Clin Otolaryngol Allied Sci 3(2):117–126, 1978). Oropharyngeal spindle cell neoplasms were more likely to occur in the tongue base and tonsil (58%) (Gerry et al. in Ann Otol Rhinol Laryngol 123(8):576–583, 2014). In this article, we report a case of tonsillar spindle cell neoplasm which is extremely rare.
Similar content being viewed by others
References
Minami SB, Shinden S, Yamashita T (2008) Spindle cell carcinoma of the palatine tonsil: report of a diagnostic pitfall and literature review. Am J Otolaryngol 29(2):123–125
Su HH, Chu ST, Hou YY, Chang KP, Chen CJ (2006) Spindle cell carcinoma of the oral cavity and oropharynx: factors affecting outcome. J Chin Med Assoc 69(10):478–483
Hyams VJ (1978) Differential diagnosis of neoplasia of the palatine tonsil. Clin Otolaryngol Allied Sci 3(2):117–126
Gerry D, Fritsch VA, Lentsch EJ (2014) Spindle cell carcinoma of the upper aerodigestive tract: an analysis of 341 cases with comparison to conventional squamous cell carcinoma. Ann Otol Rhinol Laryngol 123(8):576–583
Magro G, Bisceglia M, Michal M, Eusebi V (2002) Spindle cell lipoma-like tumor, solitary fibrous tumor and myofibroblastoma of the breast: a clinico-pathological analysis of 13 cases in favour of a unifying histogenetic concept. Virchows Arch 440:249–260
Heim-Hall J, Yohe SL (2008) Application of immunohistochemistry to soft tissue neoplasms. Arch Pathol Lab Med 132(3):476–489
Darby IA, Laverdet B, Bonté F, Desmoulière A (2014) Fibroblasts and myofibroblasts in wound healing. Clin Cosmet Investiga Dermatol 7:301–311
Mentzel T, Dry S, Katenkamp D, Fletcher CD (1998) Low-grade myofibroblastic sarcoma: analysis of 18 cases in the spectrum of myofibroblastic tumors. Am J Surg Pathol 22(10):1228–1238
Fisher C (2004) Myofibrosarcoma. Virchows 445:215–223
Demarosi F, Bay A, Moneghini L, Carrassi A (2009) Low-grade myofibroblastic sarcoma of the oral cavity. Oral Surgery Oral Med Oral Pathol Oral Radiol Endodontol 108(2):248–254
LaVigne AW, Meredith DM, D’Adamo DR, Margalit DN (2018) Treatment-refractory ALK-positive inflammatory myofibroblastic tumour of the oral cavity. Case Rep 2018:bcr-2017
Sarma A, Das R, Sharma JD, Kataki AC (2012) Spindle cell carcinoma of the head and neck: a clinicopathological and immunohistochemical study of 40 cases. J Cancer Therapy 3(6):1055–1059
Leonardi E, Dalri P, Pusiol T, Valdagni R, Piscioli F (1986) Spindle-cell squamous carcinoma of head and neck region: a clinicopathologic and immunohistochemical study of eight cases. ORL 48(5):275–281
Funding
No funding received.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
There is no conflict of interest regarding the publication of this Case Report.
Ethical approval
Ethical approval not needed in case report.
Informed consent
Informed consent taken from patient.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Babu, A., Sahni, M., Lakhera, K.K. et al. Unusual Presentation of Tonsillar Spindle Cell Neoplasm: A Case Report. Indian J Otolaryngol Head Neck Surg 75, 3910–3911 (2023). https://doi.org/10.1007/s12070-023-03935-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12070-023-03935-7