SpringerLink
Log in

Successful bilateral lung transplantation after prolonged ECMO support for aspiration pneumonia in a 79-year-old man

  • Case report
  • Published:
Indian Journal of Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Aspiration pneumonia is a serious problem in the elderly due to weakened swallowing reflexes or underlying gastroesophageal reflux disease (GERD). This can lead to acute respiratory distress syndrome (ARDS), which can become life-threatening, sometimes requiring extra corporeal membrane oxygenation (ECMO) support. Lung transplantation is a possible therapeutic option for patients with no signs of lung recovery despite prolonged ECMO support. However, this can be a particularly challenging situation in a geriatric population. We report the case of a 79-year-old male with aspiration pneumonia leading to severe ARDS who underwent successful bilateral lung transplantation after 60 days of ECMO support.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Data availability

The data supporting the findings of this study will be made available from the corresponding author upon reasonable request.

References

  1. Bice T, Maguire J, Caldwell M, Carson SS. Evaluation of the relationship between gastroesophageal reflux disease and the acute respiratory distress syndrome. In: B47. Acute respiratory distress syndrome, pp A3080–A3080. American Thoracic Society. 2014.

  2. Thomas B, Guangxi L, Javier F, **n Q, Rajanigandha D, Sweta T, et al. Prevalence of recurrent acute respiratory distress syndrome (ARDS) and associated factors: a population-based cohort study from 1999 to 2008. Chest. 2009;136:76.

    Article  Google Scholar 

  3. Friedrichson B, Mutlak H, Zacharowski K, Piekarski F. Insight into ECMO, mortality and ARDS: a nationwide analysis of 45,647 ECMO runs. Crit Care. 2021;25:38.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Harano T, Ryan JP, Chan EG, Noda K, Morrel MR, Luketich JD, et al. Lung transplantation for the treatment of irreversible acute respiratory distress syndrome. Clin Transplant. 2021;35:e14182.

    Article  CAS  PubMed  Google Scholar 

  5. Baek MS, Chung CR, Kim HJ, Cho WH, Cho YJ, Park S, et al. Age is major factor for predicting survival in patients with acute respiratory failure on extracorporeal membrane oxygenation: a Korean multicenter study. J Thorac Dis. 2018;10:1406–17.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Cho WH, Kim DW, Yeo HJ, Yoon S, Lee SE, Jeon D, et al. Clinical characteristics of respiratory extracorporeal life support in elderly patients with severe acute respiratory distress syndrome. Acute and Crit Care. 2014;29:266–72.

    Google Scholar 

  7. Hayanga JA, Murphy E, Girgis RE, Jansma S, Khaghani A. Extracorporeal membrane oxygenation as a bridge to lung transplantation in patients over age 70 years: a case report. Transplant Proc. 2017;49:218–20.

    Article  CAS  PubMed  Google Scholar 

  8. Kim EJ, Paik HC, Park MS, Kim MH, Koh SO, Lee YJ, et al. One hundred seven days of ECMO as a bridge to lung transplantation: the longest duration among elderly patients. Acute Crit Care. 2014;29:48–51.

    Google Scholar 

Download references

Acknowledgements

The authors would like to thank the Institute of Heart and Lung Transplantation & Mechanical Circulatory Support, MGM Healthcare Pvt. Ltd., Chennai, India, for their support in managing this patient.

Funding

None.

Author information

Authors and Affiliations

  1. Institute of Heart and Lung Transplantation & Mechanical Circulatory Support, MGM Healthcare, Nelson Manickam Road, Aminjikarai, Chennai, Tamil Nadu, India, 600029

    Sureshkumaran Kandasami, Komarakshi Rajagopalan Balakrishnan, Suresh Rao Kemundel Genny, Murali Krishna Tanguturu, Senthil Kumar Devarajan, Deepika Ramachandran, Soumitra Sinha Roy & Apar **dal

Authors
  1. Sureshkumaran Kandasami
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Komarakshi Rajagopalan Balakrishnan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Suresh Rao Kemundel Genny
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Murali Krishna Tanguturu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Senthil Kumar Devarajan
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Deepika Ramachandran
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Soumitra Sinha Roy
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Apar **dal
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Sureshkumaran Kandasami — writing the original manuscript, formal analysis.

Komarakshi Rajagopalan Balakrishnan — writing the review and editing, supervision.

Suresh Rao Kemundel Genny — supervision.

Murali Krishna Tanguturu — sequence alignment.

Senthil Kumar Devarajan — assisted in manuscript preparation.

Deepika Ramachandran — assisted in manuscript preparation.

Soumitra Sinha Roy — assisted in manuscript preparation.

Apar **dal — assisted in manuscript preparation.

Corresponding author

Correspondence to Sureshkumaran Kandasami.

Ethics declarations

Ethics approval

Not applicable.

Consent

Not applicable.

Conflict of interest

The authors declare there is no potential conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kandasami, S., Balakrishnan, K.R., Genny, S.R.K. et al. Successful bilateral lung transplantation after prolonged ECMO support for aspiration pneumonia in a 79-year-old man. Indian J Thorac Cardiovasc Surg (2024). https://doi.org/10.1007/s12055-024-01749-y

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s12055-024-01749-y

Keywords

Search

Navigation