Log in

Fast-tracking with continuous thoracic epidural analgesia in paediatric congenital heart surgeries: an institutional experience

  • Original Article
  • Published:
Indian Journal of Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Objective

To assess the success of fast-tracking in infants and small children undergoing paediatric cardiac surgery under general anaesthesia with continuous thoracic epidural analgesia (TEA).

Methodology

It is a retrospective study at a tertiary care hospital. A total of 461 children, aged 12 years or younger, were operated for congenital heart disease over a 2-year period from January 2018 to December 2019. After the exclusion of 71 patients, data from the remaining 390 patients were analysed.

Measurements and main results

The median time for extubation after intensive care unit admission was 2 h and 25 min (0–20 h). Extubation within 6 h was achieved in 215 patients (~ 55%). Patients in the early extubation group had significantly shorter hospital stay (4.1 ± 2.3 vs 6.9 ± 3.9 days, p = 0.004) than patients in the ventilated group. Reintubation was required in 27 (6.9%) patients. Thirteen patients died postoperatively on ventilator. Patients with low nadir temperature intraoperatively and cardiopulmonary bypass time > 90 min significantly predicted failure in fast-tracking with an odds ratio (OR) = 1.27; CI: 1.18–1.38 and OR = 2.3; CI: 1.8–2.96 respectively. The Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery Congenital Heart Surgery mortality score, younger age, Down syndrome and high vasopressor inotropic score did not adversely affect early extubation, contrary to contemporary concerns.

Conclusions

A multimodal approach for perioperative pain relief and sedation consisting of propofol and dexmedetomidine infusion along with TEA ensures early extubation in 59% of the cases undergoing paediatric cardiac surgery. Our data suggests that fast-tracking is feasible with safe and superior outcomes in a subset of appropriate patients undergoing paediatric cardiac surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price includes VAT (United Kingdom)

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Mittnacht AJC, Hollinger I. Fast-tracking in pediatric cardiac surgery – the current standing. Ann Card Anaesth. 2010;13:92–101.

    Article  Google Scholar 

  2. Mittnacht AJC, Thanjan M, Srivastava S, et al. Extubation in the operating room after congenital heart surgery in children. J Thorac Cardiovasc Surg. 2008;136:88–93.

    Article  Google Scholar 

  3. Neirotti RA, Jones D, Hackbarth R, Fosse GP. Early extubation in congenital heart surgery. Heart Lung Circ. 2002;11:157–61.

    Article  Google Scholar 

  4. Heinle JS, Diaz LK, Fox LS. Early extubation after cardiac operations in neonates and young infants. J Thoracic Cardiovasc Surg. 1997;114:413–8.

    Article  CAS  Google Scholar 

  5. Székely A, Sápi E, Király L, Szatmári A, Dinya E. Intraoperative and postoperative risk factors for prolonged mechanical ventilation after pediatric cardiac surgery. Paediatr Anaesth. 2006;16:1166–75.

    PubMed  Google Scholar 

  6. Leyvi G, Taylor DG, Reith E, Stock A, Crooke G, Wasnick JD. Caudal anesthesia in pediatric cardiac surgery: Does it affect outcome? J Cardiothorac Vasc Anesth. 2005;19:734–8.

    Article  Google Scholar 

  7. Tenenbein PK, Debrouwere R, Maguire D, et al. Thoracic epidural analgesia improves pulmonary function in patients undergoing cardiac surgery. Can J Anaesth. 2008;55:344–50.

    Article  Google Scholar 

  8. Hammer GB, Ngo K, Macario A. A retrospective examination of regional plus general anesthesia in children undergoing open heart surgery. Anesth Analg. 2000;90:1020–4.

    Article  CAS  Google Scholar 

  9. Peterson KL, DeCampli WM, Pike NA, Robbins RC, Reitz BA. A report of two hundred twenty cases of regional anesthesia in pediatric cardiac surgery. Anesth Analg. 2000;90:1014–9.

    Article  CAS  Google Scholar 

  10. Teyin E, Derbent A, Balcioglu T, Cokmez B. The efficacy of caudal morphine or bupivacaine combined with general anesthesia on postoperative pain and neuroendocrine stress response in children. Paediatr Anaesth. 2006;16:290–6.

    Article  Google Scholar 

  11. Kowalewski R, Seal D, Tang T, Prusinkiewicz C, Ha D. Neuraxial anesthesia for cardiac surgery: thoracic epidural and high spinal anesthesia - why is it different? HSR Proc Intensive Care Cardiovasc Anesth. 2011;3:25–8.

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Merkel SI, Voepel-Lewis T, Shayevitz JR, Malviya S. The FLACC: a behavioral scale for scoring postoperative pain in young children. Pediatr Nurs. 1997;23:293–7.

    CAS  PubMed  Google Scholar 

  13. Davidson J, Tong S, Hancock H, Hauck A, da Cruz E, Kaufman J. Prospective validation of the vasoactive- inotropic score and correlation to short-term outcomes in neonates and infants after cardiothoracic surgery. Intensive Care Med. 2012;38:1184–90.

    Article  Google Scholar 

  14. Jacobs ML, Jacobs JP, Thibault D, et al. Updating an empirically based tool for analyzing congenital heart surgery mortality. World J Pediatr Congenit Heart Surg. 2021;12:246–81.

    Article  Google Scholar 

  15. Cray SH, Holtby HM, Kartha VM, Cox PN, Roy WL. Early tracheal extubation after paediatric cardiac surgery: the use of propofol to supplement low-dose opioid anaesthesia. Paediatr Anaesth. 2001;11:465–71.

    Article  CAS  Google Scholar 

  16. El-Morsy GZ, Elgamal AF. Dexmedetomidine; an adjuvant drug for fast track technique in pediatric cardiac surgery. Egypt J Anaesth. 2014;30:347–51.

    Article  Google Scholar 

  17. Sharma VK, Kumar G, Joshi S, Tiwari N, Kumar V, Ramamurthy HR. An evolving anesthetic protocol fosters fast tracking in pediatric cardiac surgery: a comparison of two anesthetic techniques. Ann Pediatr Cardiol. 2020;13:31–7.

    Article  Google Scholar 

  18. Davis S, Worley S, Mee RBB, Harrison AM. Factors associated with early extubation after cardiac surgery in young children. Pediatr Crit Care Med. 2004;5:63–8.

    Article  Google Scholar 

  19. Harrison AM, Cox AC, Davis S, Piedmonte M, Drummond-Webb JJ, Mee RBB. Failed extubation after cardiac surgery in young children: prevalence, pathogenesis, and risk factors. Pediatr Crit Care Med. 2002;3:148–52.

    Article  Google Scholar 

  20. Vida VL, Leon-Wyss J, Rojas M, Mack R, Barnoya J, Castañeda AR. Pulmonary artery hypertension: is it really a contraindicating factor for early extubation in children after cardiac surgery? Ann Thorac Surg. 2006;81:1460–5.

    Article  Google Scholar 

  21. Preisman S, Lembersky H, Yusim Y, et al. A randomized trial of outcomes of anesthetic management directed to very early extubation after cardiac surgery in children. J Cardiothorac Vasc Anesth. 2009;23:348–57.

    Article  Google Scholar 

  22. Manrique AM, Feingold B, Di Filippo S, Orr RA, Kuch BA, Munoz R. Extubation after cardiothoracic surgery in neonates, children, and young adults: One year of institutional experience. Pediatr Crit Care Med. 2007;8:552–5.

    Article  Google Scholar 

Download references

Acknowledgements

We thank Dr. (Brig) Vipul Sharma, Professor (Cardiac Anaesthesiologist), Dr. DY Patil Medical College, Pune, for formulating the fast-track protocol in the organisation over the years and guiding us in safe practice of paediatric cardiac surgery. Thank you.

Funding

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alok Kumar.

Ethics declarations

Ethical committee approval

Institutional Ethical Clearance obtained.

CTRI NO CTRI/2022/01/039585.

Prior publication

Nil.

Informed consent

Not applicable (retrospective study).

Conflict of interest

None.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Supplementary file1

(DOCX 4,603 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kumar, A., Ramamurthy, H.R., Tiwari, N. et al. Fast-tracking with continuous thoracic epidural analgesia in paediatric congenital heart surgeries: an institutional experience. Indian J Thorac Cardiovasc Surg 38, 469–480 (2022). https://doi.org/10.1007/s12055-022-01373-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12055-022-01373-8

Keywords

Navigation