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The Brain: Is it a Next Frontier to Better Understand the Regulation and Control of Hematopoiesis for Future Modulation and Treatment?

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Abstract

We wish to suggest the possibility there is a link between the brain and hematopoiesis in the bone marrow and that in the future it may be possible to use such information for better understanding of the regulation of hematopoiesis, and for efficacious treatment of hematopoietic disorders.

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Acknowledgements

Much of the work done in the Broxmeyer lab was supported by the following US Public Health Grants to him: R35 HL139599 (Outstanding Investigator Award) and U54 DK106846 (Cooperative Center of Excellence in Hematology, CCEH). The first author would like to thank the Director of the New York Blood Center, Dr. Christopher Hillyer, for sending him the book: “When Einstein Walked with Gödel” as a thank you for consulting at the time for the New York Blood Center Research Program. It was the third chapter in the book that got Dr. Broxmeyer thinking about this present project.

Funding

Much of the work done in the Broxmeyer lab was supported by the following US Public Health Grants to him: R35 HL139599 (Outstanding Investigator Award) and U54 DK106846 (Cooperative Center of Excellence in Hematology, CCEH).

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Authors and Affiliations

  1. Department of Microbiology and Immunology, Indiana University School of Medicine, 950 West Walnut Street, R2 Bldg, Room 302, Indianapolis, IN, 46202-5181, USA

    Hal E. Broxmeyer & Scott H. Cooper

  2. Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, 46202, USA

    Karmen K. Yoder, Yu-Chien Wu & Gary D. Hutchins

  3. Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA

    Sherif S. Farag

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  1. Hal E. Broxmeyer
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Correspondence to Hal E. Broxmeyer.

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Broxmeyer, H.E., Yoder, K.K., Wu, YC. et al. The Brain: Is it a Next Frontier to Better Understand the Regulation and Control of Hematopoiesis for Future Modulation and Treatment?. Stem Cell Rev and Rep 17, 1083–1090 (2021). https://doi.org/10.1007/s12015-021-10203-0

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