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Predictors of Osteoarthritis Pain: the Importance of Resilience

  • Chronic Pain (R Staud, Section Editor)
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Abstract

Purpose of Review

Osteoarthritis (OA) is one of the most common and disabling forms of arthritis worldwide, with joint pain being a primary symptom. Given that clinical symptoms often show poor concordance with tissue damage in OA, processes other than joint remodeling likely play a role in the condition. Using the biopsychosocial model of pain as a guiding framework, the purpose of this review is to highlight the extra-articular mechanisms that contribute to pain and dysfunction in OA, with a specific focus on resilience.

Recent Findings

Whereas previous research has mostly focused on risk factors for worsening of OA pain, recently emerging evidence places greater emphasis on the identification of protective mechanisms that enhance pain adaptation and palliate the negative effects of joint pain.

Summary

In view of this new and important research, more emphasis should be placed on endogenous pain modulation and, in particular, pain attenuation. The result of such work could serve as a basis for optimizing treatment in the OA population.

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Acknowledgments

Preparation of the article was supported by the National Institutes of Health/National Institute on Aging (K99AG052642) awarded to EJB.

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Authors and Affiliations

  1. Department of Community Dentistry and Behavioral Science, Pain Research & Intervention Center of Excellence, University of Florida, 1395 Center Drive, Room D2-13, PO Box 100404, Gainesville, FL, 32610, USA

    Emily J. Bartley

  2. The University of Tulsa, Department of Psychology, 800 South Tucker Drive, Tulsa, OK, 74104, USA

    Shreela Palit

  3. College of Medicine, Pain Research & Intervention Center of Excellence, University of Florida, PO Box 100221, Gainesville, FL, 32610, USA

    Roland Staud

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  1. Emily J. Bartley
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Correspondence to Emily J. Bartley.

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Dr. Bartley reports grants from National Institutes of Health/ National Institute on Aging, during the conduct of the study.

Shreela Palit and Roland Staud declare that they have no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Chronic Pain

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Bartley, E.J., Palit, S. & Staud, R. Predictors of Osteoarthritis Pain: the Importance of Resilience. Curr Rheumatol Rep 19, 57 (2017). https://doi.org/10.1007/s11926-017-0683-3

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  • DOI: https://doi.org/10.1007/s11926-017-0683-3

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