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Séquelles cognitives chez les patients traités pour une leucémie aiguë lymphoblastique pendant l’enfance

Cognitive impairment of leukemia and its treatment in childhood

  • Article Original / Original Article
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Psycho-Oncologie

Résumé

Dans notre expérience clinique, certains enfants traités pour une leucémie aiguë lymphoblastique décrivent des troubles cognitifs, notamment mnésiques, ce qui nous a amenés à réaliser une revue de la littérature sur les séquelles cognitives chez ces patients. La radiothérapie et la chimiothérapie entraîneraient des séquelles aux niveaux attentionnel, exécutif et mnésique chez certains patients. Des recherches restent à mener pour spécifier les séquelles en fonction des protocoles thérapeutiques et adapter les prises en charge.

Abstract

In our experience, some children treated for leukemia describe cognitive impairment including memory disorders, which led us to conduct a literature review on cognitive sequelae in such patients. Radiotherapy and chemotherapy would be responsible for specific cognitive sequelae, particularly at attentional, executive, and mnemonic levels in some patients. Researches remain to be done to describe these disorders more accurately and to adapt patient care.

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Authors and Affiliations

  1. Université Paris-VIII, F-93526, Saint-Denis, France

    S. Vanwalleghem

  2. Service d’Immuno-Hématologie pédiatrique, APHP, hôpital Robert Debré, 48, boulevard Sérurier, F-75019, Paris, France

    A. Haggège-Bonnefont & T. Leblanc

Authors
  1. S. Vanwalleghem
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  2. A. Haggège-Bonnefont
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  3. T. Leblanc
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Corresponding author

Correspondence to A. Haggège-Bonnefont.

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Vanwalleghem, S., Haggège-Bonnefont, A. & Leblanc, T. Séquelles cognitives chez les patients traités pour une leucémie aiguë lymphoblastique pendant l’enfance. Psycho Oncologie 10, 284–288 (2016). https://doi.org/10.1007/s11839-016-0602-2

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  • DOI: https://doi.org/10.1007/s11839-016-0602-2

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