Abstract
Purpose
The short-term outcome of physiologic repair for congenitally corrected transposition of the great arteries (ccTGA) is generally considered favorable; however, the long-term outcome is the greatest problem, especially with regard to right ventricular (RV) function and tricuspid regurgitation (TR). Although tricuspid valve replacement (TVR) appears to be a realistic choice for treating severe TR, determining the timing of TVR may be difficult.
Methods
We carried out a retrospective analysis of the long-term outcomes of physiologic repair for ccTGA focusing on patients with TVR. The study involved 23 patients after physiologic repair 10 or more years prior. There were 9 TVR cases in 5 pediatric patients (before age 18) and 4 adult patients.
Results
There were two late deaths; however, there was no case related with cardiac events. Overall survival at 10 and 20 years were 95.5 and 90.2 %, respectively, and 7 of 8 patients after TVR were NYHA class I or II. No patient has presented postoperative complications in the form of bleeding or embolism after TVR with mechanical valve.
Conclusions
An analysis of the results of physiologic repair for ccTGA showed that the long-term outcome was overall favorable. To maintain RV function, early TVR may be a reasonable option, even in the management of patients during childhood.
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All the authors have declared no competing interest. None of the authors of this manuscript has any financial of personal relationship with other people or organization that could inappropriately influence their work.
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Hirose, K., Nishina, T., Kanemitsu, N. et al. The long-term outcomes of physiologic repair for ccTGA (congenitally corrected transposition of the great arteries). Gen Thorac Cardiovasc Surg 63, 496–501 (2015). https://doi.org/10.1007/s11748-015-0550-y
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DOI: https://doi.org/10.1007/s11748-015-0550-y