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Maladie de Verneuil : épidémiologie, signes cliniques, qualité de vie et comorbidités

Verneuil’s disease : Epidemiology, clinical signs, quality of life and comorbidities

  • Dossier Thématique / Thematic File
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Côlon & Rectum

Résumé

La maladie de Verneuil ou hidrosadénite suppurée est considérée comme une maladie orpheline, pourtant elle est loin d’être rare. C’est une affection chronique des glandes sudoripares apocrines. Elle se manifeste par des lésions douloureuses, profondes, à type de nodules, de clapiers purulents et d’abcès. Le diagnostic est souvent tardif. Des associations morbides sont décrites avec la maladie de Crohn, la spondylarthrite ankylosante, la maladie pilonidale et des affections dermatologiques. La maladie altère significativement la qualité de vie. La physiopathologie de la maladie est complexe, associant des facteurs génétiques, environnementaux (tabac, obésité) et une dysrégulation du système immunitaire au niveau du follicule pileux.

Abstract

Verneuil’s disease or hidradenitis is considered as an orphan’s disesase, although it is not uncommon. It is an inflammatory and suppurating chronic condition develo** on skin areas with apocrine glands. It causes painful sores, deep type nodules, abscesses and pus discharge. The diagnosis is often delayed. Morbid associations are described with Crohn’s disease, ankylosing spondylitis, pilonidal disease and dermatologic diseases. The disease significantly affects the quality of life. The pathophysiology of the disease is a complex combination of genetic, environmental (tobacco, obesity) factors and dysregulation of the immune system of the hair follicle.

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    A. Senéjoux

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Senéjoux, A. Maladie de Verneuil : épidémiologie, signes cliniques, qualité de vie et comorbidités. Colon Rectum 10, 100–104 (2016). https://doi.org/10.1007/s11725-016-0633-7

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  • DOI: https://doi.org/10.1007/s11725-016-0633-7

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