Abstract
Cadmium (Cd) pollution has become a global environmental issue because Cd gets easily accumulated and translocated in the food chain, threatening human health. Considering the detrimental effects and non-biodegradability of environmental Cd, this is an urgent issue that needs to be addressed through the development of robust, cost-effective, and eco-friendly green routes for monitoring and remediating toxic levels of Cd. This article attempts to review various bacterial approaches toward biosensing and bioremediation of Cd in the environment. This review focuses on the recent development of bacterial cell-based biosensors for the detection of bioavailable Cd and the bioremediation of toxic Cd by natural or genetically-engineered bacteria. The present limitations and future perspectives of these available bacterial approaches are outlined. New trends for integrating synthetic biology and metabolic engineering into the design of bacterial biosensors and bioadsorbers are additionally highlighted.
Graphical abstract
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abbas SZ, Rafatullah M, Ismail N, Lalung J (2014) isolation, identification, and characterization of cadmium resistant Pseudomonas sp. M3 from industrial wastewater. J Waste Manag 2014:160398. https://doi.org/10.1155/2014/160398
Al-Dhabi NA, Esmail GA, Mohammed Ghilan AK, Valan Arasu M (2019) Optimizing the management of cadmium bioremediation capacity of metal-resistant Pseudomonas sp. strain Al-Dhabi-126 isolated from the industrial city of saudi arabian environment. Int J Environ Res Public Health. https://doi.org/10.3390/ijerph16234788
Ansari MI, Malik A (2007) Biosorption of nickel and cadmium by metal resistant bacterial isolates from agricultural soil irrigated with industrial wastewater. Bioresour Technol 98:3149–3153. https://doi.org/10.1016/j.biortech.2006.10.008
Bae W, Chen W, Mulchandani A, Mehra RK (2000) Enhanced bioaccumulation of heavy metals by bacterial cells displaying synthetic phytochelatins. Biotechnol Bioeng 70:518–524
Bae W, Mulchandani A, Chen W (2002) Cell surface display of synthetic phytochelatins using ice nucleation protein for enhanced heavy metal bioaccumulation. J Inorg Biochem 88:223–227. https://doi.org/10.1016/s0162-0134(01)00392-0
Balali-Mood M, Naseri K, Tahergorabi Z, Khazdair MR, Sadeghi M (2021) Toxic mechanisms of five heavy metals: mercury, lead, chromium, cadmium, and arsenic. Front Pharmacol 12:643972. https://doi.org/10.3389/fphar.2021.643972
Bereza-Malcolm L, Aracic S, Kannan R, Mann G, Franks AE (2017) Functional characterization of Gram-negative bacteria from different genera as multiplex cadmium biosensors. Biosens Bioelectron 94:380–387. https://doi.org/10.1016/j.bios.2017.03.029
Bereza-Malcolm LT, Mann G, Franks AE (2015) Environmental sensing of heavy metals through whole cell microbial biosensors: a synthetic biology approach. ACS Synth Biol 4:535–546. https://doi.org/10.1021/sb500286r
Biondo R, da Silva FA, Vicente EJ, Souza Sarkis JE, Schenberg AC (2012) Synthetic phytochelatin surface display in Cupriavidus metallidurans CH34 for enhanced metals bioremediation. Environ Sci Technol 46:8325–8332. https://doi.org/10.1021/es3006207
Biran I, Babai R, Levcov K, Rishpon J, Ron EZ (2000) Online and in situ monitoring of environmental pollutants: electrochemical biosensing of cadmium. Environ Microbiol 2:285–290. https://doi.org/10.1046/j.1462-2920.2000.00103.x
Brocklehurst KR, Hobman JL, Lawley B, Blank L, Marshall SJ, Brown NL, Morby AP (1999) ZntR is a Zn(II)-responsive MerR-like transcriptional regulator of zntA in Escherichia coli. Mol Microbiol 31:893–902. https://doi.org/10.1046/j.1365-2958.1999.01229.x
Cavet JS, Meng W, Pennella MA, Appelhoff RJ, Giedroc DP, Robinson NJ (2002) A nickel-cobalt-sensing ArsR-SmtB family repressor. Contributions of cytosol and effector binding sites to metal selectivity. J Biol Chem 277:38441–38448. https://doi.org/10.1074/jbc.M207677200
Cayron J, Effantin G, Prudent E, Rodrigue A (2020) Original sequence divergence among Pseudomonas putida CadRs drive specificity. Res Microbiol 171:21–27. https://doi.org/10.1016/j.resmic.2019.11.001
Chakraborty J, Das S (2014) Characterization and cadmium-resistant gene expression of biofilm-forming marine bacterium Pseudomonas aeruginosa JP-11. Environ Sci Pollut Res Int 21:14188–14201. https://doi.org/10.1007/s11356-014-3308-7
Chellaiah ER (2018) Cadmium (heavy metals) bioremediation by Pseudomonas aeruginosa: a minireview. Appl Water Sci 8:154. https://doi.org/10.1007/s13201-018-0796-5
Chen PR, He C (2008) Selective recognition of metal ions by metalloregulatory proteins. Curr Opin Chem Biol 12:214–221. https://doi.org/10.1016/j.cbpa.2007.12.010
Chen SY, Wei W, Yin BC, Tong Y, Lu J, Ye BC (2019) Development of a highly sensitive whole-cell biosensor for arsenite detection through engineered promoter modifications. ACS Synth Biol 8:2295–2302. https://doi.org/10.1021/acssynbio.9b00093
Choppala G, Saifullah BN, Bibi S, Iqbal M, Rengel Z, Kunhikrishnan A, Ashwath N, Ok YS (2014) Cellular mechanisms in higher plants governing tolerance to cadmium toxicity. Crit Rev Plant Sci 33:374–391. https://doi.org/10.1080/07352689.2014.903747
Ebrahimi M, Raoof JB, Ojani R (2018) Design of an electrochemical DNA-based biosensor for selective determination of cadmium ions using a DNA hybridization indicator. Int J Biol Macromol 108:1237–1241. https://doi.org/10.1016/j.ijbiomac.2017.11.023
EC (1998) Quality of water intended for human consumption. Brussels, Belgium
Endo G, Silver S (1995) CadC, the transcriptional regulatory protein of the cadmium resistance system of Staphylococcus aureus plasmid pI258. J Bacteriol 177:4437–4441. https://doi.org/10.1128/jb.177.15.4437-4441.1995
Fowler BA (2009) Monitoring of human populations for early markers of cadmium toxicity: a review. Toxicol Appl Pharmacol 238:294–300. https://doi.org/10.1016/j.taap.2009.05.004
Gireesh-Babu P, Chaudhari A (2012) Development of a broad-spectrum fluorescent heavy metal bacterial biosensor. Mol Biol Rep 39:11225–11229. https://doi.org/10.1007/s11033-012-2033-x
Guo Y, Hui CY, Liu L, Chen MP, Huang HY (2021) Development of a bioavailable Hg(II) sensing system based on MerR-regulated visual pigment biosynthesis. Sci Rep 11:13516. https://doi.org/10.1038/s41598-021-92878-6
Guo Y, Hui CY, Liu L, Zheng HQ, Wu HM (2019) Improved monitoring of low-level transcription in Escherichia coli by a beta-galactosidase alpha-complementation system. Front Microbiol 10:1454. https://doi.org/10.3389/fmicb.2019.01454
Guo Y, Hui CY, Zhang NX, Liu L, Li H, Zheng HJ (2021) Development of cadmium multiple-signal biosensing and bioadsorption systems based on artificial cad operons. Front Bioeng Biotechnol 9:585617. https://doi.org/10.3389/fbioe.2021.585617
Gupta N, Renugopalakrishnan V, Liepmann D, Paulmurugan R, Malhotra BD (2019) Cell-based biosensors: recent trends, challenges and future perspectives. Biosens Bioelectron 141:111435. https://doi.org/10.1016/j.bios.2019.111435
Gutiérrez J-C, Amaro F, DÃaz S, MartÃn-González A (2019) Environmental biosensors: a microbiological view. In: Thouand G (ed) Handbook of cell biosensors. Springer International Publishing, Cham, pp 1–22
Hakkila KM, Nikander PA, Junttila SM, Lamminmaki UJ, Virta MP (2011) Cd-specific mutants of mercury-sensing regulatory protein MerR, generated by directed evolution. Appl Environ Microbiol 77:6215–6224. https://doi.org/10.1128/AEM.00662-11
Halttunen T, Salminen S, Tahvonen R (2007) Rapid removal of lead and cadmium from water by specific lactic acid bacteria. Int J Food Microbiol 114:30–35. https://doi.org/10.1016/j.ijfoodmicro.2006.10.040
Hansda A, Kumar V, Anshumali, (2016) A comparative review towards potential of microbial cells for heavy metal removal with emphasis on biosorption and bioaccumulation. World J Microbiol Biotechnol 32:170. https://doi.org/10.1007/s11274-016-2117-1
Haq F, Butt M, Ali H, Chaudhary HJ (2016) Biosorption of cadmium and chromium from water by endophytic Kocuria rhizophila: equilibrium and kinetic studies. Desalin Water Treat 57:19946–19958. https://doi.org/10.1080/19443994.2015.1109561
He X, Chen W, Huang Q (2012) Surface display of monkey metallothionein alpha tandem repeats and EGFP fusion protein on Pseudomonas putida X4 for biosorption and detection of cadmium. Appl Microbiol Biotechnol 95:1605–1613. https://doi.org/10.1007/s00253-011-3768-3
He Y, Ma W, Li Y, Liu J, **g W, Wang L (2014) Expression of metallothionein of freshwater crab (Sinopotamon henanense) in Escherichia coli enhances tolerance and accumulation of zinc, copper and cadmium. Ecotoxicology 23:56–64. https://doi.org/10.1007/s10646-013-1151-0
Hu Q, Qi H, Bai Z, Dou M, Zeng J, Zhang F, Zhang H (2007) Biosorption of cadmium by a Cd2+-hyperresistant Bacillus cereus strain HQ-1 newly isolated from a lead and zinc mine. World J Microbiol Biotechnol 23:971–976. https://doi.org/10.1007/s11274-006-9322-2
Hui C, Guo Y, Zhang W, Gao C, Yang X, Chen Y, Li L, Huang X (2018) Surface display of PbrR on Escherichia coli and evaluation of the bioavailability of lead associated with engineered cells in mice. Sci Rep 8:5685. https://doi.org/10.1038/s41598-018-24134-3
Hui CY, Guo Y, Li LM, Liu L, Chen YT, Yi J, Zhang NX (2021) Indigoidine biosynthesis triggered by the heavy metal-responsive transcription regulator: a visual whole-cell biosensor. Appl Microbiol Biotechnol 105:6087–6102. https://doi.org/10.1007/s00253-021-11441-5
Hui CY, Guo Y, Liu L, Zhang NX, Gao CX, Yang XQ, Yi J (2020a) Genetic control of violacein biosynthesis to enable a pigment-based whole-cell lead biosensor. RSC Adv 10:28106–28113. https://doi.org/10.1039/D0RA04815A
Hui CY, Guo Y, Liu L, Zheng HQ, Gao CX, Zhang W (2020b) Construction of a RFP-lacZalpha bicistronic reporter system and its application in lead biosensing. PLoS One 15:e0228456. https://doi.org/10.1371/journal.pone.0228456
Hui CY, Guo Y, Liu L, Zheng HQ, Wu HM, Zhang LZ, Zhang W (2019) Development of a novel bacterial surface display system using truncated OmpT as an anchoring motif. Biotechnol Lett 41:763–777. https://doi.org/10.1007/s10529-019-02676-4
Hui CY, Guo Y, Wu J, Liu L, Yang XQ, Guo X, **e Y, Yi J (2021b) Detection of bioavailable cadmium by double-color fluorescence based on a dual-sensing bioreporter system. Front Microbiol 12:696195. https://doi.org/10.3389/fmicb.2021.696195
Hui CY, Guo Y, Yang XQ, Zhang W, Huang XQ (2018b) Surface display of metal binding domain derived from PbrR on Escherichia coli specifically increases lead(II) adsorption. Biotechnol Lett 40:837–845. https://doi.org/10.1007/s10529-018-2533-4
Ivask A, Francois M, Kahru A, Dubourguier HC, Virta M, Douay F (2004) Recombinant luminescent bacterial sensors for the measurement of bioavailability of cadmium and lead in soils polluted by metal smelters. Chemosphere 55:147–156. https://doi.org/10.1016/j.chemosphere.2003.10.064
Jia X, Liu T, Ma Y, Wu K (2021) Construction of cadmium whole-cell biosensors and circuit amplification. Appl Microbiol Biotechnol 105:5689–5699. https://doi.org/10.1007/s00253-021-11403-x
Joe MH, Lee KH, Lim SY, Im SH, Song HP, Lee IS, Kim DH (2012) Pigment-based whole-cell biosensor system for cadmium detection using genetically engineered Deinococcus radiodurans. Bioprocess Biosyst Eng 35:265–272. https://doi.org/10.1007/s00449-011-0610-3
Jung J, Lee SJ (2019) Biochemical and biodiversity insights into heavy metal ion-responsive transcription regulators for synthetic biological heavy metal sensors. J Microbiol Biotechnol 29:1522–1542. https://doi.org/10.4014/jmb.1908.08002
Kang SH, Singh S, Kim JY, Lee W, Mulchandani A, Chen W (2007) Bacteria metabolically engineered for enhanced phytochelatin production and cadmium accumulation. Appl Environ Microbiol 73:6317–6320. https://doi.org/10.1128/AEM.01237-07
Kao WC, Chiu YP, Chang CC, Chang JS (2006) Localization effect on the metal biosorption capability of recombinant mammalian and fish metallothioneins in Escherichia coli. Biotechnol Prog 22:1256–1264. https://doi.org/10.1021/bp060067b
Kim HJ, Jeong H, Lee SJ (2018) Synthetic biology for microbial heavy metal biosensors. Anal Bioanal Chem 410:1191–1203. https://doi.org/10.1007/s00216-017-0751-6
Kim HJ, Lim JW, Jeong H, Lee SJ, Lee DW, Kim T, Lee SJ (2016) Development of a highly specific and sensitive cadmium and lead microbial biosensor using synthetic CadC-T7 genetic circuitry. Biosens Bioelectron 79:701–708. https://doi.org/10.1016/j.bios.2015.12.101
Kim SK, Lee BS, Wilson DB, Kim EK (2005) Selective cadmium accumulation using recombinant Escherichia coli. J Biosci Bioeng 99:109–114. https://doi.org/10.1263/jbb.99.109
Komy ZR, Gabar RM, Shoriet AA, Mohammed RM (2006) Characterisation of acidic sites of Pseudomonas biomass capable of binding protons and cadmium and removal of cadmium via biosorption. World J Microbiol Biotechnol 22:975–982. https://doi.org/10.1007/s11274-006-9143-3
Kumar A, Subrahmanyam G, Mondal R, Cabral-Pinto MMS, Shabnam AA, Jigyasu DK, Malyan SK, Fagodiya RK, Khan SA, Kumar A, Yu ZG (2021) Bio-remediation approaches for alleviation of cadmium contamination in natural resources. Chemosphere 268:128855. https://doi.org/10.1016/j.chemosphere.2020.128855
Kumar S, Verma N, Singh A (2017) Development of cadmium specific recombinant biosensor and its application in milk samples. Sens Actuators B Chem 240:248–254
Lee SW, Glickmann E, Cooksey DA (2001) Chromosomal locus for cadmium resistance in Pseudomonas putida consisting of a cadmium-transporting ATPase and a MerR family response regulator. Appl Environ Microbiol 67:1437–1444. https://doi.org/10.1128/AEM.67.4.1437-1444.2001
Lee W, Kim H, Kang Y, Lee Y, Yoon Y (2019) A biosensor platform for metal detection based on enhanced green fluorescent protein. Sensors. https://doi.org/10.3390/s19081846
Li C, Wang H, Liao X, **ao R, Liu K, Bai J, Li B, He Q (2022) Heavy metal pollution in coastal wetlands: a systematic review of studies globally over the past three decades. J Hazard Mater 424:127312. https://doi.org/10.1016/j.jhazmat.2021.127312
Li J, Liu YR, Zhang LM, He JZ (2019) Sorption mechanism and distribution of cadmium by different microbial species. J Environ Manage 237:552–559. https://doi.org/10.1016/j.jenvman.2019.02.057
Li J, Wei X, Yu P, Deng X, Xu W, Ma M, Zhang H (2016) Expression of cadR enhances its specific activity for Cd detoxification and accumulation in Arabidopsis. Plant Cell Physiol 57:1720–1731. https://doi.org/10.1093/pcp/pcw093
Lin X, Mou R, Cao Z, Xu P, Wu X, Zhu Z, Chen M (2016) Characterization of cadmium-resistant bacteria and their potential for reducing accumulation of cadmium in rice grains. Sci Total Environ 569–570:97–104. https://doi.org/10.1016/j.scitotenv.2016.06.121
Liu Q, Yuan F, Liang Y, Li Z (2015) Cadmium adsorption by E. coli with surface displayed CadR. RSC Adv 5:16089–16092. https://doi.org/10.1039/C4RA07805E
Liu T, Golden JW, Giedroc DP (2005) A zinc(II)/lead(II)/cadmium(II)-inducible operon from the Cyanobacterium anabaena is regulated by AztR, an alpha3N ArsR/SmtB metalloregulator. Biochemistry 44:8673–8683. https://doi.org/10.1021/bi050450+
Liu T, Nakashima S, Hirose K, Shibasaka M, Katsuhara M, Ezaki B, Giedroc DP, Kasamo K (2004) A novel cyanobacterial SmtB/ArsR family repressor regulates the expression of a CPx-ATPase and a metallothionein in response to both Cu(I)/Ag(I) and Zn(II)/Cd(II). J Biol Chem 279:17810–17818. https://doi.org/10.1074/jbc.M310560200
Liu X, Hu Q, Yang J, Huang S, Wei T, Chen W, He Y, Wang D, Liu Z, Wang K, Gan J, Chen H (2019) Selective cadmium regulation mediated by a cooperative binding mechanism in CadR. Proc Natl Acad Sci U S A 116:20398–20403. https://doi.org/10.1073/pnas.1908610116
Lm LA, Cavalcanti D, Luna MC, de Lima EST, La Rotta CE, Campos-Takaki GM (2018) Cadmium removal from aqueous solutions by strain of Pantoea agglomerans UCP1320 isolated from laundry effluent. Open Microbiol J 12:297–307. https://doi.org/10.2174/1874285801812010297
Loukidou MX, Karapantsios TD, Zouboulis AI, Matis KA (2004) Diffusion kinetic study of cadmium(II) biosorption by Aeromonas caviae. J Chem Technol Biotechnol 79:711–719. https://doi.org/10.1002/jctb.1043
Lu WB, Shi JJ, Wang CH, Chang JS (2006) Biosorption of lead, copper and cadmium by an indigenous isolate Enterobacter sp. J1 possessing high heavy-metal resistance. J Hazard Mater 134:80–86. https://doi.org/10.1016/j.jhazmat.2005.10.036
Ma N, Cai R, Sun C (2021) Threonine dehydratase enhances bacterial cadmium resistance via driving cysteine desulfuration and biomineralization of cadmium sulfide nanocrystals. J Hazard Mater 417:126102. https://doi.org/10.1016/j.jhazmat.2021.126102
Ma Y, Lin J, Zhang C, Ren Y, Lin J (2011) Cd(II) and As(III) bioaccumulation by recombinant Escherichia coli expressing oligomeric human metallothioneins. J Hazard Mater 185:1605–1608. https://doi.org/10.1016/j.jhazmat.2010.10.051
Magrisso S, Erel Y, Belkin S (2008) Microbial reporters of metal bioavailability. Microb Biotechnol 1:320–330. https://doi.org/10.1111/j.1751-7915.2008.00022.x
Malik A (2004) Metal bioremediation through growing cells. Environ Int 30:261–278. https://doi.org/10.1016/j.envint.2003.08.001
Malik LA, Bashir A, Qureashi A, Pandith AH (2019) Detection and removal of heavy metal ions: a review. Environ Chem Lett 17:1495–1521. https://doi.org/10.1007/s10311-019-00891-z
Mauro JM, Pazirandeh M (2000) Construction and expression of functional multi-domain polypeptides in Escherichia coli: expression of the Neurospora crassa metallothionein gene. Lett Appl Microbiol 30:161–166. https://doi.org/10.1046/j.1472-765x.2000.00697.x
McNerney MP, Michel CL, Kishore K, Standeven J, Styczynski MP (2019) Dynamic and tunable metabolite control for robust minimal-equipment assessment of serum zinc. Nat Commun 10:5514. https://doi.org/10.1038/s41467-019-13454-1
Mendoza-Cozatl DG, Jobe TO, Hauser F, Schroeder JI (2011) Long-distance transport, vacuolar sequestration, tolerance, and transcriptional responses induced by cadmium and arsenic. Curr Opin Plant Biol 14:554–562. https://doi.org/10.1016/j.pbi.2011.07.004
Niu ZX, Sun LN, Sun TH (2011) The bioadsorption of cadmium and lead by bacteria in root exudates culture. Soil Sediment Contam 20:877–891. https://doi.org/10.1080/15320383.2011.620042
Pang Y, Ren X, Li J, Liang F, Rao X, Gao Y, Wu W, Li D, Wang J, Zhao J, Hong X, Jiang F, Wang W, Zhou H, Lyu J, Tan G (2019) Development of a sensitive Escherichia coli bioreporter without antibiotic markers for detecting bioavailable copper in water environments. Front Microbiol 10:3031. https://doi.org/10.3389/fmicb.2019.03031
Pardo R, Herguedas M, Barrado E, Vega M (2003) Biosorption of cadmium, copper, lead and zinc by inactive biomass of Pseudomonas Putida. Anal Bioanal Chem 376:26–32. https://doi.org/10.1007/s00216-003-1843-z
Patel J, Zhang Q, McKay RM, Vincent R, Xu Z (2010) Genetic engineering of Caulobacter crescentus for removal of cadmium from water. Appl Biochem Biotechnol 160:232–243. https://doi.org/10.1007/s12010-009-8540-0
Peng SH, Wang R, Yang LZ, He L, He X, Liu X (2018a) Biosorption of copper, zinc, cadmium and chromium ions from aqueous solution by natural foxtail millet shell. Ecotoxicol Environ Saf 165:61–69. https://doi.org/10.1016/j.ecoenv.2018.08.084
Peng W, Li X, Song J, Jiang W, Liu Y, Fan W (2018b) Bioremediation of cadmium- and zinc-contaminated soil using Rhodobacter sphaeroides. Chemosphere 197:33–41. https://doi.org/10.1016/j.chemosphere.2018.01.017
Plegaria JS, Dzul SP, Zuiderweg ER, Stemmler TL, Pecoraro VL (2015) Apoprotein structure and metal binding characterization of a de Novo designed peptide, alpha3DIV, that sequesters toxic heavy metals. Biochemistry 54:2858–2873. https://doi.org/10.1021/acs.biochem.5b00064
Rahman Z, Singh VP (2020) Bioremediation of toxic heavy metals (THMs) contaminated sites: concepts, applications and challenges. Environ Sci Pollut Res Int 27:27563–27581. https://doi.org/10.1007/s11356-020-08903-0
Riether KB, Dollard MA, Billard P (2001) Assessment of heavy metal bioavailability using Escherichia coli zntAp::lux and copAp::lux-based biosensors. Appl Microbiol Biotechnol 57:712–716. https://doi.org/10.1007/s00253-001-0852-0
Rittle J, Field MJ, Green MT, Tezcan FA (2019) An efficient, step-economical strategy for the design of functional metalloproteins. Nat Chem 11:434–441. https://doi.org/10.1038/s41557-019-0218-9
Saffar B, Yakhchali B, Arbabi M (2007) Development of a bacterial surface display of hexahistidine peptide using CS3 pili for bioaccumulation of heavy metals. Curr Microbiol 55:273–277. https://doi.org/10.1007/s00284-005-0511-2
Samuelson P, Wernerus H, Svedberg M, Stahl S (2000) Staphylococcal surface display of metal-binding polyhistidyl peptides. Appl Environ Microbiol 66:1243–1248. https://doi.org/10.1128/AEM.66.3.1243-1248.2000
Shahid M, Dumat C, Khalid S, Niazi NK, Antunes PMC (2017) Cadmium bioavailability, uptake, toxicity and detoxification in soil-plant system. Rev Environ Contam Toxicol 241:73–137. https://doi.org/10.1007/398_2016_8
Sharma P, Pandey AK, Kim S-H, Singh SP, Chaturvedi P, Varjani S (2021) Critical review on microbial community during in-situ bioremediation of heavy metals from industrial wastewater. Environ Technol Innovat 24:101826. https://doi.org/10.1016/j.eti.2021.101826
Shi Z, Zhang Z, Yuan M, Wang S, Yang M, Yao Q, Ba W, Zhao J, **e B (2020) Characterization of a high cadmium accumulating soil bacterium, Cupriavidus sp. WS2. Chemosphere 247:125834. https://doi.org/10.1016/j.chemosphere.2020.125834
Singh A, Kumar V (2021) Recent advances in synthetic biology-enabled and natural whole-cell optical biosensing of heavy metals. Anal Bioanal Chem 413:73–82. https://doi.org/10.1007/s00216-020-02953-6
Sinha S, Mukherjee SK (2009) Pseudomonas aeruginosa KUCD1, a possible candidate for cadmium bioremediation. Braz J Microbiol 40:655–662. https://doi.org/10.1590/S1517-838220090003000030
Sousa C, Cebolla A, de Lorenzo V (1996) Enhanced metalloadsorption of bacterial cells displaying poly-His peptides. Nat Biotechnol 14:1017–1020. https://doi.org/10.1038/nbt0896-1017
Sousa C, Kotrba P, Ruml T, Cebolla A, De Lorenzo V (1998) Metalloadsorption by Escherichia coli cells displaying yeast and mammalian metallothioneins anchored to the outer membrane protein LamB. J Bacteriol 180:2280–2284. https://doi.org/10.1128/JB.180.9.2280-2284.1998
Suhani I, Sahab S, Srivastava V, Singh RP (2021) Impact of cadmium pollution on food safety and human health. Curr Opin Toxicol 27:1–7. https://doi.org/10.1016/j.cotox.2021.04.004
Tafakori V, Ahmadian G, Amoozegar MA (2012) Surface display of bacterial metallothioneins and a chitin binding domain on Escherichia coli increase cadmium adsorption and cell immobilization. Appl Biochem Biotechnol 167:462–473. https://doi.org/10.1007/s12010-012-9684-x
Tao HC, Peng ZW, Li PS, Yu TA, Su J (2013) Optimizing cadmium and mercury specificity of CadR-based E. coli biosensors by redesign of CadR. Biotechnol Lett 35:1253–1258. https://doi.org/10.1007/s10529-013-1216-4
USEPA (2009) National primary drinking water regulations. Washington, USA
USEPA (2016) National recommended water quality criteria. Washington, USA
Valls M, Atrian S, de Lorenzo V, Fernandez LA (2000a) Engineering a mouse metallothionein on the cell surface of Ralstonia eutropha CH34 for immobilization of heavy metals in soil. Nat Biotechnol 18:661–665. https://doi.org/10.1038/76516
Valls M, de Lorenzo V, Gonzalez-Duarte R, Atrian S (2000b) Engineering outer-membrane proteins in Pseudomonas putida for enhanced heavy-metal bioadsorption. J Inorg Biochem 79:219–223. https://doi.org/10.1016/s0162-0134(99)00170-1
VanZile ML, Chen X, Giedroc DP (2002) Allosteric negative regulation of smt O/P binding of the zinc sensor, SmtB, by metal ions: a coupled equilibrium analysis. Biochemistry 41:9776–9786. https://doi.org/10.1021/bi020178t
Vijayaraghavan K, Yun YS (2008) Bacterial biosorbents and biosorption. Biotechnol Adv 26:266–291. https://doi.org/10.1016/j.biotechadv.2008.02.002
Waldron KJ, Rutherford JC, Ford D, Robinson NJ (2009) Metalloproteins and metal sensing. Nature 460:823–830. https://doi.org/10.1038/nature08300
Wan X, Volpetti F, Petrova E, French C, Maerkl SJ, Wang B (2019) Cascaded amplifying circuits enable ultrasensitive cellular sensors for toxic metals. Nat Chem Biol 15:540–548. https://doi.org/10.1038/s41589-019-0244-3
Wang B, Barahona M, Buck M (2013) A modular cell-based biosensor using engineered genetic logic circuits to detect and integrate multiple environmental signals. Biosens Bioelectron 40:368–376. https://doi.org/10.1016/j.bios.2012.08.011
Wang B, Buck M (2012) Customizing cell signaling using engineered genetic logic circuits. Trends Microbiol 20:376–384. https://doi.org/10.1016/j.tim.2012.05.001
Wang D, Zheng Y, Fan X, Xu L, Pang T, Liu T, Liang L, Huang S, **ao Q (2020) Visual detection of Hg2+ by manipulation of pyocyanin biosynthesis through the Hg2+-dependent transcriptional activator MerR in microbial cells. J Biosci Bioeng 129:223–228. https://doi.org/10.1016/j.jbiosc.2019.08.005
Wang Y, Kendall J, Cavet JS, Giedroc DP (2010) Elucidation of the functional metal binding profile of a Cd(II)/Pb(II) sensor CmtR(Sc) from Streptomyces coelicolor. Biochemistry 49:6617–6626. https://doi.org/10.1021/bi100490u
Wang Y, Selvamani V, Yoo I-K, Kim TW, Hong SH (2021) A novel strategy for the microbial removal of heavy metals: cell-surface display of peptides. Biotechnol Bioprocess Eng 26:1–9. https://doi.org/10.1007/s12257-020-0218-z
WHO (2011) Guidelines for drinking-water quality. Geneva, Switzerland
Wu CH, Le D, Mulchandani A, Chen W (2009) Optimization of a whole-cell cadmium sensor with a toggle gene circuit. Biotechnol Prog 25:898–903. https://doi.org/10.1002/btpr.203
Xue Y, Wang Y, Wang S, Yan M, Huang J, Yang X (2020) Label-free and regenerable aptasensor for real-time detection of cadmium(II) by dual polarization interferometry. Anal Chem 92:10007–10015. https://doi.org/10.1021/acs.analchem.0c01710
Yang D, Park SY, Lee SY (2021) Production of rainbow colorants by metabolically engineered Escherichia coli. Adv Sci (weinh) 8:e2100743. https://doi.org/10.1002/advs.202100743
Yang T, Chen M-L, Wang J-H (2015) Genetic and chemical modification of cells for selective separation and analysis of heavy metals of biological or environmental significance. Trends Anal Chem 66:90–102. https://doi.org/10.1016/j.trac.2014.11.016
Yilmaz EI, Ensari NY (2005) Cadmium biosorption by Bacillus circulans strain EB1. World J Microbiol Biotechnol 21:777–779. https://doi.org/10.1007/s11274-004-7258-y
Yin K, Lv M, Wang Q, Wu Y, Liao C, Zhang W, Chen L (2016) Simultaneous bioremediation and biodetection of mercury ion through surface display of carboxylesterase E2 from Pseudomonas aeruginosa PA1. Water Res 103:383–390. https://doi.org/10.1016/j.watres.2016.07.053
Yin K, Wang Q, Lv M, Chen L (2019) Microorganism remediation strategies towards heavy metals. Chem Eng J 360:1553–1563. https://doi.org/10.1016/j.cej.2018.10.226
Yoon Y, Kim S, Chae Y, Kang Y, Lee Y, Jeong SW, An YJ (2016a) Use of tunable whole-cell bioreporters to assess bioavailable cadmium and remediation performance in soils. PLoS One 11:e0154506. https://doi.org/10.1371/journal.pone.0154506
Yoon Y, Kim S, Chae Y, Kim SW, Kang Y, An G, Jeong SW, An YJ (2016b) Simultaneous detection of bioavailable arsenic and cadmium in contaminated soils using dual-sensing bioreporters. Appl Microbiol Biotechnol 100:3713–3722. https://doi.org/10.1007/s00253-016-7338-6
Yu F, Cangelosi VM, Zastrow ML, Tegoni M, Plegaria JS, Tebo AG, Mocny CS, Ruckthong L, Qayyum H, Pecoraro VL (2014) Protein design: toward functional metalloenzymes. Chem Rev 114:3495–3578. https://doi.org/10.1021/cr400458x
Yu Y, Shi K, Li X, Luo X, Wang M, Li L, Wang G, Li M (2021) Reducing cadmium in rice using metallothionein surface-engineered bacteria WH16-1-MT. Environ Res 203:111801. https://doi.org/10.1016/j.envres.2021.111801
Zhang NX, Guo Y, Li H, Yang XQ, Gao CX, Hui CY (2021) Versatile artificial mer operons in Escherichia coli towards whole cell biosensing and adsorption of mercury. PLoS One 16:e0252190. https://doi.org/10.1371/journal.pone.0252190
Zhu N, Zhang B, Yu Q (2020) Genetic engineering-facilitated coassembly of synthetic bacterial cells and magnetic nanoparticles for efficient heavy metal removal. ACS Appl Mater Interfaces 12:22948–22957. https://doi.org/10.1021/acsami.0c04512
Ziagova M, Dimitriadis G, Aslanidou D, Papaioannou X, Litopoulou Tzannetaki E, Liakopoulou-Kyriakides M (2007) Comparative study of Cd(II) and Cr(VI) biosorption on Staphylococcus xylosus and Pseudomonas sp. in single and binary mixtures. Bioresour Technol 98:2859–2865. https://doi.org/10.1016/j.biortech.2006.09.043
Zouboulis AI, Loukidou MX, Matis KA (2004) Biosorption of toxic metals from aqueous solutions by bacteria strains isolated from metal-polluted soils. Process Biochem 39:909–916. https://doi.org/10.1016/S0032-9592(03)00200-0
Funding
This work was supported by the National Natural Science Foundation of China (82073517), the Natural Science Foundation of Guangdong Province (2019A1515011989, 2021A1515012472), the Science and Technology Program of Shenzhen (JCYJ20180306170237563, JCYJ20190808175205480, and KCXFZ20201221173602007), Shenzhen Key Medical Discipline Construction Fund (SZXK068), and Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties (SZGSP015).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare the they have no conflict of interest to declare.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Hui, Cy., Guo, Y., Liu, L. et al. Recent advances in bacterial biosensing and bioremediation of cadmium pollution: a mini-review. World J Microbiol Biotechnol 38, 9 (2022). https://doi.org/10.1007/s11274-021-03198-w
Received:
Accepted:
Published:
DOI: https://doi.org/10.1007/s11274-021-03198-w