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Incidence and factors associated with deep vein thrombosis among hospitalized adult patients at Hawassa university comprehensive specialized hospital Hawassa city, Sidama, Ethiopia: retrospective cohort study

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Abstract

Purpose

Deep vein thrombosis is a public health problem with substantial morbidity and mortality globally. In Ethiopia, death due to complications of DVT is very significant however its incidence, risk factors, and preventive methods are not well studied. To assess the incidence and factors associated with deep vein thrombosis among hospitalized adult patients at Hawassa University Comprehensive Specialized Hospital, Hawassa, Ethiopia.

Method

Intuitional-based retrospective study design was employed in July1-August 30, 2022 in 660 randomly selected patients’ record cards. The patients' record cards were reviewed from 2012 to 2014 at Hawassa University Compressive Specialized Hospital. The data entry and analysis were done by using Epi Info and SPSS version 24. After adjusting covariates at a 95% confidence interval, an independent variable with a P value < 0.05 was declared significantly associated with deep vein thrombosis. An odds ratio was calculated to measure the strength of the relationship independent variable and deep vein thrombosis.

Results

The overall incidence of DVT was 10.6% [95% CI: 8.5%, 13.1%]. After adjusting for covariates, orthopedic trauma; AOR = 2.6 (95% CI (1.2–5.4), corona virus; AOR = 2.5 (95%CI (1.07–5.1), and hospital stay > 15 days; AOR = 2.2 (95% CI (1.25–3.94) were significantly associated with deep vein thrombosis.

Conclusion

DVT incidence is high among hospitalized patients. An orthopedic trauma, a recent infection of the coronavirus, and a hospital stay above 15 days were a risk to acquire deep vein thrombosis. Early identification and detection of patients at high risk of develo** DVT and provision of prophylaxis are recommended.

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Data availability

All the data reported in the manuscript are publicly available upon acceptance of the manuscript.

Abbreviations

BMI :

Body mass index

CA :

Cancer

CHF :

Congestive heart failure

CKD :

Chronic kidney disease

CLD :

Chronic liver disease

DM :

Diabetes mellitus

DVT :

Deep vein thrombosis

HTN :

Hypertension

HUCSH :

Hawassa, University, comprehensive specialized Hospital.

ICU :

Intensive care unit

INR :

International normalized ratio

PE :

Pulmonary embolism

PICC :

Peripherally inserted catheter care

PT :

Prothrombin time

PTS :

Pulmonary thrombi syndrome

PTT :

Partial thromboplastin time

SPSS :

Statistical package for social science

UFH :

Unfractionated heparin

VT :

Venous thrombosis

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Acknowledgements

Authors would like to acknowledge Sidama Regional Health Bureau for their facilitation for data collection process at Hawassa University Comprehensive Specialized Hospital. We would like to extend our appreciation to Hawassa University Comprehensive Specialized Hospital for their kind support in data collection process. We would like to acknowledge data collectors and supervisors who took part in data collection.

Funding

Authors cover the research work by themselves.

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Authors and Affiliations

  1. School of Public Health, Hawassa University, Hawassa, Ethiopia

    Tsegaye Alemu

  2. Hawassa University Comprehensive Specialized Hospital, Hawassa, Ethiopia

    Aklilu Adule

  3. Department of Pharmacy, School of Medicine, Komar University of Science and Technology, Qularaisi, Sulaimaniyah, KRI, Iraq

    Mende Mensa Sorato

  4. Department of Human Anatomy, College of Medicine and Health Science, Hawassa University, Hawassa, Ethiopia

    Asfaw Borsamo

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  1. Tsegaye Alemu
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Contributions

TA, AA, MM, and AB contributed in conception, study design, data collection at Hospital, data analysis and interpretation. TA and MM edited the manuscript, critically reviewed the manuscript. All authors read and approved the manuscript before submission.

Corresponding author

Correspondence to Mende Mensa Sorato.

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Conflict of interest

The author declare that they have no conflict of interest.

Ethical approval

Ethical clearance was obtained from the research and ethical committee of the department of public health, Pharma College, Hawassa, Campus. Acceptance letter from respective health institution was collected before reviewing the registration books. Data were kept secured so that only investigators and data collectors were accessing the place. After extraction, the records were returned to the registry and placed on their shelves without any affection of routine service. And the information letter was taken from the adult medical ward, ICU, and orthopedic ward.

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Alemu, T., Adule, A., Sorato, M.M. et al. Incidence and factors associated with deep vein thrombosis among hospitalized adult patients at Hawassa university comprehensive specialized hospital Hawassa city, Sidama, Ethiopia: retrospective cohort study. J Thromb Thrombolysis 57, 164–174 (2024). https://doi.org/10.1007/s11239-023-02889-5

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