It is demonstrated that the antibiotic therapy is the main therapy of infectious complications after surgical operations whose efficiency multiply increases due to the application of the mechanical suture in the form of Π-shaped titanium alloy staples with medicinal coating comprising various groups of medical preparations. The medical preparation immobilized by the corresponding method possesses programmed kinetics of release and provides the optimal concentration during the required time in the region of its application. The laser ablation method of forming the surface of Π-shaped titanium oxide staples is considered that allows a pit with a preset profile to be formed and its adhesive properties to be improved to obtain the required kinetics of medical preparation release.
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Translated from Izvestiya Vysshikh Uchebnykh Zavedenii, Fizika, No. 11, pp. 76–80, November, 2013.
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Ermakov, V.V., Leitman, A.G., Reimer, I.V. et al. Formation of the Titanium Oxide Surface by the Laser Ablation Method. Russ Phys J 56, 1292–1296 (2014). https://doi.org/10.1007/s11182-014-0175-0
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DOI: https://doi.org/10.1007/s11182-014-0175-0