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Structural features and differences for moieties of 4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidines and 4,7-dihydro-1,2,4-triazolo[4,3-a]pyrimidines according to X-ray diffraction data

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Abstract

The structures of substituted 6-benzyloxycarbonyl-7-(het)aryl-5-methyl-4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidines and isomeric 6-benzyloxycarbonyl-7-aryl-5-methyl-4,7-dihydro-1,2,4-triazolo[4,3-a]pyrimidines were studied by X-ray diffraction. Distinctive structural features of these compounds were revealed.

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Funding

The study was performed within the framework of the of the state assignments Nos FUWM-2024-0009 and FUWM-2024-0011 using the equipment of the Joint Use Center “Spectroscopy and Analysis of Organic Compounds” (CJU “SAOC”) of the I. Ya. Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences.

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Authors and Affiliations

  1. I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22/20 ul. S. Kovalevskoi, 620108, Yekaterinburg, Russian Federation

    P. A. Slepukhin, E. S. Filatova, O. V. Fedorova, G. L. Rusinov & V. N. Charushin

Authors
  1. P. A. Slepukhin
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  2. E. S. Filatova
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  3. O. V. Fedorova
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  4. G. L. Rusinov
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  5. V. N. Charushin
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Corresponding author

Correspondence to E. S. Filatova.

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No human or animal subjects were used in this research.

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The authors declare no competing interests.

Additional information

Based on the materials of the VII International Conference “Modern Synthetic Methodologies for Creating Drugs and Functional Materials” (MOSM 2023) dedicated to the 125th birth anniversary of Academician I. Ya. Postovsky (September 10–16, 2023, Yekaterinburg—Perm, Russia).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, Vol. 72, No. 12, pp. 2953–2964, December, 2023.

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Slepukhin, P.A., Filatova, E.S., Fedorova, O.V. et al. Structural features and differences for moieties of 4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidines and 4,7-dihydro-1,2,4-triazolo[4,3-a]pyrimidines according to X-ray diffraction data. Russ Chem Bull 72, 2953–2964 (2023). https://doi.org/10.1007/s11172-023-4106-5

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