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Novel ether-functional spiro-tetronic acid derivatives: molecule design, convenient synthesis and biological evaluation

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Abstract

A novel series of ether functionalization of spiro-tetronic acid derivatives have been designed and conveniently synthesized via three steps, including esterification, one-pot heterocyclization, and etherification reactions. The target molecules have been identified on the basis of analytical spectra data. All newly synthesized compounds have been screened for their potential insecticidal activity against Heliothis armigera and Plutella xylostella compared with spirodiclofen by standard method.

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Acknowledgment

This work was financially supported by the Projects in the Youth Science Foundation of Hubei Academy of Agricultural Sciences (2011NKYJJ19) and the Special Fund for Agro-Scientific Research in the Public Interest (200903052).

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Authors and Affiliations

  1. Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Sciences, Wuhan, 430064, People’s Republic of China

    Shaoyong Ke, Zhigang Zhang, Ya-Ni Zhang, Liqiao Shi, Ronghua Zhou, Aibing Jiang, Ying Liang & Ziwen Yang

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  1. Shaoyong Ke
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  2. Zhigang Zhang
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  3. Ya-Ni Zhang
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  4. Liqiao Shi
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  8. Ziwen Yang
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Correspondence to Shaoyong Ke.

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Shaoyong Ke and Zhigang Zhang contributed equally to this work.

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Ke, S., Zhang, Z., Zhang, YN. et al. Novel ether-functional spiro-tetronic acid derivatives: molecule design, convenient synthesis and biological evaluation. Res Chem Intermed 38, 1827–1837 (2012). https://doi.org/10.1007/s11164-012-0506-0

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