Log in

Human Papillomavirus Vaccination Initiation and Completion among Youth Experiencing Homelessness in Seven U.S. Cities

  • Published:
Prevention Science Aims and scope Submit manuscript

Abstract

Little is known about human papillomavirus (HPV) vaccination uptake among youth experiencing homelessness (YEH), who may be at higher risk for HPV than their housed counterparts. We examined the prevalence and associations of HPV vaccination initiation and completion among YEH. Guided by the Behavioral Model for Vulnerable Populations, we analyzed cross-sectional data collected from YEH (N = 1074; ages 18–26) in seven U.S. cities to assess HPV vaccination prevalence and to identify predisposing, enabling, and need factors associated with HPV vaccination status. Due to timing differences in the release of HPV vaccine recommendations, we conducted separate logistic regression analyses for men (n = 673) and women (n = 401). Approximately 19% of men and 37% of women had initiated and completed HPV vaccination. Several factors among men (i.e., older age, Latinx ethnicity, San Jose or St. Louis residence compared with New York City, never having had sex, and not previously being tested for STIs) and women (i.e., lower education level, San Jose or Houston residence compared with New York City, and never having had sex) were associated with lower odds of HPV vaccination initiation, completion, or both. Gay men had higher odds of initiating and completing the vaccination series than their heterosexual counterparts. Our findings reveal that HPV vaccination uptake is low among YEH and that there are vaccination disparities among subgroups of YEH. HPV vaccination strategies and resources that are easy-to-understand, facilitate point-of-care services, and address societal and system-level vaccination barriers encountered by YEH are needed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Agénor, M., Peitzmeier, S. M., Gordon, A. R., Charlton, B. M., Haneuse, S., Potter, J., et al. (2016). Sexual orientation identity disparities in human papillomavirus vaccination initiation and completion among young adult US women and men. Cancer Causes & Control, 27, 1187–1196.

    Google Scholar 

  • Andersen, R. M. (1995). Revisiting the behavioral model and access to medical care: Does it matter? Journal of Health and Social Behavior, 36, 1–10.

    CAS  PubMed  Google Scholar 

  • Barman-Adhikari, A., & Rice, E. (2011). Sexual health information seeking online among runaway and homeless youth. Journal of the Society for Social Work and Research, 2, 89–103.

    Google Scholar 

  • Beharry, M., Harpin, S. B., AlMakadma, A., Ammerman, S., Eisenstein, E., Warf, C., et al. (2018). The healthcare needs and rights of youth experiencing homelessness society for adolescent health and medicine. Journal of Adolescent Health, 63, 372–375.

    Google Scholar 

  • Caccamo, A., Kachur, R., & Williams, S. P. (2017). Narrative review: Sexually transmitted diseases and homeless youth—What do we know about sexually transmitted disease prevalence and risk? Sexually Transmitted Diseases, 44, 466–476.

    PubMed  PubMed Central  Google Scholar 

  • Cahill, S., Singal, R., Grasso, C., King, D., Mayer, K., Baker, K., et al. (2014). Do ask, do tell: High levels of acceptability by patients of routine collection of sexual orientation and gender identity data in four diverse American community health centers. PLoS One, 9, e107104.

    PubMed  PubMed Central  Google Scholar 

  • Cartmell, K. B., Young-Pierce, J., McGue, S., Alberg, A. J., Luque, J. S., Zubizarreta, M., et al. (2018). Barriers, facilitators, and potential strategies for increasing HPV vaccination: A statewide assessment to inform action. Papillomavirus Research, 5, 21–31.

    PubMed  Google Scholar 

  • Centers for Disease Control and Prevention. (2011). Recommendations on the use of quadrivalent human papillomavirus vaccine in males--Advisory Committee on Immunization Practices (ACIP), 2011. MMWR. Morbidity and Mortality Weekly Report, 60, 1705.

  • Centers for Disease Control and Prevention. (2018). Vaccination coverage among adults in the United States, National Health Interview Survey. 2016. Retrieved from https://www.cdc.gov/vaccines/imz-managers/coverage/adultvaxview/pubs-resources/NHIS-2016.html. Accessed 25 Sept 2018.

  • Centers for Disease Control and Prevention. (n.d.-a). General Best Practice Guidelines for Immunization: Timing and Spacing of Immunobiologics. Retrieved from https://www.cdc.gov/vaccines/hcp/acip-recs/general-recs/timing.html#unknown. Accessed 26 Feb 2020.

  • Centers for Disease Control and Prevention. (n.d.-b). Vaccines for Children Program. Retrieved from https://www.cdc.gov/vaccines/programs/vfc/index.html. Accessed 7 Nov 19.

  • Centers for Disease Control and Prevention. (n.d.-c). Vaccine Records. Retrieved from https://www.cdc.gov/vaccines/parents/records/find-records.html. Accessed 26 Feb 2019.

  • Child Welfare Information Gateway. (2015). Health-care coverage for youth in foster care—and after. Retrieved from https://www.childwelfare.gov/pubPDFs/health_care_foster.pdf. Accessed 20 June 2019.

  • Cooper, D. L., Hernandez, N. D., Rollins, L., Akintobi, T. H., & McAllister, C. (2017). HPV vaccine awareness and the association of trust in cancer information from physicians among males. Vaccine, 35, 2661–2667.

    PubMed  PubMed Central  Google Scholar 

  • Dawson, A., & Jackson, D. (2013). The primary health care service experiences and needs of homeless youth: A narrative synthesis of current evidence. Contemporary Nurse, 44, 62–75.

    PubMed  Google Scholar 

  • Diviani, N., van den Putte, B., Giani, S., & van Weert, J. C. (2015). Low health literacy and evaluation of online health information: A systematic review of the literature. Journal of Medical Internet Research, 17, e112.

    PubMed  PubMed Central  Google Scholar 

  • Doroshenko, A., Hatchette, J., Halperin, S. A., MacDonald, N. E., & Graham, J. E. (2012). Challenges to immunization: The experiences of homeless youth. BMC Public Health, 12, 338.

    PubMed  PubMed Central  Google Scholar 

  • Drolet, M., Bénard, É., Pérez, N., Brisson, M., Ali, H., Boily, M.-C., et al. (2019). Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: Updated systematic review and meta-analysis. The Lancet., 394, 497–509.

    Google Scholar 

  • Ensign, J. (2001). The health of shelter-based foster youth. Public Health Nursing, 18, 19–23.

    CAS  PubMed  Google Scholar 

  • Ensign, J., & Bell, M. (2004). Illness experiences of homeless youth. Qualitative Health Research, 14, 1239–1254.

    PubMed  Google Scholar 

  • Fontenot, H. B., John, T. L.-S., Vetters, R., Funk, D., Grasso, C., & Mayer, K. H. (2016). The association of health seeking behaviors with human papillomavirus vaccination status among high-risk urban youth. Sexually Transmitted Diseases, 43, 771–777.

    PubMed  Google Scholar 

  • Gelberg, L., Andersen, R. M., & Leake, B. D. (2000). The behavioral model for vulnerable populations: Application to medical care use and outcomes for homeless people. Health Services Research, 34, 1273.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Gilkey, M. B., & McRee, A.-L. (2016). Provider communication about HPV vaccination: A systematic review. Human Vaccines & Immunotherapeutics, 12, 1454–1468.

    Google Scholar 

  • Grimaldi-Bensouda, L., Aubrun, E., Leighton, P., Benichou, J., Rossignol, M., Abenhaim, L., et al. (2013). Agreement between patients’ self-report and medical records for vaccination: The PGRx database. Pharmacoepidemiology and Drug Safety, 22, 278–285.

    PubMed  Google Scholar 

  • Gwadz, M. V., Gostnell, K., Smolenski, C., Willis, B., Nish, D., Nolan, T. C., et al. (2009). The initiation of homeless youth into the street economy. Journal of Adolescence, 32, 357–377.

    PubMed  Google Scholar 

  • Hall, K. S., Moreau, C., & Trussell, J. (2012). Determinants of and disparities in reproductive health service use among adolescent and young adult women in the United States, 2002–2008. American Journal of Public Health, 102, 359–367.

    PubMed  PubMed Central  Google Scholar 

  • Healthy People 2020. (2014). Office of Disease Prevention and Health Promotion. Retrievd from https://www.healthypeople.gov/2020/topics-objectives/topic/immunization-and-infectious-diseases/objectives. Accessed 15 Oct 2018.

  • Helitzer, D., Hollis, C., Cotner, J., & Oestreicher, N. (2009). Health literacy demands of written health information materials: An assessment of cervical cancer prevention materials. Cancer Control, 16, 70–78.

    PubMed  Google Scholar 

  • Henderson, C. E., Rich, J. D., & Lally, M. A. (2010). HPV vaccination practices among juvenile justice facilities in the United States. Journal of Adolescent Health, 46, 495–498.

    PubMed  Google Scholar 

  • Henrikson, N. B., Tuzzio, L., Gilkey, M. B., & McRee, A.-L. (2016). “You’re never really off time”: Healthcare providers’ interpretations of optimal timing for HPV vaccination. Preventive Medicine Reports, 4, 94–97.

    PubMed  PubMed Central  Google Scholar 

  • Henry, K. A., Swiecki-Sikora, A. L., Stroup, A. M., Warner, E. L., & Kepka, D. (2018). Area-based socioeconomic factors and human papillomavirus (HPV) vaccination among teen boys in the United States. BMC Public Health, 18, 19.

    Google Scholar 

  • Hirth, J., Kuo, Y.-F., Laz, T. H., Starkey, J. M., Rupp, R. E., Rahman, M., et al. (2016). Concordance of adolescent human papillomavirus vaccination parental report with provider report in the National Immunization Survey-Teen (2008–2013). Vaccine, 34, 4415–4421.

    PubMed  PubMed Central  Google Scholar 

  • Hosmer Jr., D. W., Lemeshow, S., & Sturdivant, R. X. (2013). Applied logistic regression. Hoboken: Wiley.

    Google Scholar 

  • Hudson, A. L., Nyamathi, A., Greengold, B., Slagle, A., Koniak-Griffin, D., Khalilifard, F., et al. (2010). Health-seeking challenges among homeless youth. Nursing Research, 59, 212.

    PubMed  PubMed Central  Google Scholar 

  • IBM Corporation. (2016). SPSS for windows, version 24. IBM Corp Armonk (NY).

  • Jemal, A., Simard, E. P., Dorell, C., Noone, A.-M., Markowitz, L. E., Kohler, B., et al. (2013). Annual report to the nation on the status of cancer, 1975–2009, featuring the burden and trends in human papillomavirus (HPV)–associated cancers and HPV vaccination coverage levels. JNCI: Journal of the National Cancer Institute, 105, 175–201.

    PubMed  PubMed Central  Google Scholar 

  • Jeudin, P., Liveright, E., Del Carmen, M. G., & Perkins, R. B. (2014). Race, ethnicity, and income factors impacting human papillomavirus vaccination rates. Clinical Therapeutics, 36, 24–37.

    PubMed  Google Scholar 

  • Kann, L., McManus, T., Harris, W. A., Shanklin, S. L., Flint, K. H., Hawkins, J., & et al. (2016). Youth risk behavior surveillance .

  • Kester, L. M., Zimet, G. D., Fortenberry, J. D., Kahn, J. A., & Shew, M. L. (2013). A national study of HPV vaccination of adolescent girls: Rates, predictors, and reasons for non-vaccination. Maternal and Child Health Journal, 17, 879–885.

    PubMed  PubMed Central  Google Scholar 

  • Kontos, E. Z., Emmons, K. M., Puleo, E., & Viswanath, K. (2012). Contribution of communication inequalities to disparities in human papillomavirus vaccine awareness and knowledge. American Journal of Public Health, 102, 1911–1920.

    PubMed  PubMed Central  Google Scholar 

  • Markowitz, L. E., Dunne, E., Saraiya, M., Lawson, H., Chesson, H., & Unger, E. (2007). Quadrivalent human papillomavirus vaccine. MMWR. Morbidity and Mortality Weekly Report, 56, 1–24.

    Google Scholar 

  • Meites, E. (2016). Use of a 2-dose schedule for human papillomavirus vaccination—Updated recommendations of the Advisory Committee on Immunization Practices. MMWR. Morbidity and Mortality Weekly Report, 65, 1405–1408.

    PubMed  Google Scholar 

  • Meites, E., Szilagyi, P. G., Chesson, H. W., Unger, E. R., Romero, J. R., & Markowitz, L. E. (2019). Human papillomavirus vaccination for adults: Updated recommendations of the Advisory Committee on Immunization Practices. American Journal of Transplantation, 19, 3202–3206.

    Google Scholar 

  • Milburn, N. G., Rosenthal, D., Rotheram-Borus, M. J., Mallett, S., Batterham, P., Rice, E., et al. (2007). Newly homeless youth typically return home. Journal of Adolescent Health, 40, 574–576.

    PubMed  Google Scholar 

  • Milburn, N. G., Rice, E., Rotheram-Borus, M. J., Mallett, S., Rosenthal, D., Batterham, P., et al. (2009). Adolescents exiting homelessness over two years: The risk amplification and abatement model. Journal of Research on Adolescence, 19, 762–785.

    PubMed  PubMed Central  Google Scholar 

  • Moran, M. B., Frank, L. B., Chatterjee, J. S., Murphy, S. T., & Baezconde-Garbanati, L. (2016). A pilot test of the acceptability and efficacy of narrative and non-narrative health education materials in a low health literacy population. Journal of Communication in Healthcare, 9, 40–48.

    PubMed  PubMed Central  Google Scholar 

  • Narendorf, S. C., Santa Maria, D., & Cooper, J. (2015). Youth count 2.0! Full report of findings. Houston, TX.

  • Pergamit, M. R., Ernst, M., & Hall, C. (2010). Runaway youth’s knowledge and access of services. National Runaway Switchboard, Chicago IL. Retrieved from http://www.1800runaway.org/media/documents/NORC_Final_Report_4_22_10.pdf. Accessed 12 April 2018.

  • Rolnick, S., Parker, E., Nordin, J., Hedblom, B., Wei, F., Kerby, T., et al. (2013). Self-report compared to electronic medical record across eight adult vaccines: Do results vary by demographic factors? Vaccine, 31, 3928–3935.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Santa Maria, D., Flash, C. A., Narendorf, S., Barman-Adhikari, A., Petering, R., Hsu, H. T., et al. (2019). Knowledge and attitudes about pre-exposure prophylaxis among young adults experiencing homelessness in seven US cities. Journal of Adolescent Health, 64, 574–580.

    PubMed  Google Scholar 

  • Satterwhite, C. L., Torrone, E., Meites, E., Dunne, E. F., Mahajan, R., Ocfemia, M. C. B., et al. (2013). Sexually transmitted infections among US women and men: Prevalence and incidence estimates, 2008. Sexually Transmitted Diseases, 40, 187–193.

    PubMed  Google Scholar 

  • Schmidt, S., & Parsons, H. M. (2014). Vaccination interest and trends in human papillomavirus vaccine uptake in young adult women aged 18 to 26 years in the United States: An analysis using the 2008–2012 National Health Interview Survey. American Journal of Public Health, 104, 946–953.

    PubMed  PubMed Central  Google Scholar 

  • Schwarz, K., Garrett, B., Lamoreux, J., Bowser, Y., Weinbaum, C., & Alter, M. (2005). Hepatitis B vaccination rate of homeless children in Baltimore. Journal of Pediatric Gastroenterology and Nutrition, 41, 225–229.

    CAS  PubMed  Google Scholar 

  • Simons, H. R., Unger, Z. D., Lopez, P. M., & Kohn, J. E. (2015). Predictors of human papillomavirus vaccine completion among female and male vaccine initiators in family planning centers. American Journal of Public Health, 105, 2541–2548.

    PubMed  PubMed Central  Google Scholar 

  • Stoltzfus, J. C. (2011). Logistic regression: A brief primer. Academic Emergency Medicine, 18, 1099–1104.

    PubMed  Google Scholar 

  • The HPV Vaccine: Access and Use in the U.S. (2018). Henry J Kaiser Family Foundation. https://www.kff.org/womens-health-policy/fact-sheet/the-hpv-vaccine-access-and-use-in-the-u-s/. Accessed 14 Jun 2019.

  • Van Den Berg, J. J., Larson, H. E., Zimet, G. D., & Lally, M. A. (2014). Bundling human papillomavirus vaccination and rapid human immunodeficiency virus testing for young gay and bisexual men. LGBT Health, 1, 233–237.

    PubMed  Google Scholar 

  • Walker, T. Y., Elam-Evans, L. D., Singleton, J. A., Yankey, D., Markowitz, L. E., Fredua, B., et al. (2017). National, regional, state, and selected local area vaccination coverage among adolescents aged 13–17 years—United States, 2016. MMWR. Morbidity and Mortality Weekly Report, 66, 874.

    PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgments

We would like to thank the youth who participated in the HYRRS study, and the REALYST.org study team and community partners. We would also like to thank Lionel Santibáñez for his editorial assistance.

Funding

This work was partially supported by the Greater Houston Community Foundation Funders Together to End Homelessness; and the Arizona State University Institute for Social Science Research.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kathryn R. Gallardo.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committees and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gallardo, K.R., Santa Maria, D., Narendorf, S. et al. Human Papillomavirus Vaccination Initiation and Completion among Youth Experiencing Homelessness in Seven U.S. Cities. Prev Sci 21, 937–948 (2020). https://doi.org/10.1007/s11121-020-01131-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11121-020-01131-5

Keywords

Navigation