The infusion from the aerial part of common lady’s mantle Alchemilla vulgaris L. injected preliminarily for 5 d exhibited neuroprotective properties by normalizing conditioned reflexes and orientational-exploratory behavior indicators of animals after hypoxic exposure. Infusion at a dose of 5 mL/kg was the most active. A. vulgaris infusion at a dose of 5 mL/kg with activation of lipid peroxidation after hypoxic action normalized the content of thiobarbiturate-reactive products in brain homogenate and reduced the concentration of antiradical antioxidants in the lipid extract.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 53, No. 11, pp. 37 – 41, November, 2019.
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Shilova, I.V., Suslov, N.I., Samylina, I.A. et al. Neuroprotective Properties of Common Lady’s Mantle Infusion. Pharm Chem J 53, 1059–1062 (2020). https://doi.org/10.1007/s11094-020-02122-0
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DOI: https://doi.org/10.1007/s11094-020-02122-0