SpringerLink
Log in

Implications and interchangeability of meningioma biomarkers for clinical trials and clinical practice

  • Correspondence
  • Published:
Journal of Neuro-Oncology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price includes VAT (Germany)

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Data availability

No datasets were generated or analysed during the current study.

References

  1. Clark VE, Erson-Omay EZ, Serin A et al (2013) Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO. Science 339:1077–1080. https://doi.org/10.1126/science.1233009

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Chen WC, Choudhury A, Youngblood MW et al (2023) Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses. Nat Med 1–1. https://doi.org/10.1038/s41591-023-02586-z

  3. Sahm F, Schrimpf D, Stichel D et al (2017) DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis. Lancet Oncol. https://doi.org/10.1016/s1470-2045(17)30155-9

    Article  PubMed  Google Scholar 

  4. Choudhury A, Magill ST, Eaton CD et al (2022) Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat Genet 54:649–659. https://doi.org/10.1038/s41588-022-01061-8

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Nassiri F, Liu J, Patil V et al (2021) A clinically applicable integrative molecular classification of meningiomas. Nature 597:119–125. https://doi.org/10.1038/s41586-021-03850-3

    Article  CAS  PubMed  Google Scholar 

  6. Maas SLN, Stichel D, Hielscher T et al (2021) Integrated Molecular-Morphologic Meningioma classification: a Multicenter Retrospective Analysis, retrospectively and prospectively validated. J Clin Oncol JCO 2100784. https://doi.org/10.1200/jco.21.00784

  7. Choudhury A, Chen WC, Lucas C-HG et al (2022) Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features. https://doi.org/10.1093/neuonc/noac224. Neuro-oncology

Download references

Acknowledgements

The authors thanks Tony Wang and Jiayi Huang for inspiring the analyses in Fig. 1 and Kanish Mirchia for consultation.

Funding

NIH grants R01 CA262311 and P50 CA097257, and the Trenchard Family Charitable Fund, to DRR.

Author information

Authors and Affiliations

  1. Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA

    David R. Raleigh & William C. Chen

  2. Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA

    David R. Raleigh

  3. Department of Pathology, University of California San Francisco, San Francisco, CA, USA

    David R. Raleigh

  4. Department of Radiation Oncology, Northwestern University, Chicago, IL, USA

    Vinai Gondi

  5. Radiation Oncology, Utah Cancer Specialists, Salt Lake City, UT, USA

    Leland Rogers

  6. Miami Cancer Institute, Baptist Health, Miami, FL, USA

    Minesh Mehta

  7. Departments of Radiation Oncology, Neurological Surgery, and Pathology, University of California San Francisco, Helen Diller Family Cancer Research Building 1450 3rd Street, HD481, 94158, San Francisco, CA, USA

    David R. Raleigh

Authors
  1. David R. Raleigh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. William C. Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Vinai Gondi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Leland Rogers
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Minesh Mehta
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

D.R.R. and W.C.C. performed analyses. D.R.R. wrote the manuscript with input from W.C.C., V.G., L.R., and M.M.

Corresponding author

Correspondence to David R. Raleigh.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

*Correspondence:

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Raleigh, D.R., Chen, W.C., Gondi, V. et al. Implications and interchangeability of meningioma biomarkers for clinical trials and clinical practice. J Neurooncol (2024). https://doi.org/10.1007/s11060-024-04700-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11060-024-04700-8

Search

Navigation