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Fluorescent Switch-on Detection of Cadmium(II) Using Salicylaldehyde-Decorated Gold Nanoclusters

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Abstract

In this study, salicylaldehyde (SA) conjugated gold nanoclusters were synthesized, characterized, and applied for the fluorescent turn-on sensing of Cd2+. The trypsin-stabilized fluorescent gold nanocluster (Tryp-AuNCs, λem = 680 nm) was modified with SA to form the spherical-shaped SA_Tryp-AuNCs. After modification, the red-emitting Tryp-AuNCs turned to green-emitting SA_Tryp-AuNCs because of the formation of imine linkage between the -CHO group of SA with the -NH2 group of functionalized trypsin. The modified SA_Tryp-AuNCs selectively interacted with Cd2+ and exhibited a fluorescence enhancement at 660 nm. The Cd2+ detection with SA_Tryp-AuNCs is simple and rapid with an estimated nanomolar detection limit of 98.1 nM. The practical utility of SA_Tryp-AuNCs was validated by quantifying Cd2+ in real environmental water samples.

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All data generated during this study are included in this published article.

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Authors and Affiliations

  1. Department of Chemistry, Sardar Vallabhbhai National Institute Technology, 395007, Surat, Gujarat, India

    Aditi Tripathi, Vinita Bhardwaj & Suban K Sahoo

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  1. Aditi Tripathi
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  2. Vinita Bhardwaj
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  3. Suban K Sahoo
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Contributions

All authors contributed to the study. The Investigation, Validation, Formal analysis, Data curation, Writing-original draft were performed by Aditi Tripathi. Vinita Bhardwaj helps in Formal analysis and Writing-original draft. The Conceptualization, Resources, Supervision, and Writing-review & editing were performed by Suban K Sahoo.

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Correspondence to Suban K Sahoo.

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Tripathi, A., Bhardwaj, V. & Sahoo, S.K. Fluorescent Switch-on Detection of Cadmium(II) Using Salicylaldehyde-Decorated Gold Nanoclusters. J Fluoresc (2023). https://doi.org/10.1007/s10895-023-03497-5

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