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Long-term outcome of ventricular tachycardia ablation in patients who did not undergo programmed electrical stimulation after ablation

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Abstract

Background

Ventricular arrhythmia inducibility is one of the ideal endpoints of ventricular tachycardia (VT) ablation. However, it may be challenging to implement programmed electrical stimulation (PES) at the end of the procedure under several circumstances. The long-term outcome of patients who did not undergo PES after VT ablation remains largely unknown.

Purpose

To investigate the details and long-term outcome of VT ablation in patients who did not undergo PES at the end of the ablation procedure.

Methods

Among 183 VT ablation procedures in patients with structural heart disease who underwent VT ablation using an irrigated catheter, we enrolled those who did not undergo PES after VT ablation. VT ablation strategy involved targeting clinical VT plus pacemap-guided substrate ablation if inducible. When VT was not inducible, substrate-based ablation was performed. The primary endpoint was VT recurrence.

Results

In 58 procedures, post-ablation VT inducibility was not assessed. The causes were non-inducibility of sustained VT before ablation (27/58, 46.6%), long procedure time (27.6%, mean 392 min), complications (10.3%), intolerant hemodynamic state (10.3%), and inaccessible or unsafe target (6.9%). With regard to the primary endpoint, 23 recurrences (39.7%) were observed during a mean follow-up period of 2.5 years. Patients with non-inducibility before ablation showed less VT recurrences (4/27, 14.8%) during follow-up than patients with other causes of untested PES after ablation (19/31, 61.2%) (Log-rank < 0.001).

Conclusions

VT recurrence was not observed in approximately 60% of the patients who did not undergo PES at the end of the ablation procedure. PES after VT ablation may be not needed among patients with pre-ablation non-inducibility.

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Authors and Affiliations

  1. Department of Cardiology, Tokyo Metropolitan Hiroo Hospital, 2 – 34 – 10 Ebisu, Shibuya-ku, Tokyo, Japan

    Takeshi Kitamura, Seiji Fukamizu, Tomoyuki Arai, Kohei Kawajiri, Sho Tanabe, Sayuri Tokioka, Dai Inagaki & Rintaro Hojo

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  1. Takeshi Kitamura
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  2. Seiji Fukamizu
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  3. Tomoyuki Arai
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  4. Kohei Kawajiri
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Correspondence to Takeshi Kitamura.

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Kitamura, T., Fukamizu, S., Arai, T. et al. Long-term outcome of ventricular tachycardia ablation in patients who did not undergo programmed electrical stimulation after ablation. J Interv Card Electrophysiol 66, 215–220 (2023). https://doi.org/10.1007/s10840-021-01037-4

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