Cyclocondensation reactions of methyl trifluoropyruvate N-(pyrimidin-2-yl)imines with N-substituted ureas, N-benzylbenzamidine, 2-aminothiazoline, methyl 3-aminocrotonate, and 6-aminouracils leading to imidazolidine-2,4-diones, 3,5-dihydroimidazol-4-ones, 2,3-dihydroimidazo[2,1-d][1,3]thiazol-5(6H)-one, 4,5-dihydro-1H-pyrroles, and 5,7-dihydro-1H-pyrrolo[2,3-d]pyrimidine-2,4,6-triones have been studied.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 468-473, March, 2013.
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Sokolov, V.B., Aksinenko, A.Y., Epishina, T.A. et al. Methyl trifluoropyruvate N-(pyrimidin-2-yl)imines in cyclocondensation reactions with 1,3-binucleophilic reagents. Chem Heterocycl Comp 49, 435–439 (2013). https://doi.org/10.1007/s10593-013-1265-6
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DOI: https://doi.org/10.1007/s10593-013-1265-6
Keywords
- 2-aminothiazoline
- 6-aminouracils
- N-benzylbenzamidine
- 3,5-dihydroimidazol-4-ones
- 2,3-dihydroimidazo[2,1-d][1,3]thiazol-5(6H)-one
- 4,5-dihydro-1H-pyrroles
- 5,7-dihydro-1H-pyrrolo[2,3-d]- pyrimidine-2,4,6-triones
- imidazolidine-2,4-dione
- methyl 3-aminocrotonate
- methyl trifluoropyruvate N-(pyrimidin-2-yl)imines
- N-substituted ureas
- cyclocondensation