Abstract
Palladium acetate has been shown to be a highly active catalyst for Heck reactions of aryl chlorides even in the absence of organic ligands. Bromobenzene can efficiently be coupled in presence of negligible traces of Pd, resulting in the highest TON (4.7 × 107) and TOF (1.2 × 107 h−1) values that have ever been reported for this system up to now.
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Acknowledgments
Manfred Barth and his co-workers (Mikroanalytisches Labor, TU München) are gratefully acknowledged for the performance of Pd trace analysis
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Kleist, W., Pröckl, S.S. & Köhler, K. Heck Reactions of Aryl Chlorides Catalyzed by Ligand Free Palladium Salts. Catal Lett 125, 197–200 (2008). https://doi.org/10.1007/s10562-008-9533-2
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DOI: https://doi.org/10.1007/s10562-008-9533-2