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Letter to editor: C‑reactive protein levels, the prognostic nutritional index, and the lactate dehydrogenase‑to‑lymphocyte ratio are important prognostic factors in primary central nervous system lymphoma: a single‑center study of 223 patients

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Abstract

This critique evaluates a letter to the editor discussing prognostic factors in primary central nervous system lymphoma (PCNSL), focusing on C-reactive protein (CRP) levels, prognostic nutritional index (PNI), and lactate dehydrogenase (LDH)-to-lymphocyte ratio. While the letter provides valuable insights, limitations including reliance on a single-center dataset, lack of consideration for potential confounders, insufficient contextualization within existing literature, and limited discussion of clinical implications are identified. Addressing these limitations is crucial for enhancing the relevance and applicability of the findings in PCNSL management.

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References

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The authors received no extramural funding for the study.

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The conceptualization was done by ZUNM. The literature and drafting of the manuscript were conducted by ZUNM and AH. The editing and supervision were performed by ZUNM and AH. The authors have read and agreed to the final version of the manuscript.

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Correspondence to Abdul Haseeb.

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The authors declare no potential conflicts of interest concerning the research, authorship, and/or publication of this article.

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Un Nisa Mughal, Z., Haseeb, A. Letter to editor: C‑reactive protein levels, the prognostic nutritional index, and the lactate dehydrogenase‑to‑lymphocyte ratio are important prognostic factors in primary central nervous system lymphoma: a single‑center study of 223 patients. Neurosurg Rev 47, 146 (2024). https://doi.org/10.1007/s10143-024-02387-z

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  • DOI: https://doi.org/10.1007/s10143-024-02387-z

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