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Experimental study on the safety of photobiologic regulation therapy in the treatment of some non-epidermal tumors

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Abstract

This study investigates the impact of Photobiomodulation (PBM) at different wavelengths on non-superficial cancer cells. Utilizing three laser protocols (650 nm, 810 nm, and 915 nm), the research explores cytotoxic effects, ROS generation, and cell migration. Results reveal varied responses across cell lines, with 810 nm PBM inducing significant ROS levels and inhibiting PAN-1 cell migration. The study suggests potential therapeutic applications for PBM in non-superficial cancers, emphasizing the need for further exploration in clinical settings.

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Authors and Affiliations

  1. Central Laboratory, Bei**g Luhe Hospital, Capital Medical University, Bei**g, China

    Fang Nie, Hao Sun & Yan Zhang

  2. Department of General Surgery, Bei**g Luhe Hospital, Capital Medical University, Bei**g, China

    Yu Ji, Zeqian Lee & Wei Han

  3. Department of Neurosurgery, Wayne State University School of Medicine, Detroit, USA

    YuChuan Ding

Authors
  1. Fang Nie
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  2. Yu Ji
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  3. Hao Sun
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  4. Zeqian Lee
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  5. Yan Zhang
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  6. Wei Han
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  7. YuChuan Ding
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Corresponding authors

Correspondence to Wei Han or YuChuan Ding.

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Nie, F., Ji, Y., Sun, H. et al. Experimental study on the safety of photobiologic regulation therapy in the treatment of some non-epidermal tumors. Lasers Med Sci 39, 180 (2024). https://doi.org/10.1007/s10103-024-04121-z

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