Abstract
Objectives
The purpose of this study was to investigate the heritability of dental cephalometric variables by analyzing vertical linear measurements and angular measurements of the upper incisor, canine, and first molar.
Materials and methods
Among the 553 Korean patients who participated in twin studies conducted at Samsung Medical Center, 150 patients had their lateral cephalometric radiograph data included in this study. The group was comprised of 36 monozygotic (MZ) twins (males, 16 pairs; females, 20 pairs), 13 dizygotic (DZ) twins (males, 7 pairs; females, 6 pairs), and 26 same-sex sibling pairs (males, 11 pairs; females, 15 pairs). All patients were over 20 years old with a mean age of 39.75 years. Lateral cephalometric diagrams and linear measurements (6 vertical factors, 6 horizontal factors) were taken. Three axial planes were measured for each tooth; intraclass correlation coefficients (ICCs) were obtained for each group and heritability was calculated using Falconer’s method.
Results
ICCs of vertical linear measurements (average 0.837, P < 0.01) and the tooth axis of the central incisor and canine (average 0.679, P < 0.001) were higher in the MZ group compared to the DZ and sibling groups; thus, these variables showed high heritability.
Conclusions
Orthodontic treatment aiming to alter the tooth axis of the maxillary central incisor or canine or other vertical factors with greater heritability can be difficult, requiring strategic treatment planning to achieve desired treatment outcome and stability.
Clinical relevance
The active early treatment to gain tooth eruption space can lead to normal tooth position.
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Data availability
The data supporting the study can be obtained directly from the authors.
This study was approved by the ins.titutional review board (IRB) of the Ajou University Hospital (IRB No.: AJIRB-MED-MDB-18–295). Subjects read and signed their informed consents.
Abbreviations
- MZ:
-
Monozygotic twins
- DZ:
-
Dizygotic (DZ) twins
- ICCs:
-
Intraclass correlation coefficients
- MMB:
-
Maxillo-mandibular bisector
- PTV:
-
Pterygoid vertical
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The individual roles of each author were as follows:
• Kang Geon Woo: collection of data, analysis of data, interpretation of data, construction of manuscript
• Young Ho Kim: review of literature, collection of data, analysis of data, interpretation of data, construction of manuscript
• Christine Hong: conception and design of the article, construction of manuscript
• Sunghae Woo: fabricating figures and tables.
• Joohon Sung: conception and design of the article
• Yun-Mi Song: conception and design of the article
• Jeong Won Shin: conception and design of the article
• Hwa Sung Chae: conception and design of the article, analysis of data, interpretation of data, construction of manuscript
• All the authors read and approved the final manuscript.
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Kang, G.W., Kim, Y.H., Hong, C. et al. Heritability of maxillary dental cephalometric variables among monozygotic twins, dizygotic twins and their siblings. Clin Oral Invest 26, 6275–6281 (2022). https://doi.org/10.1007/s00784-022-04579-7
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DOI: https://doi.org/10.1007/s00784-022-04579-7