Zusammenfassung
Dilatative Erkrankungen der Aorta descendens und des Aortenbogens wurden früher meist offen-chirurgisch transthorakal, häufig unter Einsatz eines Linksherzbypasses, rekonstruiert. Inzwischen wurden die etablierten chirurgischen Standardverfahren an der thorakalen Aorta durch endoluminale Strategien ergänzt und erweitert. Insbesondere beim kardiopulmonalen Risikopatienten, nach vorausgegangenen kardiochirurgischen Eingriffen sowie beim Notfallpatienten im Stadium der Ruptur mit hämorrhagischem Schock sind die Ergebnisse der offenen Chirurgie noch unbefriedigend und mit einer hohen Morbiditäts- und Mortalitätsrate verbunden. Die präoperative Planung des endovaskulären Eingriffs stellt neue Anforderungen an die Bildgebung. Durch optimierte multiplanare Rekonstruktion können Implantationsstrategie und Therapieerfolg in der Nachsorge langfristig gesichert werden. Die endovaskuläre Behandlung von thorakalen Aortenläsionen geht mit niedriger Krankenhausmortalität und relativ niedriger Morbidität einher. Auch die Rupturrate endovaskulär versorgter Aneurysmen ist im Verlauf sehr niedrig. Problem der neuen Technologie ist die Haltbarkeit der Systeme im Langzeitverlauf. Deswegen ist eine engmaschige, lebenslange, klinische und bildgebende Nachsorge erforderlich, um auftretende Probleme rechtzeitig erkennen und beheben zu können.
Abstract
Experience with endovascular repair of abdominal aortic aneurysms has led to the development of minimally invasive techniques to treat thoracic aortic pathologies. Such inhomogenous diseases challenge surgeons to perform complex surgical repairs in high-risk patients. The minimally invasive nature of thoracic endografting provides an attractive alternative therapy, especially in patients deemed unfit for thoracotomy. A worldwide review of thoracic endografting demonstrates encouraging short and midterm outcomes with significant reductions in morbidity and early mortality and acceptable freedom from aneurysm related death. Close long-term surveillance and serial imaging studies will be crucial to discovering complications unique to thoracic endografting and to detecting device failure prior to the development of devastating clinical sequelae. As this technology matures, endovascular therapy may become the preferred initial therapy for many thoracic aortic lesions. More specific selection of patients may further reduce mortality and morbidity.
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs00772-005-0399-y/MediaObjects/s00772-005-0399-yfhb1.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs00772-005-0399-y/MediaObjects/s00772-005-0399-yfhb2.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs00772-005-0399-y/MediaObjects/s00772-005-0399-yflb3.gif)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs00772-005-0399-y/MediaObjects/s00772-005-0399-yfhb4.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs00772-005-0399-y/MediaObjects/s00772-005-0399-yfhb5.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs00772-005-0399-y/MediaObjects/s00772-005-0399-yfhb6.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs00772-005-0399-y/MediaObjects/s00772-005-0399-yfhb7.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs00772-005-0399-y/MediaObjects/s00772-005-0399-yfhb8.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs00772-005-0399-y/MediaObjects/s00772-005-0399-yfhb9.jpg)
Literatur
Allenberg JR, Schumacher H (2003) Endovaskuläre Rekonstruktion der thorakalen Aorta: eine klinische Standortbestimmung nach 6-jähriger Erfahrung. Gefäßchirurgie [Suppl 1] 8: S75–S84
Borst HG, Jurmann M, Bühner B, Laas J (1994) Risk of replacement of descending aorta with a standardized left heart bypass technique. J Thorac Cardiovasc Surg 107: 126–133
Cardarelli MG, McLaughlin JS, Downing SW, Borwn JM, Attar S, Griffith BP (2002) Management of traumatic aortic rupture: a 30-year experience. Ann Surg 236: 465–470
Chuter TA, Schneider DB, Reilly LM et al. (2003) Modular branched stent graft for endovascular repair of aortic arch aneurysm and dissection. J Vasc Surg 38: 859–863
Clouse WD, Hallett JW, Schaff HV, Gayari MM, Ilstrub DM, Melton LJ (1998) Improved prognosis of thoracic aortic aneurysms. JAMA 280: 1926–1929
Cooley DA, Golino A, Frazier OH (2000) Single-clamp technique for aneurysms of the descending thoracic aorta: report of 132 consecutive cases. Eur J Cardiothorac Surg 18: 162–167
Criado FJ, Clark NS, Barnatan MF (2002) Stent graft repair in the aortic arch and descending thoracic aorta: a 4-year experience. J Vasc Surg 36: 1121–1128
Dake MD, Miller DC, Semba CP, Mitchell RS, Walker PJ, Liddel RP (1994) Transluminal placement of endovascular stent-grafts for the treatment of descending aortic aneurysms. N Engl J Med 331: 1729–1734
Demers Ph, Miller DC, Mitchell RS, Kee ST, Sze D, Razavi MK et al. (2004) Midterm results of endovascular repair of descending thoracic aortic aneurysms with first-generation stent grafts. J Thorac Cardiovasc Surg 127: 664–673
Elefteriades JA (2002) Natural history of thoracic aortic aneurysms: indications for surgery, and surgical versus nonsurgical risks. Ann Thorac Surg 74: S1877–S1880
Ellozy SH, Carroccio A, Minor M et al. (2003) Challenges of endovascular tube graft repair of thoracic aortic aneurysm: midterm follow-up and lessons learned. J Vasc Surg 38: 676–683
Glade GJ, Vahl AC, Wisselink W, Linsen MAM, Balm R (2005) Mid-term survival and costs of treatment of patients with descending thoracic aortic aneurysms; endovascular vs. open repair: a case-control study. Eur J Vasc Endovasc Surg 29: 28–34
Görich J, Asquan Y, Seifarth H, Krämer S, Kapfer X, Orend KH et al. (2002) Initial experience with intentional stent-graft coverage of the subclavian artery during endovascular thoracic aorta repairs. J Endovasc Ther 9: II39–43
Inoue K, Hosokawa H, Iwase T et al. (1999) Aortic arch reconstruction by transluminally placed endovascular branched stent graft. Circulation 100: 316–321
Keogh BE, Kinsman R (1999) National audit cardiac surgical data base report 1998. The Society of Cardiothoracic Surgeons of Great Britain & Ireland, Concord Services, London
Kieffer E, Koskas F, Cluzel Ph et al. (2004) Endoluminal repair of the aortic arch combined with revascularization of supra-aortic arteries. In: Branchereau A, Jacobs M (eds) Hybrid vascular procedures. Blackwell Futura Publishing Company, Malden, MA, pp 75–84
Kouchoukos NT, Dougenis D (1997) Surgery of the thoracic aorta. N Engl J Med 336: 1876–1888
Leurs LJ, Bell R, Degrieck Y et al. (2004) On behalf of the EUROSTAR and the UK Thoracic Endograft Registry collaborators. Endovascular treatment of thoracic aortic diseases: combined experience from the EUROSTAR and United Kingdom Thoracic Endograft registries. J Vasc Surg 40: 670–680
Makaroun MS, Dillavou ED, Kee ST et al. (2005) Endovascular treatment of thoracic aortic aneurysms: results of the phase II multicenter trial of the GORE TAG thoracic endoprothesis. J Vasc Surg 41: 1–9
Melissano G, Civilini E, Bertoglio L, Setacci F, Chiesa R (2005) Endovascular treatment of aortic arch aneurysms. Eur J Vasc Endovasc Surg 29: 131–138
Orend KH, Scharrer-Pamler R, Kapfer X, Kotsis T, Görich J, Sunder-Plassmann L (2003) Endovascular treatment in diseases of the descending thoracic aorta: 6-year results of a single center. J Vasc Surg 37: 91–99
Schumacher H, Bardenheuer HJ, Hansmann J, Böckler D, Allenberg JR (2003) Endovascular aortic arch reconstruction with supra-aortic transposition for plaque rupture and dissection: early experience in 8 high-risk patients. J Endovasc Ther 10: 1066–1074
Schumacher H, Bardenheuer HJ, Richter GM, Allenberg JR (2003) Endovaskulärer Bogenersatz: Alternative für den Risikopatienten. Chir Allgemeine 4: 164–170
Schumacher H, Böckler D, Allenberg JR (2004) Chirurgische Therapie thorakaler Aortenläsionen: Aneurysma, Dissektion und traumatische Ruptur. Chirurg 75: 937–958
Schumacher H, Böckler D, Tengg-Kobligk H, Lopez-Benitez R, Ockert S, Allenberg JR (2005) Symptomatische Plaqueruptur und penetrierendes Ulkus im thorako-abdominellen Aortenabschnitt. Wen operieren und mit welcher Technik? Gefäßchirurgie 10: 38–50
Svensson LG, Crawford ES, Hess KR, Coselli JS, Safi HJ (1993) Variables predictive of outcome in 832 patients undergoing repairs of the descending thoracic aorta. Chest 104: 1248–1253
Taylor PR, Gaines PA, McGuinness et al. (2001) Thoracic aortic stent grafts — early experience from two centres using commercially available devices. Eur J Vasc Endovasc Surg 22: 70–76
Temudom T, D’Ayala M, Marin ML et al. (2000) Endovascular grafts in the treatment of thoracic aortic aneurysms and pseudoaneurysms. Ann Vasc Surg 14: 230–238
Thompson CS, Gaxotte VD, Rodriguez JA et al. (2002) Endoluminal stent grafting of the thoracic aorta: initial experience with the Gore Excluder. J Vasc Surg 35: 1163–1170
Interessenkonflikt:
Keine Angaben
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Schumacher, H., Böckler, D. & Allenberg, JR. Endovaskuläre Therapie thorakaler Aortenaneurysmen. Gefässchirurgie 10, 203–220 (2005). https://doi.org/10.1007/s00772-005-0399-y
Issue Date:
DOI: https://doi.org/10.1007/s00772-005-0399-y
Schlüsselwörter
- Thorakales Aortenaneurysma
- Thorakal, endovaskuläre Chirurgie
- Stentprothese
- Implantationstechnik
- Kardiopulmonaler Risikopatient