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Getah virus epizootic among wild boars in Japan around 2012

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Abstract

In 2014, an outbreak of Getah virus (GETV) infection occurred in Japan in a horse population that was inoculated with a vaccine against GETV. In this study, we investigated the seroprevalence of GETV infection among wild boars in Japan. Interestingly, the highest rate of anti-GETV-positive wild boars was observed in 2013, which gradually decreased during 2014–2016. The results suggested that GETV spread among wild boars around 2012, resulting in the 2014 outbreak.

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References

  1. Griffin DE (2013) Alphaviruses. In: Knipe DM, Howley PM (eds) Fields virology, 6th edn. Lippincott Williams and Wilkins, Philadelphia, pp 651–686

    Google Scholar 

  2. Berge TO (1975) International catalogue of Arboviruses: including certain other viruses of vertebrates, 2nd edn, US Department of Health, Education, and Welfare, pp 278–279

  3. Fukunaga Y, Kumanomido T, Kamada M (2000) Getah virus as an equine pathogen. Vet Clin N Am Equine Pract 16:605–617

    Article  CAS  Google Scholar 

  4. Brown CM, Timoney PJ (1998) Getah virus infection of Indian horses. Trop Anim Health Prod 30:241–252

    Article  PubMed  CAS  Google Scholar 

  5. Yago K, Hagiwara S, Kawamura H, Narita M (1987) A fatal case in newborn piglets with Getah virus infection: isolation of the virus. Nihon Juigaku Zasshi 49:989–994

    Article  PubMed  CAS  Google Scholar 

  6. Izumida A, Takuma H, Inagaki S, Kubota M, Hirahara T, Kodama K, Sasaki N (1988) Experimental infection of Getah virus in swine. Nihon Juigaku Zasshi 50:679–684

    Article  PubMed  CAS  Google Scholar 

  7. Scherner WF, Funkenbusch M, Buescher EL, Izumi T (1962) Sagiyama virus, a new group A arthropod-borne virus from Japan. I. Isolation, immunologic classification, and ecologic observations. Am J Trop Med Hyg 11:255–268

    Article  Google Scholar 

  8. Sanderson CJ (1969) A serologic survey of Queensland cattle for evidence of arbovirus infection. Am J Trop Med Hyg 18:433–439

    Article  PubMed  CAS  Google Scholar 

  9. Li XD, Qiu FX, Yang H, Rao YN, Calisher CH (1992) Isolation of Getah virus from mosquitos collected on Hainan Island, China, and results of a serosurvey. Southeast Asian J Trop Med Public Health 23:730–734

    PubMed  CAS  Google Scholar 

  10. Zhai YG, Wang HY, Sun XH, Fu SH, Wang HQ, Attoui H, Tang Q, Liang GD (2008) Complete sequence characterization of isolates of Getah virus (genus Alphavirus, family Togaviridae) from China. J Gen Virol 89:1446–1456

    Article  PubMed  CAS  Google Scholar 

  11. Kamada M, Ando Y, Fukunaga Y, Kumanomido T, Imagawa H, Wada R, Akiyama Y (1980) Equine Getah virus infection: isolation of the virus from racehorses during an enzootic in Japan. Am J Trop Med Hyg 29:984–988

    Article  PubMed  CAS  Google Scholar 

  12. Nemoto M, Bannai H, Tsujimura K, Kobayashi M, Kikuchi T, Yamanaka T, Kondo T (2015) Getah Virus Infection among Racehorses, Japan, 2014. Emerg Infect Dis 21:883–885

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  13. Bannai H, Ochi A, Nemoto M, Tsujimura K, Yamanaka T, Kondo T (2016) A 2015 outbreak of Getah virus infection occurring among Japanese racehorses sequentially to an outbreak in 2014 at the same site. BMC Vet Res 12:98

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  14. Bannai H, Nemoto M, Ochi A, Kikuchi T, Kobayashi M, Tsujimura K, Yamanaka T, Kondo T (2015) Epizootiological investigation of Getah virus infection among racehorses in Japan in 2014. J Clin Microbiol 53:2286–2291

    Article  PubMed  PubMed Central  Google Scholar 

  15. Nemoto M, Bannai H, Tsujimura K, Yamanaka T, Kondo T (2016) Genomic, pathogenic, and antigenic comparisons of Getah virus strains isolated in 1978 and 2014 in Japan. Arch Virol 161:1691–1695

    Article  PubMed  CAS  Google Scholar 

  16. Kobayashi D, Isawa H, Ejiri H, Sasaki T, Sunahara T, Futami K, Tsuda Y, Katayama Y, Mizutani T, Minakawa N, Ohta N, Sawabe K (2016) Complete genome sequencing and phylogenetic analysis of a Getah virus strain (Genus Alphavirus, family Togaviridae) isolated from Culex tritaeniorhynchus mosquitoes in Nagasaki, Japan in 2012. Vector Borne Zoonotic Dis 16:769–776

    Article  PubMed  Google Scholar 

  17. Wekesa SN, Inoshima Y, Murakami K, Sentsui H (2001) Genomic analysis of some Japanese isolates of Getah virus. Vet Microbiol 83:137–146

    Article  PubMed  CAS  Google Scholar 

  18. Tajima S, Kotaki A, Yagasaki K, Taniwaki T, Moi ML, Nakayama E, Saijo M, Kurane I, Takasaki T (2014) Identification and amplification of Japanese encephalitis virus and Getah virus propagated from a single porcine serum sample: a case of coinfection. Arch Virol 159:2969–2975

    Article  PubMed  CAS  Google Scholar 

  19. Ruiz-Fons F (2017) A review of the current status of relevant zoonotic pathogens in wild swine (Sus scrofa) populations: changes modulating the risk of transmission to humans. Transbound Emerg Dis 64:68–88

    Article  PubMed  CAS  Google Scholar 

  20. Kodera Y (2009) Sus scrofa Linnaeus, 1958. In: Ohdachi SD, Ishibashi Y, Iwasa MA, Saitoh T (eds) The wild mammals of Japan. Shoukadoh Book Sellers, Kyoto, pp 304–305

    Google Scholar 

  21. Suzuki J, Nishio Y, Kameo Y, Terada Y, Kuwata R, Shimoda H, Suzuki K, Maeda K (2015) Canine distemper virus infection among wildlife before and after the epidemic. J Vet Med Sci 77:1457–1463

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  22. Kanda Y (2013) Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics. Bone Marrow Transplant 48:452–458

    Article  PubMed  CAS  Google Scholar 

  23. Shimoda H, Ohno Y, Mochizuki M, Iwata H, Okuda M, Maeda K (2010) Dogs as sentinels for human infection with Japanese encephalitis virus. Emerg Infect Dis 16:1137–1139

    Article  PubMed  PubMed Central  Google Scholar 

  24. Bannai H, Nemoto M, Niwa H, Murakami S, Tsujimura K, Yamanaka T, Kondo T (2017) Geospatial and temporal associations of Getah virus circulation among pigs and horses around the perimeter of outbreaks in Japanese racehorses in 2014 and 2015. BMC Vet Res 13:187

    Article  PubMed  PubMed Central  CAS  Google Scholar 

Download references

Funding

This work was funded in part by Grants-in-Aid from the Japanese Ministry of Health, Labour, and Welfare (201622017A), the Japan Society for the Promotion of Science (15H05262), and the Japan Agency for Medical Research and Development (e-ASIA JRP, H28-shinkou-ippan-017).

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Correspondence to Ken Maeda.

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The authors declare no conflict of interest.

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All animal samples used were collected under permission for hunting by the government.

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Handling Editor: Patricia Aguilar.

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Kuwata, R., Shimoda, H., Phichitraslip, T. et al. Getah virus epizootic among wild boars in Japan around 2012. Arch Virol 163, 2817–2821 (2018). https://doi.org/10.1007/s00705-018-3897-4

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  • DOI: https://doi.org/10.1007/s00705-018-3897-4

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