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Pertussis and respiratory syncytial virus infections

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Abstract

During the winter 2005–2006, all infants <4 months of age admitted for bronchiolitis or acute respiratory tract infection in a tertiary care pediatric hospital in Paris were tested for respiratory syncytial virus (RSV) and pertussis with real-time polymerase-chain reaction (RT-PCR). A positive pertussis-PCR was found in 14/90 (16%) infants infected with RSV and in 5/30 negative for RSV. Similar clinical symptoms were found in all RSV-positive infants with or without pertussis co-infection. Most infants (73%) were not vaccinated against pertussis, and the other children had received one or two injections. In conclusion, pertussis-RSV co-infection is common in young infants, and pertussis-PCR should be used, whenever available.

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References

  1. Bonmarin I, Levy-Bruhl D, Baron S, Guiso N, Njankempo E, Caro V (2007) Renacoq. Pertussis surveillance in French hospitals: results from a 10 year period. Euro Surveill 20:12. [Epub ahead of print]

    Google Scholar 

  2. Crowcroft NS, Booy R, Harrison T, Spicer L, Britto J, Mok Q, Heath P, Murdoch I, Zambon M, George R, Miller E (2003) Severe and unrecognised pertussis in UK infants. Arch Dis Child 88:802–806

    Article  PubMed  CAS  Google Scholar 

  3. Floret D (2001) Groupe de pathologie infectieuse pediatrique, Groupe francophone de reanimation et d’urgence pediatrique. Pediatric deaths due to community-acquired bacterial infection. Survey of French pediatric intensive care units. Arch Pediatr 8:705s–711s

    Article  PubMed  Google Scholar 

  4. Forsyth KD, Campins-Marti M, Caro J, Cherry JD, Greenberg D, Guiso N, Heininger U, Schellekens J, Tan T, von König CH, Plotkin S (2004) Global Pertussis Initiative. Clin Infect Dis 39:1802–1809

    Article  PubMed  Google Scholar 

  5. Korppi M, Hiltunen J (2007) Pertussis is common in nonvaccinated infants hospitalized for respiratory syncytial virus infection. Pediatr Infect Dis J 26:316–318

    Article  PubMed  Google Scholar 

  6. Raymond J, Armengaud JB, Cosnes-Lambe C, Chalumeau M, Bosdure E, Reglier-Poupet H, El-Hajje MJ, Iniguez JL, Moulin F, Poyart C, Gendrel D (2007) Pertussis in young infants: apnoea and intra-familial infection. Clin Microbiol Infect 13:172–175

    Article  PubMed  CAS  Google Scholar 

  7. Riffelmann M, Wirsing von König CH, Caro V, Guiso N (2005) Nucleic acid amplification tests for diagnosis of Bordetella pertussis. J Clin Microbiol 43:4925–4929

    Article  PubMed  CAS  Google Scholar 

  8. Shaikh R, Guris D, Strebel PM, Wharton M (1998) Underreporting of pertussis deaths in the United States: need for improved surveillance. Pediatrics 101:323

    Article  PubMed  CAS  Google Scholar 

  9. von König CH, Halperin S, Riffelmann M, Guiso N (2002) Pertussis of adults and infants. Lancet Infect Dis 2:744–750

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Pediatric and Emergency, Université Paris 5, APHP, Hôpital Saint Vincent de Paul-Cochin, Paris, France

    Cécile Cosnes-Lambe, Martin Chalumeau, Charlotte Pons-Catalano, Florence Moulin, Nathalie de Suremain & Dominique Gendrel

  2. Microbiology Unit, Université Paris 5, APHP, Hôpital Saint Vincent de Paul-Cochin, Paris, France

    Josette Raymond, Hélène Reglier-Poupet, Pierre Lebon & Claire Poyart

  3. Hopital Saint Vincent de Paul, 82 Avenue Denfert-Rochereau, 75014, Paris, France

    Dominique Gendrel

Authors
  1. Cécile Cosnes-Lambe
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  2. Josette Raymond
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  3. Martin Chalumeau
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  4. Charlotte Pons-Catalano
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  5. Florence Moulin
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  6. Nathalie de Suremain
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  7. Hélène Reglier-Poupet
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  8. Pierre Lebon
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  9. Claire Poyart
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  10. Dominique Gendrel
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Corresponding author

Correspondence to Dominique Gendrel.

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Cosnes-Lambe, C., Raymond, J., Chalumeau, M. et al. Pertussis and respiratory syncytial virus infections. Eur J Pediatr 167, 1017–1019 (2008). https://doi.org/10.1007/s00431-007-0633-6

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  • DOI: https://doi.org/10.1007/s00431-007-0633-6

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