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Conservative management for pediatric craniocervical Pott’s disease: A case study and literature review

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Abstract

Craniocervical Pott’s disease is rare, particularly in the pediatric population. The importance of motion preservation in this age group renders managing this disease even more challenging. The literature regarding craniocervical Pott’s disease comes from endemic regions. Most authors will agree on early surgical intervention in cases of neurological compromise or severe instability, while patients with minimal symptoms will do well with conservative management. Controversy remains when patients are mildly symptomatic but with imaging findings concerning for significant instability. Here, we present the case of a 15-year-old male presenting with craniocervical tuberculoma with radiographic instability and advanced bony destruction without overt neurological deficits. He was managed with a rigid cervical collar and completed 1 year of anti-tuberculosis therapy. At 1-year follow-up, he had an intact range of motion, was pain-free, and remained neurologically intact. Although this case suggests good outcomes with conservative management are possible, more long-term follow-up is required to assess the need for delayed surgical intervention in this unique population.

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References

  1. Chaudhary K, Pennington Z, Rathod AK, Laheri V, Bapat M, Sciubba DM, Suratwala SJ (2023) Pathogenesis and staging of craniovertebral tuberculosis: radiographic evaluation, classification, and natural history. Global Spine J 13(8):2155–2167. https://doi.org/10.1177/21925682221074671. Epub 2022 Feb 14. PMID: 35164582; PMCID: PMC10538348

    Article  PubMed  Google Scholar 

  2. Desai SS (1994) Early diagnosis of spinal tuberculosis by MRI. J Bone Joint Surg Br 76B:863–869

    Article  Google Scholar 

  3. Edwards RJ, David KM, Crockard HA (2000) Management of tuberculomas of the craniovertebral junction. Br J Neurosurg 14(1):19–22. https://doi.org/10.1080/02688690042852. PMID: 10884879

    Article  CAS  PubMed  Google Scholar 

  4. Fang D, Leong JC, Fang HS (1983) Tuberculosis of the upper cervical spine. J Bone Joint Surg Br 65(1):47–50. https://doi.org/10.1302/0301-620X.65B1.6822601. PMID: 6822601

    Article  CAS  PubMed  Google Scholar 

  5. Gupta SK, Mohindra S, Sharma BS, Gupta R, Chhabra R, Mukherjee KK, Tewari MK, Pathak A, Khandelwal N, Suresh NM, Khosla VK (2006) Tuberculosis of the craniovertebral junction: is surgery necessary? Neurosurgery 58(6):1144–1150. discussion 1144-1150. https://doi.org/10.1227/01.NEU.0000215950.85745.33. PMID: 16723893

    Article  PubMed  Google Scholar 

  6. Kalra SK, Kumar R, Mahapatra AK (2007) Tubercular atlantoaxial dislocation in children: an institutional experience. J Neurosurg Pediatrics 107:111–118

    Article  Google Scholar 

  7. Kanaan IU, Ellis M, Safi T, Kawi MZ, Coates R (1999) Craniocervical junction tuberculosis: a rare but dangerous disease. Surg Neurol 51(1):21–25. discussion 26. https://doi.org/10.1016/s0090-3019(97)00294-2. PMID: 9952119

    Article  CAS  PubMed  Google Scholar 

  8. Krishnan A, Patkar D, Patankar T et al (2001) Craniovertebral junction tuberculosis: a review of 29 cases. J Comp Assist Tomogr 25:171–176

    Article  CAS  Google Scholar 

  9. Tuli SM (1974) Tuberculosis of the craniovertebral region. Clin Orthop Relat Res 104:209–212. https://doi.org/10.1097/00003086-197410000-00023. PMID: 4416753

    Article  Google Scholar 

  10. Lifeso R (1987) Atlanto-axial tuberculosis in adults. J Bone Joint Surg Br 69(2):183–187. https://doi.org/10.1302/0301-620X.69B2.3818746. PMID: 3818746

    Article  CAS  PubMed  Google Scholar 

  11. Lal AP, Rajshekhar V, Chandy MJ (1992) Management strategies in tuberculous atlanto-axial dislocation. J Neurosurg 6:529–535

    Article  CAS  Google Scholar 

  12. Arunkumar MJ, Rajshekhar V (2002) Outcome in neurologically impaired patients with craniovertebral junction tuberculosis: results of combined anteroposterior surgery. J Neurosurg 97(2 Suppl):166–171. https://doi.org/10.3171/spi.2002.97.2.0166. PMID: 12296673

    Article  PubMed  Google Scholar 

  13. Kotil K, Dalbayrak S, Alan S (2004) Craniovertebral junction Pott’s disease. Br J Neurosurg 18(1):49–55. https://doi.org/10.1080/02688690410001660472. PMID: 15040715

    Article  CAS  PubMed  Google Scholar 

  14. Behari S, Nayak SR, Bhargava V, Banerji D, Chhabra DK, Jain VK (2003) Craniocervical tuberculosis: protocol of surgical management. Neurosurgery 52:72–81

    PubMed  Google Scholar 

  15. Sinha S, Singh AK, Gupta V, Singh D, Takayasu M, Yoshida J (2003) Surgical management and outcome of tuberculous atlantoaxial dislocation: a 15-year experience. Neurosurgery 52(2):331–338; discussion 338–339. https://doi.org/10.1227/01.neu.0000043930.28934.fe. PMID: 12535361

  16. Shukla D, Mongia S, Devi BI, Chandramouli BA, Das BS (2005) Management of craniovertebral junction tuberculosis. Surg Neurol 63(2):101–106. discussion 106. https://doi.org/10.1016/j.surneu.2004.03.019. PMID: 15680641

    Article  PubMed  Google Scholar 

  17. Mehrotra A, Das KK, Nair AP, Kumar R, Srivastava AK, Sahu RN, Kumar R (2013) Pediatric cranio-vertebral junction tuberculosis: management and outcome. Childs Nerv Syst 29(5):809–814. https://doi.org/10.1007/s00381-012-1980-9. Epub 2012 Dec 29 PMID: 23274634

    Article  PubMed  Google Scholar 

  18. Chatterjee S, Das A (2015) Craniovertebral tuberculosis in children: experience of 23 cases and proposal for a new classification. Childs Nerv Syst 31(8):1341–1345. https://doi.org/10.1007/s00381-015-2695-5. Epub 2015 Apr 15 PMID: 25874845

    Article  PubMed  Google Scholar 

  19. Arora S, Sabat D, Maini L, Sural S, Kumar V, Gautam VK, Gupta A, Dhal A (2011) The results of nonoperative treatment of craniovertebral junction tuberculosis: a review of twenty-six cases. J Bone Joint Surg Am 93(6):540–547. https://doi.org/10.2106/JBJS.J.00634. PMID: 21411704

    Article  PubMed  Google Scholar 

  20. Chadha M, Agarwal A, Singh AP (2007) Craniovertebral tuberculosis: a retrospective review of 13 cases managed conservatively. Spine (Phila Pa 1976) 32(15):1629–1634. https://doi.org/10.1097/BRS.0b013e318074d41e. PMID: 17621210

    Article  PubMed  Google Scholar 

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ASP wrote the main manuscript and prepared the figures. AT edited the main manuscript and all authors reviewed the final version.

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Correspondence to Anne-Sophie Parent.

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Parent, AS., Tu, A. Conservative management for pediatric craniocervical Pott’s disease: A case study and literature review. Childs Nerv Syst 40, 1867–1871 (2024). https://doi.org/10.1007/s00381-024-06338-3

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