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Hyperplasien der Schilddrüse

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Zusammenfassung

Die häufigsten morphologischen Veränderungen der Schilddrüse in der täglichen Diagnostik betreffen Hyperplasien der Follikelepithelien (Struma). Der folgende Übersichtsartikel beschäftigt sich mit der Ätiologie, Epidemiologie und Klinik der verschiedenen Formen der Struma sowie deren morphologischer Abgrenzung gegenüber dem Adenom der Schilddrüse. Aus der Hyperplasie der kalzitoninproduzierenden C-Zellen in ihrer neoplastischen Form gehen die familiären medullären Schilddrüsenkarzinome hervor. Der 2. Teil dieses Artikels beschäftigt sich mit der Definition der neoplastischen C-Zell-Hyperplasie und ihrer Unterscheidung von der physiologischen C-Zell-Hyperplasie.

Abstract

Hyperplasia of the follicular epithelium (goitre) is the most common morphological change in the thyroid seen by the pathologist. The present paper deals with the aetiology, epidemiology and clinical features of thyroid hyperplasia and its differential diagnosis from thyroid adenoma. Neoplastic hyperplasia of the calcitonin-producing thyroid C cells gives rise to familial medullary carcinoma. The second part of the paper deals with the definition of neoplastic C cell hyperplasia and its discrimination from physiological C cell hyperplasia.

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Authors and Affiliations

  1. Institut für Pathologie, Universitätsklinikum Essen

    S.-Y. Sheu &  K. W. Schmid

  2. Klinik für Nuklearmedizin, Universitätsklinikum Essen

    R. Görges

  3. Institut für Pathologie, Universitätsklinikum Essen, Hufelandstraße 55, 45122 , Essen

    K. W. Schmid

Authors
  1. S.-Y. Sheu
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  2. R. Görges
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  3. K. W. Schmid
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Correspondence to K. W. Schmid.

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Sheu, SY., Görges, R. & Schmid, K.W. Hyperplasien der Schilddrüse. Pathologe 24, 348–356 (2003). https://doi.org/10.1007/s00292-003-0627-8

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  • DOI: https://doi.org/10.1007/s00292-003-0627-8

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