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Understanding the Fermentation Potentiality For Gibberellic Acid (GA3) Production Using Fungi

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Abstract

Gibberellins represent an important group of potent phytohormones, growth-promoting, closely related diterpenoid acids biologically derived from tetracyclic diterpenoid hydrocarbon. Among these, gibberellic acid (GA3) has received the greatest attention. GA3 is a highly valued plant growth regulator which has various applications in agriculture. It is extensively used for beneficial effects including stem elongation, elimination of dormancy, sex expression, seed germination, flowering, and fruit senescence. Along with plants, many microbes are also producing GA3 as their secondary metabolite, and among these, fungi are reported to produce a higher amount of GA3. Fermentation technology based on submerged fermentation and solid-state fermentation for the production of GA3 has been used with its merits and demerits using Fusarium moniliforme fungus in the industry. Several mathematical models and optimization tools were also designed for enhancing the fermentative yield by researchers. The detailed analysis is essential to understand all the fermentation aspects, various unit parameters, process operation approaches, reduction in cost, and assessment of the possible uses of these models in the production of GA3 for higher yield. Recently, exclusive research is executed to lower down the production cost of GA3 approaching various strategies.

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Acknowledgements

Authors are thankful to Department of Microbiology and Biotechnology, School of Sciences, Gujarat University. We acknowledge the Education Department, Government of Gujarat, India, for the providing research fellowship to J.P. and A.P. under the ScHeme Of Develo** High-quality research (SHODH).

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The authors declare that no funds, grants, or other support was received during the preparation of this manuscript.

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Authors and Affiliations

  1. Department of Microbiology and Biotechnology, University of School of Sciences, Gujarat University, Ahmedabad, Gujarat, 380009, India

    Jaimin B. Pandya, Aanal N. Patani, Vikram H. Raval, Kiransinh N. Rajput & Rakeshkumar R. Panchal

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  1. Jaimin B. Pandya
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  2. Aanal N. Patani
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  3. Vikram H. Raval
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  4. Kiransinh N. Rajput
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  5. Rakeshkumar R. Panchal
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Contributions

Jaimin B. Pandya wrote the manuscript; Aanal N. Patani prepared the figures; Vikram H. Raval and Kiransinh N. Rajput suggested the changes whereas Rakeshkumar R. Panchal corrected the manuscript.

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Correspondence to Rakeshkumar R. Panchal.

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Main Conclusion

This study summarized the research on gibberellic acid (GA3) fermentation processes using fungi and recapitulated the optimization tools for higher GA3 production. Chromatographic methods such as HPLC, GC for GA3 analysis are reviewed.

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Pandya, J.B., Patani, A.N., Raval, V.H. et al. Understanding the Fermentation Potentiality For Gibberellic Acid (GA3) Production Using Fungi. Curr Microbiol 80, 385 (2023). https://doi.org/10.1007/s00284-023-03454-2

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