Abstract
Background
Periorbital lipogranuloma following autologous fat injection into the forehead for cosmetic facial augmentation is a recently described adverse outcome. Patients have typically been treated with surgical excision. This study evaluates the clinical characteristics of periorbital lipogranulomas, and the non-surgical treatment outcomes of these patients.
Methods
This is a noncomparative, interventional case series. A retrospective analysis of clinical data and radiographic images was performed of patients with periorbital lipogranuloma following autologous fat injection. Objective treatment outcomes after intralesional triamcinolone injection and/or oral prednisolone were evaluated by measuring the size of the lipogranulomas pre- and post-treatment. Cosmetic outcomes were also assessed by the subjective satisfaction at the last visit.
Results
Twenty-seven patients were identified with periorbital lipogranuloma following facial autologous fat injection. All patients were female, the mean age was 40 ± 10 years, and 19 patients received cryopreserved fat. Twenty-one patients underwent non-surgical corticosteroid treatment. ‘Resolution’ was achieved in 15 patients (71 %), and ‘Partial Resolution’ was achieved in 5 patients (24 %). One patient (5 %) who took oral prednisone alone showed ‘No Response’. Cosmetic outcomes were classified as ‘Very Satisfied’ in 16 patients (76 %), ‘Satisfied’ in 4 patients (19 %), and ‘Dissatisfied’ in 1 patient (5 %) after corticosteroid treatment.
Conclusion
Periorbital lipogranuloma following autologous fat injection may be diagnosed by history, physical exam, and orbital imaging. Non-surgical corticosteroid treatments showed a good response with few adverse effects and should be considered as a first line of treatment of periorbital granulomas prior to conducting surgical excision.
Level of Evidence IV
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Seo, J.W., Sa, HS. Periorbital Lipogranuloma Following Facial Autologous Fat Injections: Non-surgical Treatment. Aesth Plast Surg 39, 946–952 (2015). https://doi.org/10.1007/s00266-015-0554-0
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DOI: https://doi.org/10.1007/s00266-015-0554-0