Log in

The accuracy of 64-slice MDCT for determining the perforation site of the gastrointestinal tract: ROC analysis

  • Published:
Abdominal Imaging Aims and scope Submit manuscript

Abstract

Purpose

This study was performed to evaluate the diagnostic performance of 64-slice multidetector-row computed tomography (MDCT) for preoperatively detecting the perforation site in patients with gastrointestinal (GI) tract perforations.

Materials and methods

A total of 49 patients with pathologically proven GI tract perforations, who had undergone MDCT were included in this study. The contrast-enhanced axial images (3 mm thick) and multiplanar reformation (MPR) images (3 mm thick) were generated for all the patients. Two radiologists independently reviewed the two sets of MDCT images (axial set: the axial images alone, and combined set: the axial and MPR images) for the detection of the perforation site. The perforation site was considered to be positive according to the direct and indirect findings. The diagnostic accuracy was assessed with a receiver operating characteristic (ROC) analysis. Weighted kappa statistics were used to evaluate the interobserver agreement.

Results

The corresponding values in respect of the first and the second observers for the areas under the ROC curve were 0.984 and 0.966 for the axial set; and 0.998 and 0.973 for the combined set. The differences were not statistically significant between the two data sets for each observer (P > 0.05). Both the observers detected the perforation site in 43 (87.8%) and 40 (81.6%) patients on the axial set, and in 46 (93.9%) and 41 (83.7%) patients on the combined set, respectively. The kappa values between the two observers showed excellent agreement with the two data sets.

Conclusion

64-slice MDCT showed a consistently excellent diagnostic performance for preoperatively determining the perforation site in patients with GI tract perforations, irrespective of the availability of the MPR images.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Furukawa A, Sakoda M, Yamasaki M, et al. (2005) Gastrointestinal tract perforation: CT diagnosis of presence, site, and cause. Abdom Imaging 30:524–534

    Article  PubMed  CAS  Google Scholar 

  2. Kim SH, Shin SS, Jeong YY, et al. (2009) Gastrointestinal tract perforation: MDCT findings according to the perforation sites. Korean J Radiol 10:63–70

    Article  PubMed  Google Scholar 

  3. Cho HS, Yoon SE, Park SH, et al. (2009) Distinction between upper and lower gastrointestinal perforation: usefulness of the periportal free air sign on computed tomography. Eur J Radiol 69:108–113

    Article  PubMed  Google Scholar 

  4. Ghekiere O, Lesnik A, Hoa D, et al. (2007) Value of computed tomography in the diagnosis of the cause of nontraumatic gastrointestinal tract perforation. J Comput Assist Tomogr 31:169–176

    Article  PubMed  Google Scholar 

  5. Hainaux B, Agneessens E, Bertinotti R, et al. (2006) Accuracy of MDCT in predicting site of gastrointestinal tract perforation. AJR Am J Roentgenol 187:1179–1183

    Article  PubMed  Google Scholar 

  6. Kim HC, Shin HC, Park SJ, et al. (2004) Traumatic bowel perforation: analysis of CT findings according to the perforation site and the elapsed time since accident. Clin Imaging 28:334–339

    Article  PubMed  Google Scholar 

  7. Yeung KW, Chang MS, Hsiao CP, Huang JF (2004) CT evaluation of gastrointestinal tract perforation. Clin Imaging 28:329–333

    Article  PubMed  Google Scholar 

  8. Mangini M, Carrafiello G, Lagana D, et al. (2008) Non-traumatic acute bowel disease: differential diagnosis with 64-row MDCT. Emerg Radiol 15:171–178

    Article  PubMed  Google Scholar 

  9. Aschoff AJ (2006) MDCT of the abdomen. Eur Radiol 16(Suppl 7):M54–M57

    PubMed  Google Scholar 

  10. Paulson EK, Jaffe TA, Thomas J, Harris JP, Nelson RC (2004) MDCT of patients with acute abdominal pain: a new perspective using coronal reformations from submillimeter isotropic voxels. AJR Am J Roentgenol 183:899–906

    PubMed  Google Scholar 

  11. Oguro S, Funabiki T, Hosoda K, et al. (2010) 64-slice multidetector computed tomography evaluation of gastrointestinal tract perforation site: detectability of direct findings in upper and lower GI tract. Eur Radiol 20:1396–1403

    Article  PubMed  Google Scholar 

  12. Imuta M, Awai K, Nakayama Y, et al. (2007) Multidetector CT findings suggesting a perforation site in the gastrointestinal tract: analysis in surgically confirmed 155 patients. Radiat Med 25:113–118

    Article  PubMed  Google Scholar 

  13. Ghekiere O, Lesnik A, Millet I, et al. (2007) Direct visualization of perforation sites in patients with a non-traumatic free pneumoperitoneum: added diagnostic value of thin transverse slices and coronal and sagittal reformations for multi-detector CT. Eur Radiol 17:2302–2309

    Article  PubMed  Google Scholar 

  14. Miki T, Ogata S, Uto M, et al. (2004) Multidetector-row CT findings of colonic perforation: direct visualization of ruptured colonic wall. Abdom Imaging 29:658–662

    Article  PubMed  CAS  Google Scholar 

  15. De Long ER, De Long DM, Clarke-Pearson DL (1988) Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44:837–845

    Article  Google Scholar 

  16. Siu WT, Chau CH, Law BK, et al. (2004) Routine use of laparoscopic repair for perforated peptic ulcer. Br J Surg 91:481–484

    Article  PubMed  CAS  Google Scholar 

  17. Bertleff MJ, Halm JA, Bemelman WA, et al. (2009) Randomized clinical trial of laparoscopic versus open repair of the perforated peptic ulcer: the LAMA Trial. World J Surg 33:1368–1373

    Article  PubMed  Google Scholar 

  18. Brofman N, Atri M, Hanson JM, et al. (2006) Evaluation of bowel and mesenteric blunt trauma with multidetector CT. Radiographics 26:1119–1131

    Article  PubMed  Google Scholar 

  19. Iezzi R, Cotroneo AR, Filippone A, et al. (2007) MDCT angiography in abdominal aortic aneurysm treated with endovascular repair: diagnostic impact of slice thickness on detection of endoleaks. AJR Am J Roentgenol 189:1414–1420

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sang Soo Shin.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kim, J.W., Shin, S.S., Heo, S.H. et al. The accuracy of 64-slice MDCT for determining the perforation site of the gastrointestinal tract: ROC analysis. Abdom Imaging 36, 503–508 (2011). https://doi.org/10.1007/s00261-010-9660-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00261-010-9660-2

Keywords

Navigation