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Imaging of the fetal oral cavity, airway and neck

  • Minisymposium: Pediatric head and neck imaging
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Abstract

Magnetic resonance imaging has proved to be an extraordinarily useful adjunct modality in assessment of the fetal face, oral cavity, head and neck because of its soft-tissue contrast, utility for acquiring more precise planar imaging and the inherent advantage of contrast provided by fluid-filled structures, including the oropharyngeal cavity, nasal passages and vascular structures. In this review, the author presents an organized approach to assessing normal anatomical structures of the fetus. The author presents cystic and solid lesions as well as structural and developmental abnormalities and discusses potential concomitant abnormalities. Prenatal consultation, patient counseling and delivery considerations are included.

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References

  1. Houshmand G, Hosseinzadeh K, Ozolek J (2011) Prenatal magnetic resonance imaging (MRI) findings of a foregut duplication cyst of the tongue: value of real-time MRI evaluation of the fetal swallowing mechanism. J Ultrasound Med 30:843–850

    Article  PubMed  Google Scholar 

  2. Lee DH, Yoon TM, Lee JK, Lim SC (2017) Bronchogenic cyst in the head and neck region. J Craniofac Surg 28:e303–e305

    Article  PubMed  Google Scholar 

  3. Woodfield CA, Levine MS, Rubesin SE et al (2005) Pharyngeal retention cysts: radiographic findings in seven patients. AJR Am J Roentgenol 184:793–796

    Article  PubMed  Google Scholar 

  4. Gilbey P, Amirav I, Luder A (2011) Vallecular cyst: rare cause of failure to thrive without respiratory distress in an infant. J Pediatr 159:869–869.e1

    Article  PubMed  Google Scholar 

  5. Pollock JA, Newton TH, Hoyt WF (1968) Transsphenoidal and transethmoidal encephaloceles. A review of clinical and roentgen features in 8 cases. Radiology 90:442–453

    Article  CAS  PubMed  Google Scholar 

  6. Koral K, Geffner ME, Curran JG (2000) Trans-sphenoidal and sphenoethmoidal encephalocele: report of two cases and review of the literature. Australas Radiol 44:220–224

    Article  CAS  PubMed  Google Scholar 

  7. Rodríguez Tárrega E, Fuster Rojas S, Gómez Portero R et al (2016) Prenatal ultrasound diagnosis of a cyst of the oral cavity: an unusual case of thyroglossal duct cyst located on the tongue base. Case Rep Obstet Gynecol 2016:7816306

    PubMed  PubMed Central  Google Scholar 

  8. Dzieniecka M, Komorowska A, Grzelak-Krzymianowska A, Kulig A (2011) Multiple congenital epuli (congenital granular cell tumours) in the newborn: a case report and review of literature. Pol J Pathol 62:69–71

    PubMed  Google Scholar 

  9. Lee J-M, Kim U-K, Shin S-H (2013) Multiple congenital epulis of the newborn: a case report and literature review. J Pediatr Surg Case Rep 1:32–33

    Article  CAS  Google Scholar 

  10. Kwon Y-D, Kim MS, Seminario AL, Choi SC (2014) From newborn to toddler: the report of two cases with congenital granular cell tumor. J Oral Maxillofac Surg 73:291–294

    Article  PubMed  Google Scholar 

  11. Silva GC, Vieira TC, Vieira JC et al (2007) Congenital granular cell tumor (congenital epulis): a lesion of multidisciplinary interest. Med Oral Patol Oral Cir Bucal 12:E428–E430

    PubMed  Google Scholar 

  12. Chauhan DS, Guruprasad Y, Inderchand S (2011) Congenital nasopharyngeal teratoma with a cleft palate: case report and a 7 year follow up. J Maxillofac Oral Surg 10:253–256

    Article  PubMed  PubMed Central  Google Scholar 

  13. Kirishima M, Yamada S, Shinya M et al (2018) An autopsy case of epignathus (immature teratoma of the soft palate) with intracranial extension but without brain invasion: case report and literature review. Diagn Pathol 13:99

    Article  PubMed  PubMed Central  Google Scholar 

  14. ElSherbiny HM, El-Din MHN, Abdelazim IA et al (2019) Prenatal diagnosis and immediate successful management of isolated fetal epignathus. J Med Ultrasound 27:198–201

    Article  Google Scholar 

  15. Clement K, Chamberlain P, Boyd P, Molyneux A (2001) Prenatal diagnosis of an epignathus: a case report and review of the literature. Ultrasound Obstet Gynecol 18:178–181

    Article  CAS  PubMed  Google Scholar 

  16. Masahata K, Soh H, Tachibana K et al (2019) Clinical outcomes of ex utero intrapartum treatment for fetal airway obstruction. Pediatr Surg Int 35:835–843

    Article  PubMed  Google Scholar 

  17. Agarwal P, Saxena S, Kumar S, Gupta R (2010) Melanotic neuroectodermal tumor of infancy: presentation of a case affecting the maxilla. J Oral Maxillofac Pathol 14:29–32

    Article  PubMed  PubMed Central  Google Scholar 

  18. Reddy ER, Kumar MS, Aduri R, Sreelakshmi N (2013) Melanotic neuroectodermal tumor of infancy: a rare case report. Contemp Clin Dent 4:559–562

    Article  PubMed  PubMed Central  Google Scholar 

  19. Moreau A, Galmiche L, Belhous K et al (2018) Prenatal diagnosis of a melanotic neuroectodermal tumor of infancy (MNTI): a case report with a favorable outcome after chemotherapy failure and incomplete resection. J Pediatr Hematol Oncol 40:320–324

    Article  PubMed  Google Scholar 

  20. Defnet AM, Bagrodia N, Hernandez SL et al (2016) Pediatric lymphatic malformations: evolving understanding and therapeutic options. Pediatr Surg Int 32:425–433

    Article  PubMed  Google Scholar 

  21. Peranteau WH, Iyoob SD, Boelig MM et al (2017) Prenatal growth characteristics of lymphatic malformations. J Pediatr Surg 52:65–68

    Article  PubMed  Google Scholar 

  22. Bagrodia N, Defnet AM, Kandel JJ (2015) Management of lymphatic malformations in children. Curr Opin Pediatr 27:356–363

    Article  PubMed  Google Scholar 

  23. Shamshirsaz AA, Stewart KA, Erfani H et al (2019) Cervical lymphatic malformations: prenatal characteristics and ex utero intrapartum treatment. Prenat Diagn 39:287–292

    Article  PubMed  Google Scholar 

  24. Lee D, Lee JY, Na S, Hwang JY (2014) Huge fetal cervicomediastinal thymic cyst: successful antenatal intervention for vaginal delivery. J Ultrasound Med 33:919–921

    Article  CAS  PubMed  Google Scholar 

  25. Komura M, Kanamori Y, Sugiyama M et al (2010) A pediatric case of life-threatening airway obstruction caused by a cervicomediastinal thymic cyst. Pediatr Radiol 40:1569–1571

    Article  PubMed  Google Scholar 

  26. Lind RC, Hulscher JB, van der Wal JE et al (2010) A very rare case of a giant third branchial pouch remnant discovered in utero. Eur J Pediatr Surg 20:349–351

    Article  CAS  PubMed  Google Scholar 

  27. Patron V, Roudaut PY, Brosset P et al (2012) Right fourth branchial cyst presenting as retropharyngeal collection in a neonate. J Perinatol 32:153–155

    Article  CAS  PubMed  Google Scholar 

  28. Feygin T, Khalek N, Moldenhauer JS (2020) Fetal brain, head and neck tumors: prenatal imaging and management. Prenat Diagn. https://doi.org/10.1002/pd.5722

  29. Peiró JL, Sbragia L, Scorletti F et al (2016) Management of fetal teratomas. Pediatr Surg Int 32:635–647

    Article  PubMed  Google Scholar 

  30. Wolfe K, Lewis D, Witte D et al (2013) Fetal cervical teratoma: what is the role of fetal MRI in predicting pulmonary hypoplasia? Fetal Diagn Ther 33:252–256

    Article  PubMed  Google Scholar 

  31. Güzelmansur I, Aksoy HT, Hakverdi S et al (2011) Fetal cervical neuroblastoma: prenatal diagnosis. Case Rep Med 2011:529749

    Article  PubMed  PubMed Central  Google Scholar 

  32. Kolbe AB, Merrow AC, Eckel LJ et al (2019) Congenital hemangioma of the face-value of fetal MRI with prenatal ultrasound. Radiol Case Rep 14:1443–1446

    Article  PubMed  PubMed Central  Google Scholar 

  33. Doğer E, Ceylan Y, Çakıroğlu AY, Çalışkan E (2015) Prenatal diagnosis and management of a fetal neck mass. J Turk Ger Gynecol Assoc 16:118–120

    Article  PubMed  PubMed Central  Google Scholar 

  34. Nemec U, Nemec SF, Brugger PC et al (2015) Normal mandibular growth and diagnosis of micrognathia at prenatal MRI. Prenat Diagn 35:108–116

    Article  PubMed  Google Scholar 

  35. Rogers-Vizena CR, Mulliken JB, Daniels KM, Estroff JA (2016) Prenatal features predictive of Robin sequence identified by fetal magnetic resonance imaging. Plast Reconstr Surg 137:999e–1006e

    Article  CAS  PubMed  Google Scholar 

  36. Paladini D, Morra T, Teodoro A et al (1999) Objective diagnosis of micrognathia in the fetus: the jaw index. Obstet Gynecol 93:382–386

    CAS  PubMed  Google Scholar 

  37. Rotten D, Levaillant JM, Martinez H et al (2002) The fetal mandible: a 2D and 3D sonographic approach to the diagnosis of retrognathia and micrognathia. Ultrasound Obstet Gynecol 19:122–130

    Article  CAS  PubMed  Google Scholar 

  38. Kooiman TD, Calabrese CE, Didier R et al (2018) Micrognathia and oropharyngeal space in patients with Robin sequence: prenatal MRI measurements. J Oral Maxillofac Surg 76:408–415

    Article  PubMed  Google Scholar 

  39. Resnick CM, Kooiman TD, Calabrese CE et al (2018) An algorithm for predicting Robin sequence from fetal MRI. Prenat Diagn 38:357–364

    Article  PubMed  Google Scholar 

  40. Society for Maternal–Fetal Medicine, Benacerraf BR, Bromley B, Jelin AC (2019) Micrognathia. Am J Obstet Gynecol 221:B13–B15

    Article  Google Scholar 

  41. Mouthon L, Busa T, Bretelle F et al (2019) Prenatal diagnosis of micrognathia in 41 fetuses: retrospective analysis of outcome and genetic etiologies. Am J Med Genet A 179:2365–2373

    Article  PubMed  Google Scholar 

  42. Overcash RT, Marc-Aurele KL, Hull AD, Ramos GA (2016) Maternal iodine exposure: a case of fetal goiter and neonatal hearing loss. Pediatrics 137:e20153722

    Article  PubMed  Google Scholar 

  43. Panaitescu AM, Nicolaides K (2018) Fetal goitre in maternal Graves' disease. Acta Endocrinol 14:85–89

    CAS  Google Scholar 

  44. Figueiredo CM, Falcão I, Vilaverde J et al (2018) Prenatal diagnosis and management of a fetal goiter hypothyroidism due to dyshormonogenesis. Case Rep Endocrinol 2018:9564737

    PubMed  PubMed Central  Google Scholar 

  45. Delay F, Dochez V, Biquard F et al (2018) Management of fetal goiters: 6-year retrospective observational study in three prenatal diagnosis and treatment centers of the Pays De Loire Perinatal Network. J Matern Fetal Neonatal Med 4:1–191

  46. Stoll C, Alembik Y, Dott B, Roth M-P (2016) Associated anomalies in cases with anotia and microtia. Eur J Med Genet 59:607–614

    Article  PubMed  Google Scholar 

  47. Bijok J, Kucińska-Chahwan A, Gielniewska-Michalczyk L et al (2019) The location of the fetal ears: a hint for prenatal diagnosis of agnathia-otocephaly complex. J Clin Ultrasound 47:369–371

    Article  PubMed  Google Scholar 

  48. Abukhalaf SA, Zalloum JS, Al Hammouri A et al (2020) Congenital arrhinia: a case report and literature review. Int J Pediatr Otorhinolaryngol 135:110083

    Article  PubMed  Google Scholar 

  49. Li X, Zhang L, Wang F (2015) Prenatal diagnosis of total arhinia by MRI. Jpn J Radiol 33:672–674

    Article  PubMed  Google Scholar 

  50. Blask AR, Rubio EI, Chapman KA et al (2018) Severe nasomaxillary hypoplasia (binder phenotype) on prenatal US/MRI: an important marker for the prenatal diagnosis of chondrodysplasia punctata. Pediatr Radiol 48:979–991

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Eva Ilse Rubio.

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Rubio, E.I. Imaging of the fetal oral cavity, airway and neck. Pediatr Radiol 51, 1122–1133 (2021). https://doi.org/10.1007/s00247-020-04851-6

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  • DOI: https://doi.org/10.1007/s00247-020-04851-6

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