Abstract
Lumpy skin disease (LSD) is a highly infectious and economically devastating viral disease of cattle. It is caused by Lumpy Skin Disease Virus (LSDV) belonging to the genus Capripoxvirus and family Poxviridae. The origin of lumpy skin disease has been traced to Zambia, (an African nation) in Southern part during the year 1929. The first reported case of LSD besides Africa was from Israel, a Middle Eastern nation, thus proving inter-continental spread. Subsequently, the disease entered Middle East, Eastern Europe and Asia with numerous outbreaks in the recent years. LSD has emerged as a significant concern in the Indian sub-continent, due to outbreaks reported in countries such as Bangladesh, India, China in 2019. In the following years, other South and East Asian countries like Taipei, Nepal, Sri Lanka, Myanmar, Bhutan, Vietnam, Hong Kong, Thailand, Malaysia, Laos, Cambodia, Pakistan, Indonesia and Singapore also faced severe outbreaks. At present, LSD is considered to be an emerging disease in the Indian sub-continent due to the recent status of disease. Considering the global scenario, LSDV is changing its transmission dynamics as evidenced by a shift in its epidemiology. As a result of high morbidity and mortality rate among cattle, the current outbreaks have been a major cause of socio-economic catastrophe. This contagious viral disease has eminent repercussions as the estimated monetary damage incurred is quite high. Despite having networked surveillance and comprehensive databases, the recurring outbreaks have raised major concern among researchers. Therefore, this review offers brief insights into the emergence of LSDV by amalgamating the newest literature related to its biology, transmission, clinico-pathology, epidemiology, prevention strategies, and economic consequences. Additionally, we have also provided the epidemiological insights of the recent outbreaks with detailed state wise studies.
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References
Abdallah FM, El Damaty HM, Kotb GF (2018) Sporadic cases of lumpy skin disease among cattle in Sharkia province, Egypt: Genetic characterization of lumpy skin disease virus isolates and pathological findings. Vet World 11(8):1150–1158
Abera Z, Degefu H, Gari G, Kidane M (2015) Sero-prevalence of lumpy skin disease in selected districts of West Wollega zone. Ethiopia BMC Vet Res 11:135. https://doi.org/10.1186/s12917-015-0432-7
Abutarbush SM (2017) Lumpy skin disease (knopvelsiekte, pseudo-urticaria, neethling virus disease, exanthema nodularis bovis). Emerg Re-Emerg Infect Dis Livest. https://doi.org/10.1007/978-3-319-47426-7-14
Abutarbush SM, Ababneh MM, Al Zoubi IG, Al Sheyab OM, Al Zoubi MG, Alekish MO, Al Gharabat RJ (2015) Lumpy skin disease in Jordan: disease emergence, clinical signs, complications and preliminary-associated economic losses. Transbound Emerg Dis 62(5):549–554. https://doi.org/10.1111/tbed.12177
Abutarbush SM, Hananeh WM, Ramadan W, Al Sheyab OM, Alnajjar AR, Al Zoubi IG, Knowles NJ, Bachanek-Bankowska K, Tuppurainen ES (2016) Adverse reactions to field vaccination against lumpy skin disease in Jordan. Transbound Emerg Dis 63(2):e213–e219
Acharya KP, Subedi D (2020) First outbreak of lumpy skin disease in Nepal. Transbound Emerg Dis 67(6):2280–2281. https://doi.org/10.1111/tbed.13815
Akther M, Akter SH, Sarker S, Aleri JW, Annandale H, Abraham S, Uddin JM (2023) Global burden of lumpy skin disease, outbreaks, and future challenges. Viruses 15(9):1861
Alexander RA, Plowright W, Haig DA (1957) Cytopathogenic agents associated with lumpy skin disease of cattle. Bull Epizoot Dis Afr 5:489–492
Ali AA, Esmat M, Attia H, Selim A, Abdel-Hamid YM (1990) Clinical and pathological studies on lumpy skin disease in Egypt. Vet Rec 127(22):549–550
Al-Salihi K (2014) Lumpy skin disease: review of literature. Mirror Res Vet Sci Anim 3(3):6–23
Al-Salihi KA, Hassan IQ (2015) Lumpy skin disease in Iraq: study of the disease emergence. Transbound Emerg Dis 62:457–462. https://doi.org/10.1111/tbed.12386
Awadin W, Hussein H, Elseady Y, Babiuk S, Furuoka H (2011) Detection of lumpy skin disease virus antigen and genomic DNA in formalin-fixed paraffin-embedded tissues from an Egyptian outbreak in 2006. Transbound Emerg Dis 58(5):451–457. https://doi.org/10.1111/j.1865-1682.2011.01238.x
Ayelet G, Abate Y, Sisay T, Nigussie H, Gelaye E, Jemberie S, Asmare K (2013) Lumpy skin disease: preliminary vaccine efficacy assessment and overview on outbreak impact in dairy cattle at Debre Zeit, central Ethiopia. Antiviral Res 98(2):261–265. https://doi.org/10.1016/j.antiviral.2013.02.008
Babiuk S, Bowden TR, Boyle DB, Wallace DB, Kitching RP (2008) Capripoxviruses: an emerging worldwide threat to sheep, goats and cattle. Transbound Emerg Dis 55(7):263–272. https://doi.org/10.1111/j.1865-1682.2008.01043.x
Babiuk S (2018) Genome. In: Lumpy skin disease. Springer, Cham. https://doi.org/10.1007/978-3-319-92411-3_8
Badhy SC, Chowdhury MGA, Settypalli TBK, Cattoli G, Lamien CE, Fakir MAU, Akter S, Osmani MG, Talukdar F, Begum N, Khan IA (2021) Molecular characterization of lumpy skin disease virus (LSDV) emerged in Bangladesh reveals unique genetic features compared to contemporary field strains. BMC Vet Res 17(1):1–11. https://doi.org/10.1186/s12917-021-02751-x
Beard PM (2016) Lumpy skin disease: a direct threat to Europe. Vet Rec 178(22):557–558. https://doi.org/10.1136/vr.i2800
Ben-Gera J, Klement E, Khinich E, Stram Y, Shpigel NY (2015) Comparison of the efficacy of Neethling lumpy skin disease virus and x10RM65 sheep-pox live attenuated vaccines for the prevention of lumpy skin disease—the results of a randomized controlled field study. Vaccine 33(38):4837–4842. https://doi.org/10.1016/j.vaccine.2015.07.071
Bhadauria P, Brar PK, Makhdoomi DM, Singh TB, Singh S, Gupta R, Singh R (2023) Lumpy skin disease: emerging threat to livestock industry. ICAR- ATARI, Ludhiana. https://atariz1.icar.gov.in/pdf/Lumpy%20Skin%20Disease.pdf.
Bhatt L, Bhoyar RC, Jolly B, Israni R, Vignesh H, Scaria V, Sivasubbu S (2023) The genome sequence of lumpy skin disease virus from an outbreak in India suggests a distinct lineage of the virus. Adv Virol 168(3):81. https://doi.org/10.1007/s00705-023-05705-w
Bianchini J, Simons X, Humblet MF, Saegerman C (2023) Lumpy skin disease: a systematic review of mode of transmission, risk of emergence and risk entry pathway. Viruses 15(8):1622. https://doi.org/10.3390/v15081622
Boshra H, Truong T, Nfon C, Bowden TR, Gerdts V, Tikoo S, Babiuk LA, Kara P, Mather A, Wallace DB, Babiuk S (2015) A lumpy skin disease virus deficient of an IL-10 gene homologue provides protective immunity against virulent capripoxvirus challenge in sheep and goats. Antiviral Res 123:39–49. https://doi.org/10.1016/j.antiviral.2015.08.016
Boumart Z, Daouam S, Belkourati I, Rafi L, Tuppurainen E, Tadlaoui KO, El Harrak M (2016) Comparative innocuity and efficacy of live and inactivated sheeppox vaccines. BMC Vet Res 12(1):1–6. https://doi.org/10.1186/s12917-016-0754-0
Brenner J, Bellaiche M, Gross E, Elad D, Oved Z, Haimovitz M, Wasserman A, Friedgut O, Stram Y, Bumbarov V, Yadin H (2009) Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: statutory challenge. Vaccine 27(10):1500–1503. https://doi.org/10.1016/j.vaccine.2009.01.020
Brody AL (1936) The transmission of fowl-pox. CABI Databases 195:37
Buller RM, Arif BM, Black DN, Dumbell KR, Esposito JJ, Lefkowitz EJ, McFadden G, Moss B, Mercer AA, Moyer RW, Skinner MA, Tripathy DN (2005) Family Poxviridae. In: Fauquet CM, Mayo MA, Maniloff J, Desselberger U, Ball LA (eds) Virus taxonomy: classification and nomenclature of viruses. Eighth report of the international committee on taxonomy of viruses. Elsevier Academic Press, San Diego, pp 117–133
Calistri P, DeClercq K, Gubbins S, Klement E, Stegeman A, Cortiñas Abrahantes J, Antoniou SE, Broglia A, Gogin A, European Food Safety Authority (EFSA) (2019) Lumpy skin disease: III. Data collection and analysis. EFSA J Eur Food Saf Auth 17(3):e05638. https://doi.org/10.2903/j.efsa.2019.5638
Coetzer JAW, Tuppurainen E (2004) Lumpy skin disease. Infect Dis Livest 2:1268–1276
Constable PD, Hinchcliff KW, Done SH, Grünberg W (2016) Veterinary medicine: a textbook of the diseases of cattle, horses, sheep, pigs and goats. Elsevier Health Sciences
Department of Animal husbandry and dairying (DAHD) (2023) https://dahd.nic.in/sites/default/filess/MonthlySummaryMay2023-DAHD-English.pdf.
Dao TD, Tran LH, Nguyen HD, Hoang TT, Nguyen GH, Tran KVD, Nguyen HX, Van Dong H, Bui AN, Bui VN (2022) Characterization of lumpy skin disease virus isolated from a giraffe in Vietnam. Transbound Emerg Dis 69(5):3268–3272. https://doi.org/10.1111/tbed.14583
Dubie T, Hussen Abegaz F, Dereje B, Negash W, Hamid M (2022) Seroprevalence and associated risk factors of lumpy skin disease of cattle in selected districts of Afar Region Ethiopia. Vet Med 13:191–199
EFSA Panel on Animal Health and Welfare (AHAW), Nielsen SS, Alvarez J, Bicout DJ, Calistri P, Canali E, Drewe JA, Garin-Bastuji B, Gonzales Rojas JL, Gortázar Schmidt C, Herskin M (2022) Assessment of the control measures for category A diseases of animal health law: lumpy skin disease. EFSA J 20(1):07121. https://doi.org/10.2903/j.efsa.2022.7121
El-Nahas EM, El-Habbaa AS, El-Bagoury GF, Radwan ME (2011) Isolation and identification of lumpy skin disease virus from naturally infected buffaloes at Kaluobia. Egypt Glob Vet 7(3):234–237
Eom HJ, Lee ES, Yoo HS (2023) Lumpy skin disease as an emerging infectious disease. J Vet Sci. https://doi.org/10.4142/jvs.23016
European Food Safety Authority (EFSA), Calistri P, DeClercq K, De Vleeschauwer A, Gubbins S, Klement E, Stegeman A, Cortiñas Abrahantes J, Antoniou SE, Broglia A, Gogin A (2018) Lumpy skin disease: scientific and technical assistance on control and surveillance activities. EFSA J Eur Food Saf Auth 16(10):e05452. https://doi.org/10.2903/j.efsa.2018.5452
European Food Safety Authority (EFSA), Calistri P, De Clercq K, Gubbins S, Klement E, Stegeman A, Cortiñas Abrahantes J, Marojevic D, Antoniou SE, Broglia A (2020) Lumpy skin disease epidemiological report IV: data collection and analysis. EFSA J Eur Food Saf Auth 18(2):e06010. https://doi.org/10.2903/j.efsa.2020.6010
FAO (2022) Lumpy skin disease [LSD] field manual. https://www.fao.org/3/i7330e/i7330e.pdf. Accessed 27 Dec 2022
Fay PC, Wijesiriwardana N, Munyanduki H, Sanz-Bernardo B, Lewis I, Haga IR, Moffat K, van Vliet AHM, Hope J, Graham SP, Beard PM (2022) The immune response to lumpy skin disease virus in cattle is influenced by inoculation route. Front Immunol 28(13):1051008. https://doi.org/10.3389/fimmu.2022.1051008
Fenner F, Day MF, Woodroofe GM (1952) The mechanism of the transmission of myxomatosis in the European rabbit (Oryctolagus cuniculus) by the mosquito Aedes aegypti. Aust J Exp Biol Med Sci 30(2):139–152. https://doi.org/10.1038/icb.1952.13
Gari G, Abie G, Gizaw D, Wubete A, Kidane M, Asgedom H, Bayissa B, Ayelet G, Oura CA, Roger F, Tuppurainen ES (2015) Evaluation of the safety, immunogenicity and efficacy of three capripoxvirus vaccine strains against lumpy skin disease virus. Vaccine 33(28):3256–3261. https://doi.org/10.1016/j.vaccine.2015.01.035
Gupta T, Patial V, Bali D, Angaria S, Sharma M, Chahota R (2020) A review: lumpy skin disease and its emergence in India. Vet Res Commun 44:111–118. https://doi.org/10.1007/s11259-020-09780-1
Hakobyan V, Sargsyan K, Kharatyan S, Elbakyan H, Sargsyan V, Markosyan T, Vardanyan T, Badalyan M, Achenbach JE (2023) The Serological response in cattle following administration of a heterologous Sheep pox virus strain vaccine for protection from lumpy skin disease. Curr Situat Armen Vet Sci 10(2):102. https://doi.org/10.3390/vetsci10020102
Hamdi J, Bamouh Z, Jazouli M, Boumart Z, Tadlaoui KO, Fihri OF, El Harrak M (2020) Experimental evaluation of the cross-protection between Sheeppox and bovine lumpy skin vaccines. Sci Rep 10(1):8888. https://doi.org/10.1038/s41598-020-65856-7
Hasib FMY, Islam MS, Das T, Rana EA, Uddin MH, Bayzid M, Nath C, Hossain MA, Masuduzzaman M, Das S, Alim MA (2021) Lumpy skin disease outbreak in cattle population of Chattogram. Bangladesh Vet Med Sci 7(5):1616–1624. https://doi.org/10.1002/vms3.524
Hosamani M, Mondal B, Tembhurne PA, Bandyopadhyay SK, Singh RK, Rasool TJ (2004) Differentiation of sheep pox and goat poxviruses by sequence analysis and PCR-RFLP of P32 gene. Virus Genes 29(1):73–80. https://doi.org/10.1023/B:VIRU.0000032790.16751.13
Issimov A, Kushaliyev K, Abekeshev N, Molla W, Rametov N, Bayantassova S, Zhanabayev A, Paritova A, Shalmenov M, Ussenbayev A, Kemeshov Z, Baikadamova G, White P (2022) Risk factors associated with lumpy skin disease in cattle in West Kazakhstan. Prev Vet Med 207:105660. https://doi.org/10.1016/j.prevetmed.2022.105660
Jasreet Kaur. Lumpy skin disease spreads among cattle in Uttar Pradesh; massive vaccination campaign launched to curb outbreak. Jagran Josh; (2023). Available from: (https://english.jagran.com/uttar-pradesh/lumpy-skin-disease-spreads-among-cattle-in-uttar-pradesh-massive-vaccination-campaign-launched-to-curb-outbreak-10100493).
Kasem S, Saleh M, Qasim I, Hashim O, Alkarar A, Abu-Obeida A, Gaafer A, Hussien R, Al-Sahaf A, Al-Doweriej A, Bayoumi F, Hodhood A, Abdelatif M (2018) Outbreak investigation and molecular diagnosis of lumpy skin disease among livestock in Saudi Arabia 2016. Transbound Emerg Dis 65(2):e494–e500. https://doi.org/10.1111/tbed.12769
Kayesh MEH, Hussan MT, Hashem MA, Eliyas M, Anower AM (2020) Lumpy skin disease virus infection: an emerging threat to cattle health in Bangladesh. Hosts Viruses 7(4):97. https://doi.org/10.17582/journal.hv/2020/7.4.97.108
Kilham L, Dalmat HT (1955) Host-virus-mosquito relations of Shope fibromas in cottontail rabbits. Am J Hyg 61(1):45–54. https://doi.org/10.1093/oxfordjournals.aje.a119737
King AM, Adams MJ, Carstens EB, Lefkowitz EJ (2012). Virus taxonomy. Ninth report of the International Committee on Taxonomy of Viruses, vol 9. Elsevier, Amsterdam, p 1327
Ko YS, Oh Y, Lee TG, Bae DY, Tark D, Cho HS (2022) Serological and molecular prevalence of lumpy skin disease virus in Korean water deer, native and dairy cattle in Korea. Korean J Vet Serv 45(2):133–137. https://doi.org/10.7853/kjvs.2022.45.2.133
Kumar N, Tripathi BN (2022) A serious skin virus epidemic swee** through the Indian subcontinent is a threat to the livelihood of farmers. Virulence 13(1):1943–1944. https://doi.org/10.1080/21505594.2022.2141971
Kumar N, Barua S, Kumar R, Khandelwal N, Kumar A, Verma A, Singh L, Godara B, Chander Y, Kumar G, Riyesh T, Sharma DK, Pathak A, Kumar S, Dedar RK, Mehta V, Gaur M, Bhardwaj B, Vyas V, Chaudhary S, Tripathi BN (2023a) Evaluation of the safety, immunogenicity and efficacy of a new live-attenuated lumpy skin disease vaccine in India. Virulence 14(1):2190647. https://doi.org/10.1080/21505594.2023.2190647
Kumar R, Godara B, Chander Y, Kachhawa JP, Dedar RK, Verma A, Riyesh T, Pal Y, Barua S, Tripathi BN, Kumar N (2023b) Evidence of lumpy skin disease virus infection in camels. Acta Trop 242:106922. https://doi.org/10.1016/j.actatropica.2023.106922
Lamien CE, Le Goff C, Silber R, Wallace DB, Gulyaz V, Tuppurainen E, Madani H, Caufour P, Adam T, El Harrak M, Luckins AG, Albina E, Diallo A (2011) Use of the Capripoxvirus homologue of Vaccinia virus 30 kDa RNA polymerase subunit (RPO30) gene as a novel diagnostic and genoty** target: development of a classical PCR method to differentiate Goat poxvirus from Sheep poxvirus. Vet Microbiol 149(1–2):30–39. https://doi.org/10.1016/j.vetmic.2010.09.038
Lu G, **e J, Luo J, Shao R, Jia K, Li S (2021) Lumpy skin disease outbreaks in China, since 3 August 2019. Transbound Emerg Dis 68(2):216–219. https://doi.org/10.1111/tbed.13898
Lubinga JC, Tuppurainen ES, Stoltsz WH, Ebersohn K, Coetzer JA, Venter EH (2013) Detection of lumpy skin disease virus in saliva of ticks fed on lumpy skin disease virus-infected cattle. Exp Appl Acarol 61(1):129–138. https://doi.org/10.1007/s10493-013-9679-5
Lumpy skin disease outbreak in India, Wikipedia (2022). https://en.wikipedia.org/wiki/Lumpy_skin_disease_outbreak_in_India#:~:text=The%202022%20lumpy%20skin%20disease,between%20July%20and%2023%20September.
MacLachlan NJ, Dubovi EJ (2011) Fenner’s veterinary virology, 4th edn. Academic, London, Boston
Manjunatha Reddy GB, Pabbineedi SM, Nagaraj S, Bijalwan S, Tadakod S, Bhutia Z, Palmu D, Rai S, Bhutia PD, Bhutia PT, Shenga E, Gulati BR (2023) Lumpy skin disease (LSD) in Yak (Bos grunniens): an evidence of species spillover from cattle in India. Microorganisms 11(12):2823. https://doi.org/10.3390/microorganisms11122823
Mathivanan E, Raju K, Murugan R (2023) Outbreak of Lumpy skin disease in India 2022-an emerging threat to livestock & livelihoods. Glob Biosecurity. https://doi.org/10.31646/gbio.187
Menasherow S, Rubinstein-Giuni M, Kovtunenko A, Eyngor Y, Fridgut O, Rotenberg D, Khinich Y, Stram Y (2014) Development of an assay to differentiate between virulent and vaccine strains of lumpy skin disease virus (LSDV). J Virol Methods 199:95–101. https://doi.org/10.1016/j.jviromet.2013.12.013
Molini U, Boshoff E, Niel AP, Phillips J, Khaiseb S, Settypalli TBK, Dundon WG, Cattoli G, Lamien CE (2021) Detection of lumpy skin disease virus in an asymptomatic eland (Taurotragus oryx) in Namibia. J Wildl Dis 57(3):708–711. https://doi.org/10.7589/JWD-D-20-00181
Molla W, Frankena K, Gari G, Kidane M, Shegu D, de Jong MCM (2018) Seroprevalence and risk factors of lumpy skin disease in Ethiopia. Prev Vet Med 160:99–104. https://doi.org/10.1016/j.prevetmed.2018.09.029
Namazi F, Khodakaram Tafti A (2021) Lumpy skin disease, an emerging transboundary viral disease: a review. Vet Med Sci 7(3):888–896. https://doi.org/10.1002/vms3.434
National lumpy skin disease action plan (2022). Available online:https://www.agriculture.gov.au/sites/default/files/documents/lsd-national-action-plan.pdf.
Ochwo S, VanderWaal K, Munsey A, Nkamwesiga J, Ndekezi C, Auma E, Mwiine FN (2019) Seroprevalence and risk factors for lumpy skin disease virus seropositivity in cattle in Uganda. BMC Vet Res 15:1–9. https://doi.org/10.1186/s12917-019-1983-9
Oie A (2008) Manual of diagnostic tests and vaccines for terrestrial animals. Office International Des Epizooties, Paris, France, pp 1092–1106
Orlova ES, Shcherbakov AV, Diev VI, Zakharov VM (2006) Differentiation of capripoxvirus species and strains by polymerase chain reaction. Mol Biol 40:139–145
Owan KDS (1959) Observations on the epizootiology of lumpy skin disease during the first year of its occurrence in Kenya. Bull Epizoot Dis Afr 7:7–20
Pandey G, Pathak CR, Sadaula A, Bastakoti R, Hamal P, Khanal P, Paudel S (2021) Molecular and Serological Detection of Lumpy Skin Disease in Cattle of Western Chitwan, Nepal. In: Proceedings of 12th National Workshop on Livestock and Fisheries Research in Nepal on, p 3–4
Paslaru AI, Verhulst NO, Maurer LM, Brendle A, Pauli N, Vögtlin A, Renzullo S, Ruedin Y, Hoffmann B, Torgerson PR, Mathis A (2021) Potential mechanical transmission of lumpy skin disease virus (LSDV) by the stable fly (Stomoxys calcitrans) through regurgitation and defecation. Curr Res Insect Sci 1:100007. https://doi.org/10.1016/j.cris.2020.100007
Porco A, Chea S, Sours S, Nou V, Groenenberg M, Agger C, Tum S, Chhuon V, Sorn S, Hong C, Davis B, Davis S, Ken S, Olson SH, Fine AE (2023) Case report: lumpy skin disease in an endangered wild banteng (Bos javanicus) and initiation of a vaccination campaign in domestic livestock in Cambodia. Front Vet Sci 10:1228505. https://doi.org/10.3389/fvets.2023.1228505
Quinn PJ, Markey BK, Leonard FC, Fitzpatrick ES, Fanning S, Fitzpatrick ES (2016) Zygomycetes of veterinary importance. In: Ames IA (ed) Concise review of veterinary microbiology, 2nd edn. Blackwell, pp 108–109
Rai A, Rawat SS, Chopra H, Singh I, Emran TB (2023) Lumpy skin disease: the underestimated epidemic for cattle in India. Int J Surg Glob Health 6(5):0282. https://doi.org/10.1097/GH9.0000000000000282
Ratyotha K, Prakobwong S, Piratae S (2022) Lumpy skin disease: a newly emerging disease in Southeast Asia. Vet World 15(12):2764
Rinchen S (2022) Descriptive epidemiology of the first lumpy skin disease outbreak in Bhutan. Bhutan J Anim Sci 6(1):46–51
Roche X, Rozstalnyy A, TagoPacheco D, Pittiglio C, Kamata A, Beltran Alcrudo D, Sumption K (2021) Introduction and spread of lumpy skin disease in South, East and Southeast Asia: qualitative risk assessment and management. Food & Agriculture Org
Salib FA, Osman AH (2011) Incidence of lumpy skin disease among Egyptian cattle in Giza Governorate Egypt. Vet World 4(4):162–167
Sameea Yousefi P, Mardani K, Dalir-Naghadeh B, Jalilzadeh-Amin G (2017) Epidemiological study of lumpy skin disease outbreaks in North-western Iran. Transbound Emerg Dis 64(6):1782–1789. https://doi.org/10.1111/tbed.12565
Sanganagouda K, Nagraja K, Sajjanar B, Kounin S, Gomes AR, Pavithra BH, Lalasangi S, Sumathi BR, Murag S, Shankar BP, KR, A.K (2023) Molecular characterization, phylogenetic analysis and viral load quantification of Lumpy Skin Disease Virus in Cattle. https://doi.org/10.21203/rs.3.rs-3220257/v1.
Sanjeeb Mukherjee (2023) Lumpy skin disease returns; over 10,000 active cases reported till May 18. Business Standard. Available from: (https://www.business-standard.com/india-news/lumpy-skin-disease-returns-over-10-000-active-cases-reported-till-may-18-123052000222_1.html).
Selim A, Manaa E, Khater H (2021) Seroprevalence and risk factors for lumpy skin disease in cattle in Northern Egypt. Trop Anim Health Prod 53(3):350. https://doi.org/10.1007/s11250-021-02786-0
Sethi RK, Senapati SK, Selim AM, Acharya AP, Mishra C, Das M, Hegazy YM, Biswal SS (2022) Molecular epidemiology of lumpy skin disease outbreak in Odisha. India Vet Res Commun 46(3):711–717. https://doi.org/10.1007/s11259-022-09886-8
Şevik M, Doğan M (2017) Epidemiological and molecular studies on lumpy skin disease outbreaks in Turkey during 2014–2015. Transbound Emerg Dis 64(4):1268–1279. https://doi.org/10.1111/tbed.12501
Sharma B, Negi BS, Pandey AB, Bandyopadhyay SK, Shankar H, Yadav MP (1988) Detection of goat pox antigen and antibody by the counter immunoelectrophoresis test. Trop Anim Health Prod 20(2):109–113. https://doi.org/10.1007/bf02242237
Shimshony A, Economides P (2006) Disease prevention and preparedness for animal health emergencies in the Middle East. Revue Scientifique Et Technique Int off Epizoot 25(1):253–269. https://doi.org/10.20506/rst.25.1.1667
Singh AP, Dangi N, Singh P, Singh VK, Prabhu SN, Gangwar NK, Biswas SK (2024) Diagnostic utility of intranodular saline lavage in TaqMan probe-based real-time PCR diagnosis of lumpy skin disease. Emerg Anim Species 10:100037. https://doi.org/10.1016/j.eas.2023.100037
Sprygin A, Pestova Y, Wallace DB, Tuppurainen E, Kononov AV (2019) Transmission of lumpy skin disease virus: a short review. Virus Res 269:197637. https://doi.org/10.1016/j.virusres.2019.05.015
Sprygin A, Mazloum A, Van Schalkwyk A, Krotova A, Bydovskaya O, Prokhvatilova L, Chvala I (2023) Development and application of a real-time polymerase chain reaction assay to detect lumpy skin disease virus belonging to the Kenyan sheep and goat pox group. BMC Res Notes 16(1):247. https://doi.org/10.1186/s13104-023-06502-z
Sreedevi B, Rajesh K (2021) Clinico-molecular diagnosis and characterization of bovine lumpy skin disease virus in Andhra Pradesh, India. Trop Anim Health Prod. https://doi.org/10.1007/s11250-021-02872-3
Stubbs S, Oura CA, Henstock M, Bowden TR, King DP, Tuppurainen ES (2012) Validation of a high-throughput real-time polymerase chain reaction assay for the detection of capripoxviral DNA. J Virol Methods 179(2):419–422. https://doi.org/10.1016/j.jviromet.2011.11.015
Sudhakar SB, Mishra N, Kalaiyarasu S, Jhade SK, Hemadri D, Sood R, Bal GC, Nayak MK, Pradhan SK, Singh VP (2020) Lumpy skin disease (LSD) outbreaks in cattle in Odisha state, India in August 2019: Epidemiological features and molecular studies. Transbound Emerg Dis 67(6):2408–2422. https://doi.org/10.1111/tbed.13579
Sudhakar SB, Mishra N, Kalaiyarasu S, Jhade SK, Singh VP (2022) Genetic and phylogenetic analysis of lumpy skin disease viruses (LSDV) isolated from the first and subsequent field outbreaks in India during 2019 reveals close proximity with unique signatures of historical Kenyan NI-2490/Kenya/KSGP-like field strains. Transbound Emerg Dis 69(4):e451–e462. https://doi.org/10.1111/tbed.14322
Sudhakar SB, Mishra N, Kalaiyarasu S, Ahirwar K, Chatterji S, Parihar O, Singh VP, Sanyal A (2023) Lumpy skin disease virus infection in free-ranging Indian Gazelles (Gazella bennettii), Rajasthan. India Emerg Infect Dis 29(7):1407–1410. https://doi.org/10.3201/eid2907.230043
Thomas AD, Mare CVE (1945) Knopvelsiekte. J S Afr Vet Assoc 16:36–43
Tran HTT, Truong AD, Dang AK, Ly DV, Nguyen CT, Chu NT, Hoang TV, Nguyen HT, Nguyen VT, Dang HV (2021) Lumpy skin disease outbreaks in vietnam, 2020. Transbound Emerg Dis 68(3):977–980. https://doi.org/10.1111/tbed.14022
Tripathy DW, Hanson LE, Crandell RA (1981) Pox viruses of veterinary importance. Comparative diagnosis of virus diseases. Academic Press, London, pp 267–346
Tulman ER, Afonso CL, Lu Z, Zsak L, Kutish GF, Rock DL (2001) Genome of lumpy skin disease virus. J Virol 75(15):7122–7130. https://doi.org/10.1128/jvi.75.15.7122-7130.2001
Tuppurainen ES, Venter EH, Coetzer JA (2005) The detection of lumpy skin disease virus in samples of experimentally infected cattle using different diagnostic techniques. Onderstepoort J Vet Res 72(2):153–164. https://doi.org/10.4102/ojvr.v72i2.213
Tuppurainen ES, Lubinga JC, Stoltsz WH, Troskie M, Carpenter ST, Coetzer JA, Venter EH, Oura CA (2013) Evidence of vertical transmission of lumpy skin disease virus in Rhipicephalus decoloratus ticks. Ticks Tick-Borne Dis 4(4):329–333. https://doi.org/10.1016/j.ttbdis.2013.01.006
Tuppurainen ES, Venter EH, Coetzer JA, Bell-Sakyi L (2015) Lumpy skin disease: attempted propagation in tick cell lines and presence of viral DNA in field ticks collected from naturally-infected cattle. Ticks Tick-Borne Dis 6(2):134–140. https://doi.org/10.1016/j.ttbdis.2014.11.002
Tuppurainen ESM, Venter EH, Shisler JL, Gari G, Mekonnen GA, Juleff N, Lyons NA, De Clercq K, Upton C, Bowden TR, Babiuk S, Babiuk LA (2017a) Review: capripoxvirus diseases: current status and opportunities for control. Transbound Emerg Dis 64(3):729–745. https://doi.org/10.1111/tbed.12444
Tuppurainen E, Dietze K, Wolff J, Bergmann H, Beltran-Alcrudo D, Fahrion A, Lamien CE, Busch F, Sauter-Louis C, Conraths FJ, De Clercq K, Hoffmann B, Knauf S (2021) Review: vaccines and vaccination against lumpy skin disease. Vaccines 9(10):1136. https://doi.org/10.3390/vaccines9101136
Tuppurainen ESM, Alexandrov T, Beltrán‐Alcrudo D (2017) Lumpy skin disease field manual–A manual for veterinarians. Food and Agriculture Organization of the United Nations (FAO). Animal Production and Health Manual Place. http://www.fao.org/ag/againfo/home/en/news_archive/2017_New_field_manual_on_lumpy-skin-disease.html.
Uzar S, Sarac F, Gulyaz V, Enul H, Yılmaz H, Turan N (2022) Comparison and efficacy of two different sheep pox vaccines prepared from the Bakırköy strain against lumpy skin disease in cattle. Clin Exp Vaccin Res 11(1):1–11. https://doi.org/10.7774/cevr.2022.11.1.1
Venkatesan G, Balamurugan V, Yogisharadhya R, Kumar A, Bhanuprakash V (2012) Differentiation of sheeppox and goatpox viruses by polymerase Chain reaction-restriction fragment length polymorphism. Virologica Sinica 27(6):353–359. https://doi.org/10.1007/s12250-012-3277-2
Wolff J, Moritz T, Schlottau K, Hoffmann D, Beer M, Hoffmann B (2020) Development of a safe and highly efficient inactivated vaccine candidate against lumpy skin disease virus. Vaccines 9(1):4. https://doi.org/10.3390/vaccines9010004
World Organisation for Animal Health (WOAH), Asia, (2023). Available online :https://rr-asia.woah.org/wp-content/uploads/2023/03/report-on-lsd-update-meeting-16dec2022.pdf
Yadav P, Kumar A, Nath SS, Devasurmutt Y, Shashidhar G, Joshi M, Puvar A, Sharma S, Raval J, Pandit R, Chavda P (2024) Unravelling the genomic origins of lumpy skin disease virus in recent outbreaks. BMC Genom 25(1):196. https://doi.org/10.1186/s12864-024-10061-3
Yan XM, Chu YF, Wu GH, Zhao ZX, Li J, Zhu HX, Zhang Q (2012) An outbreak of sheep pox associated with goat poxvirus in Gansu province of China. Veterinarymicrobiology 156(3–4):425–428. https://doi.org/10.1016/j.vetmic.2011.11.015
Yeruham I, Perl S, Nyska A, Abraham A, Davidson M, Haymovitch M, Zamir O, Grinstein H (1994) Adverse reactions in cattle to a capripox vaccine. Vet Rec 135(14):330–332. https://doi.org/10.1136/vr.135.14.330
Zeedan GSG, Mahmoud AH, Abdalhamed AM, Abd El-Razik KA, Khafagi MH, Abou Zeina HAA (2019) Detection of lumpy skin disease virus in cattle using real-time polymerase chain reaction and serological diagnostic assays in different governorates in Egypt in 2017. Vet World 12(7):1093–1100. https://doi.org/10.14202/vetworld.2019.1093-1100
Zeynalova S, Asadov K, Guliyev F, Vatani M, Aliyev V (2016) Epizootology and molecular diagnosis of lumpy skin disease among livestock in Azerbaijan. Front Microbiol 7:1022. https://doi.org/10.3389/fmicb.2016.01022
Zheng M, Liu Q, ** N, Guo J, Huang X, Li H, Zhu W, **ong Y (2007) A duplex PCR assay for simultaneous detection and differentiation of Capripoxvirus and Orf virus. Mol Cell Probes 21(4):276–281. https://doi.org/10.1016/j.mcp.2007.01.005
Zhugunissov K, Bulatov Y, Orynbayev M, Kutumbetov L, Abduraimov Y, Shayakhmetov Y, Taranov D, Amanova Z, Mambetaliyev M, Absatova Z, Azanbekova M, Khairullin B, Zakarya K, Tuppurainen E (2020) Goatpox virus (G20-LKV) vaccine strain elicits a protective response in cattle against lumpy skin disease at challenge with lumpy skin disease virulent field strain in a comparative study. Veterinarymicrobiology 245:108695. https://doi.org/10.1016/j.vetmic.2020.108695
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Smaraki, N., Jogi, H.R., Kamothi, D.J. et al. An insight into emergence of lumpy skin disease virus: a threat to Indian cattle. Arch Microbiol 206, 210 (2024). https://doi.org/10.1007/s00203-024-03932-6
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DOI: https://doi.org/10.1007/s00203-024-03932-6