Abstract
2-Amino or 2-hydrazino derivatives of pyridine or pyridinopyrazole were obtained by amination or hydrazination of 2-chloro-3-cyano-4-methoxy-6-methylpyridine. Acid hydrolysis of these derivatives leads to heterocyclization with formation of 4-amino-1H-furo[3,4-c]pyridines or pyrazolo[3,4-b]pyridine. The possibility to synthesize 4-arylamino-1H-furo[3,4-c]-pyridines from 4-chloro-6-methyl-1H-furo[3,4-c]-pyridine has been shown.
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Additional information
V. S. Pustovoit All-Russian Oil-Bearing Crops Research Institute, Krasnodar 350038, Russia. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 61–66, January, 1999.
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Arustamova, I.S., Piven', V.T. Investigations on furopyridines. 10. Synthesis of 4-N-substituted 1H-furo[3,4]pyridin-3-ones. Chem Heterocycl Compd 35, 58–63 (1999). https://doi.org/10.1007/BF02251662
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DOI: https://doi.org/10.1007/BF02251662