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Day-night periodicity in pentobarbital response of mice and the influence of socio-psychological conditions

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Résumé

L'étude de la réaction de la souris à des doses anesthésiques de pentobarbital montre une périodicité nycthémérale. La réaction est forte pendant le jour, faible pendant la nuit. Chez les souris soumises à des conditions qui empêchent l'hypothermie ordinaire de se produire pendant l'anesthésie, l'amplitude de périodicité diminue. La périodicité disparaît le plus souvent lorsqu'on éclaire les souris sans interruption. L'amplitude de la périodicité diminue lorsque les souris sont parquées individuellement plutôt qu'en groupes. Les mécanismes physiologiques répondant à ces observations sont suggérés.

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Authors and Affiliations

  1. University of Oklahoma College of Pharmacy, Norman, Oklahoma, USA

    W. M. Davis

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  1. W. M. Davis
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Additional information

This work was initiated with the aid of a grant from the University of Oklahoma Faculty Research Committee and was later supported by grant B-2250, National Institutes of Health, U.S. Public Health Service.

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Davis, W.M. Day-night periodicity in pentobarbital response of mice and the influence of socio-psychological conditions. Experientia 18, 235–237 (1962). https://doi.org/10.1007/BF02148320

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