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Central precocious puberty: Evaluation by neuroimaging

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Abstract

To evaluate the incidence of abnormal intracranial findings in children with central precocious puberty, 62 children (51 girls, 11 boys) were examined by computerized tomography and/or magnetic resonance imaging (MRI) of the brain. Forty-four had normal examinations; 18 (11 girls, 7 boys) showed intracranial pathologies, including hamartoma of the tuber cinereum (8 cases), parenchymal loss (3 cases), hypothalamicchiasmatic lesions (2 cases), lesions of the corpus callosum (2 cases), suprasellar cyst (1 case), and pineal cyst and mesiotemporal sclerosis (1 case each). Based on the correlation between the clinical and the imaging results of this series, the authors recommend MRI as the imaging method of choice in the investigation of precocious puberty.

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Authors and Affiliations

  1. Department of Pediatric Imaging, The Children's Medical Center of Israel, Beilinson Medical Campus, 49 202, Petah Tiqva, Israel

    L. Kornreich, G. Horev & M. Grunebaum

  2. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

    L. Kornreich, G. Horev & M. Grunebaum

  3. Department of Radiology, Hospital for Sick Children, Toronto, Ontario, Canada

    S. Blaser

  4. Division of Endocrinology, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada

    D. Daneman

  5. Institute of Pediatric and Adolescent Endocrinology, the Children's Medical Center of Israel, Beilinson Medical Campus, Petah Tiqva, Israel

    R. Kauli

  6. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

    R. Kauli

Authors
  1. L. Kornreich
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  2. G. Horev
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  3. S. Blaser
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  4. D. Daneman
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  5. R. Kauli
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  6. M. Grunebaum
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Kornreich, L., Horev, G., Blaser, S. et al. Central precocious puberty: Evaluation by neuroimaging. Pediatr Radiol 25, 7–11 (1995). https://doi.org/10.1007/BF02020830

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  • DOI: https://doi.org/10.1007/BF02020830

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