Summary
An L cell clone develo** cytopathic plaques upon infection with measles virus (Edmonston strain) was obtained. The sensitivity as measured by the newly devised UV-Vero assay was not significantly different between plaque-forming and non-plaque-forming L cell clones. Cytopathogenicity and sensitivity to the virus infection appear to be under different host cell regulations.
References
Bloom BR (1989) Vaccines for the third world. Nature 342: 115–120
Dörig RE, Marcil A, Chopra A, Richardson CD (1993) The human CD46 molecule is a receptor for measles virus (Edmonston strain). Cell 75: 295–305
Dunster LM, Schneider-Schaulies J, Loffler S, Lankes W, Schwartz-Albiez R, Lottspeich F, ter Meulen (1994) Moesin: a cell membrane protein linked with susceptibility to measles virus infection. Virology 198: 265–274
Knight P, Duff R, Rapp F (1972) Latency of human measles virus in hamster cells. J Virol 10: 995–1001
Kohno S, Kohase M, Suganuma M (1968) Growth of measles virus in a mouse derived established cell line L cells. Jpn J Med Sci Biol 21: 301–311
Liszewski MK, Post TW, Atkinson JP (1991) Membrane cofactor protein (MCP or CD46): Newest member of the regulators of complement activation gene cluster. Annu Rev Immunol 9: 431–455
Makino S, Sasaki K, Nazari F, Nakagawa M, Nakamura N, Kasahara S (1970) Cultivation of measles virus in sheep kidney cells. Jpn J Microbiol 14: 501–504
Musser SJ, Slater EA (1962) Measles virus growth in canine renal cell cultures. Am J Dis Child 103: 476–481
Naniche D, Varior-Krishman G, Cervoni F, Wild TF, Rossi B, Rabourdin-Combe C, Gerlier D (1993) Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus. J Virol 67: 6025–6032
Neighbour PA, Rager-Zisman B, Bloom BR (1978) Susceptibility of mice to acute and persistent measles infection. Infect Immun 21: 764–770
Niewiesk S, Brinckmann U, Bankamp B, Sirak S, Liebert UG, ter Meulen V (1993) Susceptibility to measles virus-induced encephalitis in mice correlates with impaired antigen presentation to cytotoxic T lymphocytes. J Virol 67: 75–81
Norrby E, Oxman MN (1990) Measles virus. In: Fields BN, Knipe DM, Chanock RM, Hirsh MS, Melnick JL, Monath TP, Roizman B (eds) Virology, 2nd edn. Raven Press, New York, pp 1013–1044
Rager-Zisman B, Egan JE, Kress Y, Bloom BR (1984) Isolation of cold sensitive mutants of measles virus from persistently infected murine neuroblastoma cells. J Virol 51: 845–855
Rowe WP, Pugh WE, Hartlye JW (1970) Plaque assay techniques for murine leukemia viruses. Virology 42: 1136–1139
Yanagi Y, Hu H-L, Seya T, Yoshikura H (1994) Measles virus infects mouse fibroblast cells lines, but its multiplication is severely restricted in the absence of CD46. Arch Virol 138: 39–53
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Sakae, H., Yoshikura, H. & Yanagi, Y. L cell clone develo** plaques upon infection with measles virus (Edmonston strain). Archives of Virology 139, 427–430 (1994). https://doi.org/10.1007/BF01310803
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DOI: https://doi.org/10.1007/BF01310803