Abstract
Highly purified glicentin , a 69-amino-acid-residue peptide isolated from porcine intestine that contains the full sequence of glucagon and is probably biosynthetically related to glucagon, is a substrate for cyclic-AMP-dependent protein kinase in a cell-free system, Glicentin-related pancreatic peptide (residues 1–30 of glicentin) and glucagon were not phosphorylated under the same reaction conditions. It is postulated that the serine residue at position 34 of glicentin (position 2 of glucagon), t h a t is part of the sequence Lys.Arg. His.Ser., is the probable site of phosphorylation.
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Conlon, J.M., Thim, L., Moody, A.J. et al. Cyclic-AMP-dependent phosphorylation of glicentin. Biosci Rep 4, 489–496 (1984). https://doi.org/10.1007/BF01122224
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DOI: https://doi.org/10.1007/BF01122224