Zusammenfassung
Die Lipase-katalysierte Veresterung von racemischen Heptan-2-ol in organischem Lögsmittel wurde untersucht. Ausgehend von Buttersäure und (R,S)-Heptan-2-ol katalysiert in Heptan suspendierte Schweinepankreas-Lipase bevorzugt die Bildung von (R)-Buttersäure-2-heptylester. Die quantitative Verteilung der Produkte und der stereochemische Verlauf der Reaktion wurde mittels capillargaschromatographischer Methoden untersucht.
Summary
The lipase-catalysed esterification of racemic heptan-2-ol in organic solvent has been investigated. Porcine pancreas lipase, suspended in heptane, preferentially catalyses the synthesis of (R)-2heptyl butyrate starting from (R,S)-heptan-2-ol and butyric acid. The distribution of the reaction products and the stereochemical course of the esterification have been investigated by means of capillary gas chromatographic methods.
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Engel, KH., Bohnen, M. & Tressl, R. Kinetic resolution of heptan-2-ol-enantiomers by lipase-catalysed esteriîication in organic solvent. Z Lebensm Unters Forch 188, 144–147 (1989). https://doi.org/10.1007/BF01042739
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DOI: https://doi.org/10.1007/BF01042739