Summary
Fed-batch culture ofRhodotorula glutinis, an oleaginous yeast, was carried out to obtain high biomass concentration. With air, final concentration of biomass was 100–110 g/L, whereas with oxygen-enriched air, 185 g/L was obtained. Obligate aerobic metabolism ofR. glutinis under oxygen limitation and low oxygen requirement under lipidaccumulating condition were found to be advantageous for the high density culture of this microbe.
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Pan, J.G., Kwak, M.Y. & Rhee, J.S. High density cell culture ofRhodotorula glutinis using oxygen-enriched air. Biotechnol Lett 8, 715–718 (1986). https://doi.org/10.1007/BF01032568
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DOI: https://doi.org/10.1007/BF01032568