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A contribution to the formation mechanism of calcium oxalate urinary calculi

I. Stabilising urinary constitutents in the formation of weddellite

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Summary

25 to 30% of calcium oxalate urinary calculi consist of the metastable Weddellite crystal phase. By fractionation of urine it was found that mineral substances are stabilising factors. The stability was checked in dry condition at room temperature, at 38°C and at 110°C. These results could be confirmed by precipitation from synthetic solutions. Mg, Zn, Ni, Co, Mn and Cu individually, and above all in combination, promote the formation of Weddellite. The formation of mixed crystal phases must be considered one of the main factors for the stabilisation of Weddelite in the urinary calculus.

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References

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Hesse, A., Berg, W., Schneider, H.J. et al. A contribution to the formation mechanism of calcium oxalate urinary calculi. Urol. Res. 4, 125–128 (1976). https://doi.org/10.1007/BF00257168

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  • DOI: https://doi.org/10.1007/BF00257168

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