Log in

Surveillance of antibiotic resistance in South East Asia

  • Published:
European Journal of Epidemiology Aims and scope Submit manuscript

Abstract

Antibiotic resistance in Gram-negative bacteria, particularly Salmonella and Shigella, requires surveillance worldwide. This study describes results of surveys in Hong Kong, Bangkok and Kuala Lumpur. All strains were isolated in hospitals which have large community catchment areas in addition to specialised hospital units. The prevalence of resistant strains was high in all areas. Gram-negative bacteria such as Enterobacter associated with hospital infections were resistant to penicillins and cephalosporins, with gentamicin resistance ranging from about 20% in Kuala Lumpur and Hong Kong, to 35% in Bangkok. Ninety-seven percent of Shigella isolated in Thailand were resistant to ampicillin. About 10% of Salmonella were resistant to chloramphenicol in all three centres.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Germany)

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Brumfitt W., Hamilton-Miller J.M.T. and Wood A. (1983): Evidence for a slowing in trimethoprim resistance in 1981 — a comparison with early years. - J. Antimicrob. Chemother. 11: 503–509.

    Google Scholar 

  2. Escheverria P., Verhaert L., Olyangco C.V., KomaliriniS., Ho M.T., Orskov F and Orskov I. (1978): Antimicrobial resistance and enterotoxin production among isolates of Escherichia coli in the Far East. -Lancet 2: 589–592.

    Google Scholar 

  3. Goldstein F.W., Chumpitaz J.C., Guevara J.M., Papadopoulou B., Acar J.F. and Vieu J.F. (1986): Plasmid-mediated resistance to multiple resistance in Salmonella typhy. J. Infect. Dis. 153: 261–266.

    Google Scholar 

  4. Goldstein F.W., Papadopoulou B. and Acar J.F. (1983): Epidemiologie et mecanismes de la resistance aux sulfamides et au trimethoprime. - Societe de Pathologie Infectieuse de Langue Francaise 49–69.

  5. Murray B.E., Alvarado T., Kimpo K.H., Vorachit M., Jayanetra P., Levine M.M., Prenzel I., FlingM., Elwell L., McCracken G.H., Madrigal G., Odio C. and Trabulsi L.R. (1985): Increasing resistance to trimethoprim-sulphamethoxazole among isolates of Escherichia coli in develo** countries. - J. Infect. Dis. 152: 1107–1113.

    Google Scholar 

  6. National Committee for Clinical Laboratory Standards Subcommittee on Disk Diffusion Susceptibility Testing (1984): Performance Standards for antimicrobial disk susceptibility tests. Approved standard M2-A3. 3rd edition. - National Committee for Clinical Laboratory Standards, Villanova, Pa.

    Google Scholar 

  7. Roy C., Segura C., Tirado M., Reig R., HermidaM., Teruel D. and Foz A. (1985): Frequency of plasmid-determined beta-lactamases in 680 consecutively isolated strains of Enterobacteriacea. - Eur. J. Clin. Microbiol. 4: 146–147.

    Google Scholar 

  8. Shahid N.S., Rahaman M.M., Haider K., Banu H. and Rahman N. (1985): Changing pattern of resistant Shiga bacillus (Shigella dysenteriae type 1) and Shigella flexneri in Bangladesh. - J. Infect. Dis. 152: 1114–1119.

    Google Scholar 

  9. WHO Surveillance for the prevention and control of health hazards due to antibiotic-resistant enterobacteria (1978): Report of a WHO meeting. WHO Tecnical Report Series, no. 624.

  10. Whitaker S., Hajipieris P. and Williams J.D. (1983): Distribution and type of beta-lactamase among, 1,000 Gram-negative rod bacteria. — Proceedings of 13th International Congress of Chemotherapy, Vienna PS2.5/1-3.

  11. Williams R.J., Lindridge M., Said A.A.Livermore D.M. and Williams J.D. (1984): National survey of antibiotic resistance in Pseudomonas aeruginosa. J. Antimicrob. Chemother. 14: 9–16.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Williams, J.D., Moosdeen, F., Teoh-Chan, C.H. et al. Surveillance of antibiotic resistance in South East Asia. Eur J Epidemiol 5, 207–213 (1989). https://doi.org/10.1007/BF00156832

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00156832

Key words

Navigation