Sherulitic and an aggregate of bow shaped crystals of monosodium urate monohydrate which had a close resemblance to that of those crystals found in gouty synovial fluids and articular cartilage have been grown using tetramethoxysilane and silica gel.
Thermogravimetric analysis (TGA), and infrared (IR) and X-ray diffraction were used to analyse the grown samples. Crystals were obtained for a wide range of pH (3–10), without using any biological component at room temperature and were found to be monohydrate form of monosodium urate.
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P. A. DIEPPE and P. CALVERT, “Crystals and joint disease”, (Chapman & Hall, London, 1983).
J. E. Z. CANER and J. L. DECKER, Amer. J. Med. 36 (1964) 571.
J. F. FIECHTNER and P. A. SIMKIN, JAMA 245 (1981) 1533.
A. HAYES, I. G. TURNER, K. A. POWELL and P. A. DIEPPE, J. Mater. Sci. Mater. Med. 3 (1992) 75.
N. W. McGILL and P. A. DIEPPE, Brit. J. Rheum. 30 (1991) 107
N. S. MANDEL and G. S. MANDEL, J. Amer. Chem. Soc. 98 (1976) 2319.
S. N. ALKURA, V. K. VAIDYAN, M. KANAKAVEL and P. RAMASAMY, J. Cryst. Growth 132 (1993) 617.
S. N. KALKURA and S. DEVANARAYANAN, J. Cryst. Growth 110 (1991) 265.
S. DEVANARAYANAN and S. N. KALKURA, J. Mater. Sci. Lett. 10 (1991) 497.
L. J. BELLAMY, “Infrared spectra of complex molecules” (Chapman & Hall, London, 1975).
V. R. KODATI, A. T. TU and J. L. TURUMIN, Appl. Spectrosc. 44 (1990) 1134.
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Kalkura, S.N., Girija, E.K., Kanakavel, M. et al. In-vitro crystallization of spherulites of monosodium urate monohydrate. J Mater Sci: Mater Med 6, 577–580 (1995). https://doi.org/10.1007/BF00121281
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DOI: https://doi.org/10.1007/BF00121281